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Catalog	name	Description	price
R-R-3933	Bisoprolol-d5 CAS No.1189881-87-5	Bisoprolol-d5/CAS No.1189881-87-5 is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research.	price>
R-C-2234	Triciribine (NSC 154020) CAS:35943-35-2	Triciribine(VQD-002)is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity.Triciribine inhibits the phosphorylation,activation, and signalling of Akt-1,-2,and-3,which may result in the inhibition of Akt-expressing tumor cell proliferation.Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery,including Bcl-xL/Bcl-2-associated death promoter(BAD)and caspase 9.	price>
R-R-3934	Atomoxetine-d3 hydrochloride CAS No.1217776-38-9	Atomoxetine-d3 hydrochloride/CAS No.1217776-38-9 is the deuterium labeled Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively).	price>
R-C-2235	CCT128930 CAS： 885499-61-6	CCT128930 is a potent,ATP-competitive and selective inhibitor of Akt2 with IC50 of 6nM in a cell-free assay,28-fold greater selectivity for Akt2 than the closely related PKA kinase.CCT128930 induces cell cycle arrest,DNA damage,and autophagy independent of Akt inhibition.High dose of CCT128930 triggers cell apoptosis in HepG2 cells.	price>
R-R-3935	Doxazosin-d8 hydrochloride CAS No.1219803-95-8	Doxazosin-d8 (hydrochloride)/CAS No.1219803-95-8 is the deuterium labeled Doxazosin hydrochloride.	price>
R-C-2236	Miltefosine CAS：58066-85-6	Miltefosine(Hexadecylphosphocholine)inhibits PI3K/Akt activity with ED50 of 17.2μM and 8.1μM in carcinoma cell lines A431 and HeLa,first oral drug for Visceral leishmaniasis,effective against both promastigotes and amastigotes.	price>
R-R-3936	Celiprolol-d9 hydrochloride CAS No.1215535-20-8	Celiprolol-d9 (hydrochloride)/CAS No.1215535-20-8 is the deuterium labeled Celiprolol hydrochloride.	price>
R-C-2237	Honokiol (NSC 293100) CAS：35354-74-6	Honokiol is a lignan present in the cones,bark,and leaves of Magnolia grandiflora that has shown pro-apoptotic effects in melanoma,sarcoma,myeloma, leukemia,bladder,lung,prostate,oral squamous cell carcinoma and colon cancer cell lines.	price>
R-R-3937	Salbutamol-d9 CAS No.1173021-73-2	Salbutamol-d9/CAS No.1173021-73-2 is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).	price>
R-C-2238	TIC10 isomer CAS：41276-02-2	TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a,possesses superior drug properties:delivery across the blood-brain barrier,superior stability and improved pharmacokinetics.	price>
R-R-3938	Clonidine-d4 hydrochloride CAS No.67151-02-4	Clonidine-d4 (hydrochloride)/CAS No.67151-02-4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an alpha 2-adrenergic agonist.	price>
R-R-3939	Terbutaline-d9 CAS No.1189658-09-0	Terbutaline-d9/CAS No.1189658-09-0 is the deuterium labeled Terbutaline.	price>
R-C-2240	Borussertib CAS：1800070-77-2	Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt,with an IC50 of 0.8nM and a Ki of 2.2nM for Aktwt.	price>
R-R-3940	Carteolol-d9 hydrochloride CAS No.1346602-13-8	Carteolol-d9 (hydrochloride)/CAS No.1346602-13-8 is the deuterium labeled Carteolol hydrochloride. Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma.	price>
R-C-2241	Lanatoside C CAS：17575-22-3	Lanatoside C is a cardiac glycoside,can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19μM for dengue virus infection in HuH-7 cells.	price>
R-R-3941	Indacaterol-d3 CAS No.2699828-16-3	Indacaterol-d3/CAS No.2699828-16-3 is deuterium labeled Indacaterol.	price>
R-C-2242	Uprosertib (GSK2141795) CAS：1047634-65-0	Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt,which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.	price>
R-R-3942	Naftopidil-d5 CAS No.2747918-58-5	Naftopidil-d5/CAS No.2747918-58-5 is deuterium labeled Naftopidil. Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia.	price>
R-C-2243	Notoginsenoside R1 CAS：80418-24-2	Notoginsenoside R1(Sanchinoside R1),a saponin,is isolated from P.notoginseng. Notoginsenoside R1 exhibits anti-oxidation,anti-inflammatory,anti-angiogenic,and anti-apoptosis activities.Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion(I/R)injury.Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells.	price>
R-R-3943	Prazobind CAS No.107021-36-3	Prazobind (SZL 49)/CAS No.107021-36-3, a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50=1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes.	price>

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