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Catalog	name	Description	price
R-R-4284	Plerixafor-d4 CAS No.1246819-87-3	Plerixafor-d4/CAS No.1246819-87-3 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM.	price>
R-C-2585	Melphalan CAS:148-82-3	Melphalan is a cytotoxic drug used to treat multiple myeloma.Phenylamine derivative of mechorethamine.	price>
R-R-4285	SB-332235 CAS No.276702-15-9	SB-332235/CAS No.276702-15-9 is a potent, orally active nonpeptide CXCR2 antagonist, with an IC50 of 7.7 nM. SB-332235 displays 285-fold selectivity for CXCR2 over CXCR1. SB-332235 inhibits acute and chronic models of arthritis in the rabbit. SB-332235 inhibits viability of AML cells.	price>
R-C-2586	Nolatrexed (AG-337) CAS:152946-68-4	Nolatrexed dihydrochloride(AG 337)is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme,with a Ki of 11nM for human thymidylate synthase.Nolatrexed dihydrochloride(AG 337)induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity.	price>
R-R-4286	CXCR2 antagonist 2 CAS No.2647464-91-1	CXCR2 antagonist 2/CAS No.2647464-91-1 is a potent CXCR2 antagonist for cancer immunoresearch with an IC50 value of 95 nM.	price>
R-C-2587	A-1210477 CAS:1668553-26-1	A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45nM. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner.	price>
R-R-4287	MPTP hydrochloride CAS No.23007-85-4	MPTP hydrochloride/CAS No.23007-85-4 is a brain-penetrating dopamine neurotoxin, inducing Parkinson disease. MPTP hydrochloride, precursor of MPP+, induces apoptosis.	price>
R-R-4288	Oxidopamine hydrochloride CAS No.28094-15-7	Oxidopamine (6-OHDA) hydrochloride/CAS No.28094-15-7 is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.	price>
R-C-2589	Piperlongumine CAS:20069-09-4	Piperlongumine is a alkaloid,possesses ant-inflammatory,antibacterial, antiangiogenic,antioxidant,antitumor,and antidiabetic activities.Piperlongumine induces ROS,and induces apoptosis in cancer cell lines.Piperlongumine shows anti-cardiac fibrosis activity,suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway.	price>
R-R-4289	SKF 81297 CAS No.71636-61-8	SKF 81297/CAS No.71636-61-8 is a potent and selective dopamine D1 receptor agonist.	price>
R-C-2590	mricasan (IDN-6556) CAS:254750-02-2	Emricasan(PF 03491390,IDN-6556)is an orally active and irreversible pan-caspase inhibitor.Emricasan inhibits Zika virus(ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors.	price>
R-R-4290	Fallypride CAS No.166173-78-0	Fallypride/CAS No.166173-78-0 is a potent antagonist of dopamine D2/D3 receptor. Fallypride, in the form of fallypride (18F), can be used as a positron emission tomography (PET) radiotracer.	price>
R-C-2591	GRI 977143 CAS:325850-81-5	GRI977143 is a selective lysophosphatidic acid 2(LPA2)receptor non-lipid agonist (EC50=3.3μM).GRI977143 does not activate other LPA GPCRs at concentrations up to 10μM.	price>
R-R-4291	Octoclothepin maleate salt CAS No.4789-68-8	Octoclothepin maleate salt/CAS No.4789-68-8, an orally active neuroleptic agent, is a dual SR-2A and D2DR inhibitor. Octoclothepin maleate salt reveals an intensive central depressant action in a series of observational and instrumental procedures in rodents.	price>
R-C-2592	AZ 10417808 CAS:331645-84-2	AZ 10417808 is a selective caspase-3 inhibitor with IC50 value of 14.9uM.AZ 10417808(AQZ-1)is a potent small molecule nonpeptidic inhibitor of caspase-3, which block cellular and biochemical features of apoptosis.	price>
R-R-4292	Clozapine N-oxide dihydrochloride CAS No.2250025-93-3	Clozapine N-oxide dihydrochloride/CAS No.2250025-93-3 is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.	price>
R-C-2593	Muristerone A CAS:38778-30-2	Muristerone A is a phytoecdysteroid analog of ecdysone which induces genes in mammalian cells and causes apoptosis in cells transfected with wild-type Bax.	price>
R-R-4293	SKF 38393 hydrochloride CAS No.62717-42-4	SKF 38393 hydrochloride/CAS No.62717-42-4 is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM.	price>
R-C-2594	SJ 172550 CAS:431979-47-4	SJ 172550 is the first MDMX inhibitor with EC50 of 0.84uM;binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.	price>
R-R-4294	Cabergoline CAS No.81409-90-7	Cabergoline/CAS No.81409-90-7 is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).	price>

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