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R-R-4616 PTC299 CAS No.1256565-36-2 PTC299/CAS No.1256565-36-2 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies. price>
R-C-2947 α-Cyclodextrin-PEI With heel β- At the same time, due to the better water solubility of simple a-cyclodextrin, the solubility of a-cyclodextrin is 12.7g/100ml water at room temperature of 25 ° C, while that of b-cyclodextrin is only 1.88g/100ml water. Therefore, it has a wider application range. PEI can choose branch or linear. price>
R-R-4617 RG7800 CAS No.1449598-06-4 RG7800/CAS No.1449598-06-4 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment. price>
R-C-2948 β-Cyclodextrin methylethers-Dextran MW:500K Amino acid modified cyclodextrins are used to study molecular recognition, the essence of inclusion and molecular self-assembly Using L-arginine and mono - (6-o-p-toluenesulfonyl)- β- Amino acid modified was synthesized by the reaction of cyclodextrin β- Cyclodextrin price>
R-R-4618 DHX9-IN-2 CAS No.2973395-71-8 DHX9-IN-2 (example 31)/CAS No.2973395-71-8 is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the IC50 of 0.0698 nM that has antitumor activity. price>
R-C-2949 PAMAM G1-NH2 PAMAM is a polyamide amine dendrimer with colorless to yellowish transparent liquid.As a carrier of drugs,genes and vaccines in the field of biomedicine,it is used for drug sustained-release and targeted release;it is used for in-vitro diagnosis,in vitro gene transfer,gene therapy,nuclear magnetic resonance imaging and other applications. price>
R-R-4619 JH-RE-06 CAS No.1361227-90-8 JH-RE-06/CAS No.1361227-90-8, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy. price>
R-C-2950 PAMAM G2-NH2 PAMAM is a polyamide amine dendrimer with colorless to yellowish transparent liquid.As a carrier of drugs,genes and vaccines in the field of biomedicine,it is used for drug sustained-release and targeted release;it is used for in-vitro diagnosis,in vitro gene transfer,gene therapy,nuclear magnetic resonance imaging and other applications. price>
R-R-4620 Zoliflodacin CAS No.1620458-09-4 Zoliflodacin (ETX0914;AZD0914)/CAS No.1620458-09-4 is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL. price>
R-C-2951 PAMAM G3-NH2 PAMAM is a polyamide amine dendrimer with colorless to yellowish transparent liquid.As a carrier of drugs,genes and vaccines in the field of biomedicine,it is used for drug sustained-release and targeted release;it is used for in-vitro diagnosis,in vitro gene transfer,gene therapy,nuclear magnetic resonance imaging and other applications. price>
R-R-4621 116-9e CAS No.831217-43-7 116-9e (MAL2-11B)/CAS No.831217-43-7 is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. price>
R-C-2952 Poly-L-lysine (MW:20-40k) ε- Polylysine is polymerized from 25 ~ 30 lysine residues. It has strong antibacterial ability and can be used as a preservative for food preservation. ε- Polylysine has a wide antibacterial spectrum and has a certain antibacterial effect on Gram-positive bacteria, Gram-negative bacteria, yeasts and molds in acidic and slightly acidic environment. price>
R-R-4622 DDD85646 CAS No.1215010-55-1 DDD85646 (IMP-366)/CAS No.1215010-55-1 is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis. price>
R-C-2953 Gamma-PGA MW:20-40k Gamma PGA is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 100~1000 kDa. price>
R-R-4623 Fialuridine CAS No.69123-98-4 Fialuridine/CAS No.69123-98-4 is a nucleoside analog with antiviral activity. Fialuridine shows anti-orthopoxvirus activity. price>
R-C-2954 Oligoarginine-FITC Labeled Isothiocyanate fluorescent orange red,isothiocyanate fluorescent yellow,isothiocyanate fluorescent red, isothiocyanate fluorescein isomer I, 5-isothiocyanate fluorescein. Its form is yellow powder with hygroscopicity. It is a biochemical reagent. price>
R-R-4624 L82 CAS No.329227-30-7 L82/CAS No.329227-30-7 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells price>
R-C-2955 Oligoarginine-TAMRA Labeled RuixiBiotechCo.Ltd sells research regeats related to nano targeted drug delivery system, including synthetic phospholipid, polyethylene glycol derivatives, block copolymers, gold nanoparticles, magnetic nanoparticles and fluorescent dyes. price>
R-R-4625 COH29 CAS No.1190932-38-7 COH29 (RNR Inhibitor COH29)/CAS No.1190932-38-7 is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50s of 16 μM. price>
R-R-4626 L189 CAS No.64232-83-3 L189/CAS No.64232-83-3 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer. price>