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R-C-2313 Cinepazide maleate CAS:26328-04-1 Cinepazide Maleate(MD-67350)is a piperazine derivative and acts as a weak calcium channel blocker.Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases,including ischemic stroke,brain infarct et.al. price>
R-R-4013 Potassium tetrachloroplatinate(II) CAS :10025-99-7 Potassium tetrachloroplatinate(II)/CAS :10025-99-7 is a metal chelate of potassium and platinum. It can be used as a catalyst for organic syntheses, such as hydrogenation reactions. Potassium tetrachloroplatinate(II) has a high affinity for the amide ligands in substrates, which allows it to be used for hydrogenation reactions. The reaction mechanism of this compound has been investigated by x-ray crystal structures and in vitro experiments. The reaction mechanism primarily involves the formation of an organometallic intermediate that subsequently reacts with the substrate via an addition-elimination process. This compound also emits light when heated and produces a dark red color due to its ability to absorb visible light. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2314 Nicardipine CAS:55985-32-5 Nicardipine(YC-93 free base)is a calcium channel blocker with an IC50 of 1μM for blocking cardiac calcium channels.Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure. price>
R-R-4014 (±)-BINAP CAS :98327-87-8 The compound (±)-BINAP/CAS :98327-87-8 is a chelate ligand that binds to metal ions. It has been shown to inhibit the reaction between amines and trifluoroacetic acid, as well as between amines and tiglic acid. The reaction mechanism of this compound is not fully understood. However, it has been shown to be a potent antagonist in reactions involving nitrogen atoms with the ligand binap. (±)-BINAP is a white solid that can act as a catalyst for asymmetric synthesis. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2315 YM-58483 (BTP2) CAS:223499-30-7 YM-58483(BTP2)is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.YM-584832 is a blocker of store-operated Ca2+entry(SOCE). price>
R-R-4015 Tetrakis(triphenylphosphine) palladium CAS:14221-01-3 Tetrakis(triphenylphosphine) palladium/CAS:14221-01-3 Catalyst for coupling reactions (e.g. Suzuki, Sonogashira, Negishi and Stille) We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time.Tetrakis(triphenylphosphine) palladium/CAS:14221-01-3 Catalyst for coupling reactions (e.g. Suzuki, Sonogashira, Negishi and Stille) We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2316 Efonidipine CAS:111011-63-3 Efonidipine(NZ-105)is an L-and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart.It also suppresses aldosterone secretion from the adrenal. price>
R-R-4016 1,2-Bis(4-hexylphenyl)ethane-1,2-dione CAS :869081-44-7 1,2-Bis(4-hexylphenyl)ethane-1,2-dione/CAS :869081-44-7 is an active pharmaceutical ingredient.It finds applic ation in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2317 Panaxadiol CAS:19666-76-3 Panaxadiol(20(R)-Panaxadiol)is a triterpene sapogenin originally found in species of Panax(ginseng)and exhibits anticancer,cardioprotective,anti-arrhythmic,and antioxidative activities.It inhibits Ca2+ channels,decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential. price>
R-R-4017 TRV055 hydrochloride TRV055 hydrochloride, a G-protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV055 hydrochloride is efficacious in stimulating cellular Gq-mediated signaling. price>
R-C-2318 CM 4620 CAS:1713240-67-5 CM 4620 is an inhibitor of calcium-release activated calcium-channel(CRAC channel).CM4620 inhibits Orai1/STIM1-mediated Ca2+ currents and Orai2/STIM1-mediated currents with IC50 of near 120 nM and 900 nM. price>
R-R-4018 TRV056 CAS No.812644-79-4 TRV056/CAS No.812644-79-4 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists. price>
R-C-2319 Columbianadin CAS:5058-13-9 Columbianadin(Zosimin,2-Butenoic acid),a natural coumarin from Angelica decursiva,is known to have various biological activities including calcium-channel blocking activity,cytotoxic activity against various cancer cell lines,analgesic activities,intestinal absorption and transportation,anti-inflammatory and anti-cancer effects. price>
R-R-4019 TRV055 CAS No.25849-90-5 TRV055/CAS No.25849-90-5, a G-protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV055 is efficacious in stimulating cellular Gq-mediated signaling. price>
R-C-2320 Tetrandrine (NSC-77037) CAS:518-34-3 Tetrandrine(NSC-77037;d-Tetrandrine)is a bis-benzyl-isoquinoline alkaloid,which inhibits voltage-gated Ca2+ current(ICa)and Ca2+-activated K+ current. price>
R-R-4020 Norleual TFA Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities. price>
R-C-2321 Praeruptorin A CAS:73069-27-9 Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum(also known as Bai-Hua Qian Hu).Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation. price>
R-R-4021 GSK1820795A CAS No.2650253-86-2 GSK1820795A/CAS No.2650253-86-2, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38). price>
R-C-2322 Ginsenoside Rd CAS: 52705-93-8 Ginsenoside Rd(Panaxoside Rd,Sanchinoside Rd),a minor ginseng saponin,has several pharmacological activities such as immunosuppressive activity,anti-inflammatory activity,immunological adjuvant,anti-cancer activity and wound-healing activity.Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells.Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA.Ginsenoside Rd also inhibits Ca2+ influx. price>
R-R-4022 Azilsartan-d5 CAS No.1346599-45-8 Azilsartan-d5/CAS No.1346599-45-8 is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist. price>