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Catalog	name	Description	price
R-C-2926	PS-b-P4VP-b-PAA	The formation of block copolymer micelles depends on the attraction of hydrophobic end and the repulsion of hydrophilic end. According to the law of thermodynamics, when the surface free energy of the core-shell interface is smaller, the micelle is more stable. At this time, the micelle shrinks, the interfacial area shrinks, and the spatial repulsion force at the hydrophilic end increases; The interfacial tension and spatial repulsion restrict each other, so that the micelles can not aggregate or relax indefinitely to form a micellar system with stable particle size.	price>
R-R-4596	IMP-1088 CAS No.2059148-82-0	IMP-1088/CAS No.2059148-82-0 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a Kd of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection.	price>
R-C-2927	AC-TPE	Tetraphenylethylene molecules with strong fluorescence emission characteristics have attracted more and more research attention because of their wide application prospects in the fields of optoelectronic materials, biological detection, chemical sensing and so on.	price>
R-R-4597	CX-5461 dihydrochloride	CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).	price>
R-C-2928	Bilirubin-Polyethylene glycol-Sialic acid	Sialic acid is a derivative of 9-carbon monosaccharide, a negatively charged ion that can make saliva feel smooth. Polyethylene glycol has good water solubility and good miscibility with many organic components. They have excellent lubricity, moisture retention, dispersibility, adhesives, antistatic agents and softeners	price>
R-R-4598	Tirapazamine CAS No.27314-97-2	Tirapazamine (SR259075)/CAS No.27314-97-2 is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells.	price>
R-C-2929	PEI-Ortho bromophenylboronic acid	Polyethyleneimine has high reaction activity, can react with hydroxyl groups in cellulose and crosslink polymerization, so as to produce wet strength of paper. The presence of any acid, alkali and aluminum sulfate will affect its wet strength and retention.	price>
R-R-4599	RP-6685 CAS No.2832047-80-8	RP-6685/CAS No.2832047-80-8 is a potent, selective and orally active DNA polymerase theta (Polθ) inhibitor with an IC50 value of 5.8 nM (PicoGreen assay). RP-6685 shows antitumor efficacy in mouse tumor xenograft model. RP-6685 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4600	D-I03 CAS No.688342-78-1	D-I03/CAS No.688342-78-1 is a selective RAD52 inhibitor with a Kd of 25.8 µM. D-I03 specifically inhibits RAD52-dependent single-strand annealing (SSA) and D-loop formation with IC50s of 5 µM and 8 µM, respectively. D-I03 suppresses growth of BRCA1- and BRCA2-deficient cells and inhibits formation of damage-induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin.	price>
R-C-2931	FITC modified silica nanoparticles（50nm）	FITC modified silica nanoparticles, green fluorescence, particle size 50 nm, dispersed in ultrapure water. 5mg/ml.	price>
R-R-4601	Quarfloxin CAS No.865311-47-3	Quarfloxin (CX-3543)/CAS No.865311-47-3, a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template.	price>
R-C-2932	Mesoporous silica supported dihydroporphyrin E6	Recent advancements in morphology control and surface functionalization of mesoporous silica nanoparticles (MSNs) have enhanced the biocompatibility of these materials with high surface areas and pore volumes. The functionalization of MSNs with organic moieties or other nanostructures brings controlled release and molecular recognition capabilities to these mesoporous materials for drug/gene delivery and sensing applications, respectively.	price>
R-R-4602	Nusinersen CAS No.1258984-36-9	Nusinersen/CAS No.1258984-36-9 is an antisense oligonucleotide agent that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein.The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Nusinersen sodium) that retains the same biological activity.	price>
R-C-2933	Ir(bt)2(acac)	Our company sells research regeats related to nano targeted drug delivery system, including synthetic phospholipid, polyethylene glycol derivatives, block copolymers, gold nanoparticles, magnetic nanoparticles and fluorescent dyes.	price>
R-R-4603	GS-443902 trisodium CAS No.1355050-21-3	GS-443902 trisodium (GS-441524 triphosphate trisodium)/CAS No.1355050-21-3 is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734).	price>
R-C-2934	cDots-PEG1K-NH2	Quantum dots are semiconductor nanostructures that bind excitons in three spatial directions. The emission spectrum of quantum dots can be controlled by changing the size of quantum dots.	price>
R-R-4604	Fidaxomicin CAS No.873857-62-6	Fidaxomicin (OPT-80)/CAS No.873857-62-6, a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research.	price>
R-C-2935	SiO2 coating Fe3O4 nanoparticles（30nm）	Fe3O4 nanoparticles are widely used in immunosensors, biological missiles, DNA isolation and transfection,gene carriers for tumor gene therapy, in vivo drug targeted delivery systems,in vivo controlled-release drug delivery systems, biocatalysis and medical diagnosis.The biocompatibility, stability and dispersion of {Fe3O4 nanoparticles were better after SiO2 coating. This product is 30nm Fe3O4@SiO2 Core-shell nanoparticles.	price>
R-R-4605	Cytarabine hydrochloride CAS No.69-74-9	Cytarabine hydrochloride/CAS No.69-74-9, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.	price>
R-C-2936	FITC-SiO2（70nm）	Green fluorescein FITC labeled mesoporous silica coated magnetic nanoparticles. The large pore size of these products can be used for drug carrier, FITC fluorescent can be used for fluorescence tracking imaging, cell sorting, magnetic targeted hyperthermia, magnetic particle contrast agent, etc. they belong to dual imaging nano materials.	price>

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