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Catalog	name	Description	price
R-R-4161	CCR6 inhibitor 1 CAS No.2437547-04-9	CCR6 inhibitor 1/CAS No.2437547-04-9 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.	price>
R-C-2462	Pilocarpine HCl CAS：54-71-7	Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor(M3 muscarinic receptor)agonist.	price>
R-R-4162	AZD2098 CAS No.566203-88-1	AZD2098/CAS No.566203-88-1 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.	price>
R-C-2463	Nitenpyram CAS:150824-47-8	Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor(nAChR)agonist with an IC50 of 14nM.Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.	price>
R-R-4163	ZK756326 dihydrochloride CAS No.1780259-94-0	ZK756326 dihydrochloride/CAS No.1780259-94-0 is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.	price>
R-C-2464	LY2119620 CAS:886047-22-9	LY2119620 is a positive allosteric modulator of the M2 and M4 muscarinic acetylcholine receptors(mAChRs).	price>
R-R-4164	AZ084 CAS No.929300-19-6	AZ084/CAS No.929300-19-6 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer.	price>
R-C-2465	Cytisine CAS:485-35-8	Cytisine(Baphitoxine,Sophorine)is a nicotinic acetylcholine receptor agonist.	price>
R-R-4165	BX471 hydrochloride CAS No.288262-96-4	BX471 hydrochloride (ZK-811752 hydrochloride)/CAS No.288262-96-4 is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.	price>
R-C-2466	Choline Chloride CAS:67-48-1	Choline chloride is a quaternary ammonium salt used as an additive for animal feed.It is important as a precursor of acetylcholine,as a methyl donor in various metabolic processes,and in lipid metabolism.	price>
R-R-4166	R243 CAS No.688352-84-3	R243/CAS No.688352-84-3 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects.	price>
R-C-2467	Cevimeline CAS:153504-70-2	Cevimeline(AF-102B)is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist.Cevimeline stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia.Cevimeline can cross the blood-brain barrier(BBB).	price>
R-R-4167	GW 766994 CAS No.408303-43-5	GW 766994 (GW 994)/CAS No.408303-43-5 is a chemokine receptor-3 (CCR3) antagonist that is orally active and specific. GW 766994 has the potential for research into asthma and eosinophilic bronchitis.	price>
R-C-2468	Clozapine N-oxide CAS:34233-69-7	Clozapine N-oxide is a metabolite of clozapine(GLXC-06516),activating human muscarinic designer receptors(DREADDs)and suppressing food intake.	price>
R-R-4168	C-021 CAS No.864289-85-0	C-021/CAS No.864289-85-0 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.	price>
R-C-2469	Trospium chloride CAS:10405-02-4	Trospium chloride is an orally active,specific and competitive antagonist of muscarinic cholinergic receptors(mAChRs),with antimuscarinic activity.Trospium chloride binds to muscarinic receptors M1,M2 and M3 with high affinity,but not nicotinic,cholinergic receptors.	price>
R-R-4169	Tivumecirnon CAS No.2174938-78-2	Tivumecirnon (FLX475)/CAS No.2174938-78-2 is an orally active CCR4 antagonist that blocks regulatory T cells from entering the tumor microenvironment, thereby reducing their interference with effective anti-tumor immune responses. Tivumecirnon has antitumor activity.	price>
R-C-2470	Irsogladine CAS:57381-26-7	Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.	price>
R-R-4170	CCR2 antagonist 4 hydrochloride CAS No.1313730-14-1	CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride)/CAS No.1313730-14-1 is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM.	price>
R-C-2471	Carbaryl CAS:63-25-2	Carbaryl is a carbamate insecticide,commonly used to control aphids,fire ants, fleas,ticks,spiders,and many other outdoor pests.	price>

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