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Catalog	name	Description	price
R-R-3783	Detomidine hydrochloride CAS No.90038-01-0	Detomidine hydrochloride/CAS No.90038-01-0, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine hydrochloride produces dose-dependent analgesic effects.	price>
R-C-2084	Belvarafenib (HM95573) CAS:1446113-23-0	Belvarafenib(GDC5573,HM95573,RG6185)is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM,7nM and 2nM for BRAF WT, BRAF(V600E)and CRAF kinases,respectively.	price>
R-R-3784	Hydrocortisone 17-butyrate CAS No.13609-67-1	Hydrocortisone 17-butyrate/CAS No.13609-67-1 is an adrenocortical hormone active molecule.	price>
R-C-2085	Q-VD-OPh hydrate CAS:1135695-98-5	Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties,inhibits caspase 7 with an IC50 of 48nM and 25-400nM for other caspases including caspase 1,3,8,9,10,and 12.Q-VD-OPh can inhibits HIV infection.Q-VD-OPh is able to cross the blood-brain barrier.	price>
R-R-3785	Ro 363 hydrochloride CAS No.250580-70-2	Ro 363 hydrochloride/CAS No.250580-70-2, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility.	price>
R-C-2086	GSK2983559 FREE ACID CAS:1579965-12-0	GSK2983559 free acid(compound 3)is a potent,specific and oral active receptor interacting protein 2(RIP2)kinase inhibitor.GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.	price>
R-R-3786	Lofexidine CAS No.31036-80-3	Lofexidine/CAS No.31036-80-3 is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.	price>
R-C-2087	Elexacaftor (VX-445) CAS:2216712-66-0	Elexacaftor(VX-445,Compound 1)is a modulator of cystic fibrosis transmembrane conductance regulator(CFTR).Elexacaftor(VX-445,Compound 1)facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.	price>
R-R-3787	Tulobuterol CAS No.41570-61-0	Tulobuterol (C-78 free base)/CAS No.41570-61-0 is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.	price>
R-C-2088	azd4635 CAS:1321514-06-0	AZD4635(HTL1071)is a potent,selective and orally active adenosine A2A receptor(A2AR)antagonist.AZD4635 binds to human A2AR with a Ki of 1.7nM and shows>30-fold selectivity over other adenosine receptors.	price>
R-R-3788	Metipranolol CAS No.22664-55-7	Metipranolol/CAS No.22664-55-7 is a nonselective and orally active β-adrenergic receptor antagonist. Metipranolol can be used for hypertension and glaucoma research.	price>
R-R-3789	Denopamine CAS No.71771-90-9	Denopamine ((R)-(-)-Denopamine)/CAS No.71771-90-9 is an orally active, selective β1-adrenergic agonist. Denopamine prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart. Cardiovascular effects.	price>
R-C-2090	G1T38 CAS：1628256-23-4	Lerociclib(G1T38)is a potent and selective inhibitor of CDK4/6,with IC50s of 1 nM,2nM for CDK4/CyclinD1 and CDK6/CyclinD3,respectively.	price>
R-R-3790	DL-Norepinephrine-d6 hydrochloride CAS No.1219803-04-9	DL-Norepinephrine-d6 (hydrochloride)/CAS No.1219803-04-9 is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial oxygen tension.	price>
R-C-2091	Firsocostat (GS-0976) CAS：1434635-54-7	Firsocostat(ND-630;GS-0976;NDI-010976)is an acetyl-CoA carboxylase(ACC) inhibitor;inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1nM, respectively.	price>
R-R-3791	Atenolol-d7 CAS No.1202864-50-3	Atenolol-d7/CAS No.1202864-50-3 is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris.	price>
R-C-2092	Resatorvid (TAK-242) CAS：243984-11-4	Resatorvid(TAK-242,CLI-095)is a small-molecule-specific inhibitor of Toll-like receptor(TLR)4 signaling,blocking LPS-induced production of NO,TNF-α and IL-6 in macrophages with IC50 of 1.8nM,1.9nM and 1.3nM,respectively.Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.	price>
R-R-3792	Bretylium tosylate CAS No.61-75-6	Bretylium (tosylate)/CAS No.61-75-6 is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters.	price>
R-R-3793	Etilefrine hydrochloride CAS No.943-17-9	Etilefrine hydrochloride/CAS No.943-17-9 is an orally active α adrenergic agonist. Etilefrine hydrochloride is also an AMPK activator. Etilefrine hydrochloride can be used for the research of postural hypotension.	price>
R-C-2094	PF06869206 CAS：2227425-05-8	PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a(SLC34A1)with an IC50 of 380nM.	price>

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