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Catalog	name	Description	price
R-R-4100	GAT211 CAS No.102704-40-5	GAT211/CAS No.102704-40-5 is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM). GAT211 activates cAMP and β-arrestin2 with EC50 values of 260 nM and 650 nM, respectively. GAT211 inhibits GAT211 can be used for neuropathic and/or inflammatory pain research.	price>
R-C-2401	Fargesin CAS:31008-19-2	Fargesin is a lignan from Magnolia fargesii,an oriental medicine used in the treatment of nasal congestion and sinusitis.Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB.	price>
R-R-4101	CB2R PAM CAS No.2244579-87-9	CB2R PAM/CAS No.2244579-87-9 is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator. CB2R PAM displays antinociceptive activity in vivo in an experimental mouse model of neuropathic pain.	price>
R-C-2402	Dapiprazole Hydrochloride CAS:72822-13-0	Dapiprazole Hydrochloride(Glamidolo Hydrochloride,Reversil Hydrochloride)is the hydrochloride salt form of dapiprazole,an alpha-adrenergic blocker used to reverse mydriasis after eye examination.	price>
R-R-4102	CB1 agonist 1 CAS No.851212-80-1	CB1 agonist 1 (compound 22)/CAS No.851212-80-1 is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders.	price>
R-C-2403	Atipamezole CAS:104054-27-5	Atipamezole(MPV-1248,MPV1248,Antisedan)is a synthetic α2 adrenergic receptor antagonist.It has also been researched in humans as a potential anti-Parkinsonian drug.	price>
R-R-4103	Taranabant racemate CAS No.701977-00-6	Taranabant racemate (MK-0364 racemate)/CAS No.701977-00-6 is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1.	price>
R-C-2404	Piribedil CAS:3605-01-4	Piribedil(Trivastal,Trivastan)is a relatively selective dopamine(D2/D3)agonist with moderate antidepressant activity.It also has α2-adrenergic(α2A/α2C)antagonist properties.	price>
R-R-4104	SCH 336 CAS No.447459-51-0	SCH 336/CAS No.447459-51-0 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice.	price>
R-C-2405	SR59230A CAS:174689-39-5	SR59230A is a blood-brain barrier penetrating,potent and selective antagonist of β3-adrenergic receptor with IC50 of 40nM,408nM,and 648nM for β3,β1,and β2 receptors,respectively.	price>
R-R-4105	Tetrahydromagnolol CAS No.20601-85-8	Tetrahydromagnolol (Magnolignan)/CAS No.20601-85-8, a main metabolite of Magnolol, is a potent and selective cannabinoid CB2 receptor agonist with an EC50 of 170 nM and a Ki of 416 nM. Tetrahydromagnolol possesses 20-fold more selective for CB2 receptor than CB1 receptor. Tetrahydromagnolol is also a weak GPR55 receptor antagonist.	price>
R-R-4106	AZD1940 CAS No.881413-29-2	AZD1940/CAS No.881413-29-2 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action.	price>
R-C-2407	Desvenlafaxine CAS:93413-62-8	Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor).It is being targeted as the first non-hormonal based treatment for menopause.Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters.	price>
R-R-4107	Vicasinabin CAS No.1433361-02-4	Vicasinabin (RG7774)/CAS No.1433361-02-4 is the potent agonist of cannabinoid receptor 2 (CB2). Vicasinabin has the potential for the research of human diseases including chronic pain, atherosclerosis, regulation of bone mass, neuroinflammation, and other related diseases (extracted from patent US20130116236A1).	price>
R-C-2408	Esmolol CAS:81147-92-4	Esmolol is a short acting hyperselective β-adrenergic blocker effective in blunting adrenergic response to several perioperative stimuli and so it might interfere in the effect of the anesthetic drugs on the brain.Esmolol is effective not only in attenuating intraoperative hemodynamic changes related to sympathetic overdrive but also in minimizing significant propofol and sevoflurane requirements without compromising the hemodynamic status.	price>
R-R-4108	LH21 CAS No.611207-11-5	LH-21/CAS No.611207-11-5 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats. , and displays efficacy as a feeding inhibitor.	price>
R-C-2409	Doxazosin CAS: 74191-85-8	Doxazosin(UK 33274)is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.	price>
R-R-4109	S-777469 CAS No.885496-53-7	S-777469/CAS No.885496-53-7 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism.	price>
R-C-2410	Nadolol CAS:42200-33-9	Nadolol(SQ-11725)is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2(OATP1A2).Nadolol has the the potential for high blood pressure,angina pectoris and vascular headaches research.	price>
R-R-4110	2-Arachidonoylglycerol-d8 CAS No.924894-97-3	2-Arachidonoylglycerol-d8/CAS No.924894-97-3 is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.	price>

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