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R-C-2185 Alectinib (CH5424802) CAS: 1256580-46-7 Alectinib(CH5424802)is a potent,selective,and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4nM(in an ATP-competitive manner),and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1nM and 3.5 nM,respectively.Alectinib demonstrates effective central nervous system(CNS) penetration. price>
R-R-3885 PP/Al2O3 composite aerogel PP/Al2O3 composite aerogel;Polypropylene/alumina composite aerogel;PP/alumina composite aerogel;Polypropylene/Al2O3 composite aerogel from ruixi.The polypropylene/alumina composite aerogel is a sophisticated material achieved by infusing nanoporous, lightweight polypropylene with alumina nanoparticles.The polypropylene/alumina composite aerogel exhibits a combination of properties including thermal insulation, mechanical strength, chemical resistance, biocompatibility, fire resistance, electrical insulation, and catalytic potential. These properties make it applicable in industries such as construction, healthcare, chemical processing, environmental remediation, and electrical engineering. price>
R-C-2186 AP26113-analog (ALK-IN-1) AP26113 is an orally-available,potent,and selective inhibitor of ALK with a potency of 0.62nM against wild-type and activity against a wide range of mutants,including the crizotinib-resistant L1196M line.In a panel of EML4-ALK or NPM-ALK-positive cell lines,AP26113 has IC50 values of 4-31 nM.AP26113 is effective against sensitive and resistant H3122 cells,reducing cell growth, suppressing ALK phosphorylation,and inducing apoptosis. price>
R-R-3886 PP/CNT composite aerogel PP/CNT composite aerogel;Polypropylene/carbon nanotube composite aerogel;PP/carbon nanotube composite aerogel;Polypropylene/CNT composite aerogel from ruixi.The polypropylene/carbon nanotube composite aerogel is an innovative material created through the integration of carbon nanotubes into a nanoporous, lightweight polypropylene matrix.The polypropylene/carbon nanotube composite aerogel exhibits a combination of properties including lightweight high strength, electrical and thermal conductivity, mechanical flexibility, chemical resistance, and potential for energy storage. These properties make it applicable in industries such as aerospace, automotive, electronics, energy storage, environmental monitoring, and healthcare. price>
R-C-2187 Ceritinib dihydrochloride CAS:1380575-43-8 Ceritinib dihydrochloride(LDK378 dihydrochloride)is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM.Ceritinib dihydrochloride(LDK378 dihydrochloride)also inhibits IGF-1R,InsR,and STK22D with IC50 values of 8,7,and 23nM,respectively.Ceritinib dihydrochloride(LDK378 dihydrochloride)shows great antitumor potency. price>
R-R-3887 PP/ATP composite aerogel PP/ATP composite aerogel;Polypropylene/attapulgite composite aerogel;PP/attapulgite composite aerogel;Polypropylene/ATP composite aerogel from ruixi.The polypropylene/attapulgite composite aerogel represents an advanced material achieved by integrating nanoporous, lightweight polypropylene with attapulgite nanoparticles. The polypropylene/attapulgite composite aerogel presents a combination of properties including thermal insulation, mechanical strength, absorbency, fire resistance, rheological properties, and potential for environmental and biomedical applications. These properties make it applicable in industries such as construction, environmental remediation, healthcare, and materials engineering. price>
R-C-2188 Dasatinib (BMS-354825) CAS:302962-49-8 Dasatinib(BMS-354825)is an oral multi-BCR/ABL and Src family tyrosine kinase inhibitor.The main targets of dasatinib,are BCR/ABL,Src,c-Kit,ephrin receptors, and several other tyrosine kinases,but not erbB kinases such as EGFR or Her2. price>
R-R-3888 PP/PDA composite aerogel PP/PDA composite aerogel;Polypropylene/polydopamine composite aerogel;PP/polydopamine composite aerogel;Polypropylene/PDA composite aerogel from ruixi.The polypropylene/polydopamine composite aerogel is a cutting-edge material that results from the integration of nanoporous, lightweight polypropylene with polydopamine nanoparticles. The polypropylene/polydopamine composite aerogel offers a unique combination of properties including enhanced mechanical strength, surface modification capabilities, bioadhesive and biocompatible properties, chemical resistance, electrochemical properties, sorptive capability, thermal stability, and potential for functionalization and nanoparticle encapsulation. These properties make it applicable in industries such as biomedical engineering, environmental remediation, energy storage, catalysis, and materials science. price>
