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R-C-2271 TK216 CAS:1903783-48-1 TK216 is an orally active and potent E26 transformation specific (ETS)inhibitor.TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions.TK216 blocks the binding between EWS-FLI1 and RNA helicase A.TK216 has anticancer activity. price>
R-R-3971 RS100329 hydrochloride CAS No.1215654-26-4 RS100329 hydrochloride/CAS No.1215654-26-4 is a potent and selective α1A-adrenoceptor antagonist with pKi values of 9.6, 7.9 and 7.5 for α1A, α1D, and α1B, respectively. RS100329 hydrochloride inhibits reflex urethral contractions. RS100329 hydrochloride can be used in research of benign prostatic hyperplasia. price>
R-C-2272 GC7 Sulfate CAS:150417-90-6 GC7(N1-guanyl-1,7-diaminoheptane)Sulfate is an inhibitor of deoxyhypusine synthase(DHPS).GC7 inhibits Neuroblastoma(NB)cell proliferation in a dose-dependent manner,through induction of the cell cycle inhibitor p21 and reduction of total and phosphorylated Rb proteins. price>
R-R-3972 Agroclavine CAS No.548-42-5 Agroclavine/CAS No.548-42-5 is a natural, clavine type of ergot alkaloid. Agroclavine is a D1 dopamine receptor and α1-adrenoceptor agonist. Agroclavine also has anticancer and antimicrobial activities. price>
R-C-2273 Capecitabine(RO 09-1978) CAS:154361-50-9 Capecitabine(RO 09-1978)is a tumor-selective fluoropyrimidine carbamate,which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. Capecitabine treatment of HCT-15 cells causes condensation of DNA and induces apoptosis. price>
R-R-3973 Brombuterol hydrochloride CAS No.21912-49-2 Brombuterol hydrochloride (Bromobuterol hydrochloride)/CAS No.21912-49-2 is a β-adrenergic receptor agonist. price>
R-C-2274 Cidofovir CAS: 113852-37-2 Cidofovir is an anti-CMV drug which can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. price>
R-R-3974 (Rac)-Nebivolol CAS No.99200-09-6 (Rac)-Nebivolol ((Rac)-R 065824)/CAS No.99200-09-6 is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity. price>
R-C-2275 Cytarabine (U-19920A) CAS:147-94-4 Cytarabine(U-19920A,Cytarabin,Ara-C,Arabinofuranosyl Cytidine,Cytosine β-D-arabinofuranoside,Cytosine arabinoside,NSC 63878,NSC 287459)is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.Cytarabine induces autophagy and apoptosis. price>
R-R-3975 Terbutaline sulfate (Standard) CAS No.23031-32-5 Terbutaline (sulfate) (Standard)/CAS No.23031-32-5 is the analytical standard of Terbutaline (sulfate). This product is intended for research and analytical applications. Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol. Terbutaline sulfate can be used in asthma symptom research. price>
R-C-2276 Gemcitabine (LY-188011) CAS:95058-81-4 Gemcitabine(LY 188011)is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent.Gemcitabine inhibits DNA synthesis and repair,resulting in autophagyand apoptosis. price>
R-R-3976 Isoxsuprine-d6 hydrochloride CAS No.2706004-35-3 Isoxsuprine-d6 (hydrochloride)/CAS No.2706004-35-3 is the deuterium labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist. price>
R-C-2277 Nelarabine CAS:121032-29-9 Nelarabine(Arranon,506U78)is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15μM in tumor cells. price>
R-R-3977 Azepexole dihydrochloride CAS No.36067-72-8 Azepexole (B-HT 933) dihydrochloride/CAS No.36067-72-8 is a potent and selective alpha 2-adrenoceptor agonist with pKis of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions (IC50= 78.72 nM). price>
R-C-2278 Cladribine (RWJ 26251) CAS:4291-63-8 Cladribine(RWJ 26251,Leustatin,2-CdA,2-chlorodeoxyadenosine,2-Chloro-2-deoxyadenosine,CldAdo,Jk 6251,NSC 105014)is an adenosine deaminase inhibitor for U266,RPMI8226,and MM1.S cells with IC50 of approximately 2.43μM,0.75μM,and 0.18μM,respectively. price>
R-R-3978 Betaxolol-d7 hydrochloride CAS No.1219802-92-2 Betaxolol-d7 (hydrochloride)/CAS No.1219802-92-2 is the deuterium labeled Betaxolol hydrochloride. Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. price>
R-C-2279 Raltitrexed CAS:112887-68-0 Raltitrexed(Tomudex)is an inhibitor of thymidylate synthase and also is one of the strongest antimetabolites in use. price>
R-R-3979 Cimbuterol CAS No.54239-39-3 Cimbuterol/CAS No.54239-39-3 is a β-adrenergic receptor agonist. price>
R-C-2280 Clofarabine CAS:123318-82-1 Clofarabine is a second generation purine nucleoside analog with antineoplastic activity.Clofarabine is phosphorylated intracellularly to the cytotoxic active 5-triphosphate metabolite,which inhibits the enzymatic activities of ribonucleotide reductase and DNA polymerase,resulting in inhibition of DNA repair and synthesis of DNA and RNA.This nucleoside analog also disrupts mitochondrial function and membrane integrity,resulting in the release of pre-apoptotic factors,including cytochrome C and apoptotic-inducing factor,which activate apoptosis. price>
R-R-3980 Tizanidine-d4 hydrochloride CAS No.1188263-51-5 Tizanidine-d4 (hydrochloride)/CAS No.1188263-51-5 is deuterium labeled Tizanidine (hydrochloride). price>