R-C-2189 XL228 CAS:898280-07-4 XL228 is a protein kinase inhibitor targeting IGF1R,the AURORA kinases,FGFR1-3, ABL and SRC family kinases.XL228 is an Aurora A inhibitor(IC50,f3 nmol/L)that has shown potent biochemical activity against ABL1(Ki,5 nmol/L)as well as the BCR-ABL1 T315I(Ki,1.4 nmol/L)kinases. price>
R-R-3889 PP/Fe3O4 composite aerogel PP/Fe3O4 composite aerogel;Polypropylene/Fe3O4 composite aerogel from ruixi.The polypropylene/Fe3O4 composite aerogel is an advanced material resulting from the combination of nanoporous, lightweight polypropylene with iron(II,III) oxide (Fe3O4) nanoparticles. The polypropylene/Fe3O4 composite aerogel offers a unique combination of magnetic properties, mechanical strength, catalytic activity, biomedical imaging potential, adsorption capabilities, thermal conductivity, lightweight structure, and reusability. These properties make it applicable in industries such as biotechnology, environmental science, catalysis, nanotechnology, materials engineering, and healthcare. price>
R-C-2190 Nilotinib (AMN-107) CAS: 641571-10-0 Nilotinib(AMN107)is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.Nilotinib is a selective Bcr-Abl kinase inhibitor that is 10-30 fold more potent than imatinib in inhibiting Bcr-Abl tyrosine kinase activity and proliferation of Bcr-Abl expressing cells. price>
R-R-3890 PP/BaTiO3 composite aerogel PP/BaTiO3 composite aerogel;Polypropylene/barium titanate composite aerogel;PP/barium titanate composite aerogel;Polypropylene/BaTiO3 composite aerogel from ruixi. The polypropylene/barium titanate composite aerogel is an innovative material resulting from the combination of nanoporous, lightweight polypropylene with barium titanate nanoparticles. The polypropylene/barium titanate composite aerogel presents exceptional dielectric properties, tunable electrical behavior, mechanical flexibility, energy storage potential, sensing capabilities, lightweight structure, and potential thermal stability. These properties make it applicable in industries such as electronics, telecommunications, energy storage, sensors, and advanced materials for various technological applications. price>
R-C-2191  Danusertib (PHA-739358) CAS:827318-97-8 Danusertib(PHA-739358)is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases,which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed.This agent may preferentially bind to and inhibit Aurora B kinase.Aurora kinases,a family of serine-threonine kinases,are important regulators of cellular proliferation and division. price>
R-R-3891 PP/TiO2 composite aerogel PP/TiO2 composite aerogel;Polypropylene/titanium dioxide composite aerogel;PP/titanium dioxide composite aerogel;Polypropylene/TiO2 composite aerogel from ruixi.The polypropylene/titanium dioxide composite aerogel is a cutting-edge material formed by combining nanoporous, lightweight polypropylene with titanium dioxide nanoparticles. The polypropylene/titanium dioxide composite aerogel offers outstanding photocatalytic activity, UV protection, lightweight structure, mechanical flexibility, antimicrobial properties, potential use in photovoltaic applications, and environmental remediation capabilities. These properties make it applicable in industries such as environmental engineering, materials science, construction, healthcare, and renewable energy, among others. price>
R-C-2192 Degrasyn (WP1130) CAS:856243-80-6 WP1130(Degrasyn)is a novel selective small molecular deubiquitinase inhibitor and a Bcr/Abl destruction pathway activator that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression in chronic myelogenous leukemia(CML)cells. price>
R-R-3892 Levobetaxolol hydrochloride CAS No.116209-55-3 Levobetaxolol hydrochloride/CAS No.116209-55-3 is a beta-adrenergic receptor inhibitor (beta blocker) that can lower the pressure in the eye. price>
R-C-2193 KW-2449 CAS:1000669-72-6 KW-2449 is a multi-targeted kinase inhibitor of FLT3,ABL,ABLT315I and Aurora kinase with IC50s of 6.6,14,4 and 48nM.respectively. price>
R-R-3893 Tizanidine CAS No.51322-75-9 Tizanidine/CAS No.51322-75-9 is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. price>
R-C-2194 PP121 CAS:1092788-83-4 PP121 is a dual inhibitor of receptor tyrosine kinases(RTKs)(IC50<0.02μM for Abl,Src,VEGFR-2 and PDGFR)and PI 3-K family kinases(IC50<0.06μM for p110α,DNA-PK and mTOR). price>
R-R-3894 Harmane-d Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). price>