Xi'an ruixi Biological Technology Co

Home > Keywords >

Catalog	name	Description	price
R-R-4637	Hycanthone CAS No.3105-97-3	Hycanthone/CAS No.3105-97-3 is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.	price>
R-C-2968	SB271046 CAS：209481-20-9	SB271046 is a potent,selective and orally active 5-HT6 receptor antagonist with pKi of 8.9,exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.	price>
R-R-4638	Branaplam hydrochloride CAS No.1562338-39-9	Branaplam (LMI070; NVS-SM1) hydrochloride/CAS No.1562338-39-9 is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model	price>
R-C-2969	SB269652 CAS：215802-15-6	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor(D2R).SB269652 binds in a bitopic manner at one protomer of a D2R dimer and modulates the binding of dopamine at a second protomer.	price>
R-R-4639	Galidesivir CAS No.249503-25-1	Galidesivir (BCX4430)/CAS No.249503-25-1, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM.	price>
R-C-2970	SB-277011 CAS：215803-78-4	SB-277011 is a drug which acts as a potent and selective dopamine D3 receptor antagonist which is around 80-100x selective for D3 over D2 and lacks any partial agonist activity.	price>
R-R-4640	Gemifloxacin mesylate CAS No.210353-53-0	Gemifloxacin mesylate (SB-265805S; LB-20304a)/CAS No.210353-53-0 is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.	price>
R-C-2971	Lumiracoxib CAS:220991-20-8	Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Only for scientific research, not for human body.	price>
R-R-4641	AG-636 CAS No.1623416-31-8	AG-636/CAS No.1623416-31-8 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. AG-636 has strong anticancer effects.	price>
R-R-4642	BCH001 CAS No.384859-58-9	BCH001/CAS No.384859-58-9, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging.	price>
R-C-2973	Adoprazine (SLV313) CAS:222551-17-9	Adoprazine,also known as SLV313,is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug. Adoprazine is part of the Antidepressant Agent group.Only for scientific research, not for human body.	price>
R-R-4643	Braco-19 CAS No.351351-75-2	Braco-19/CAS No.351351-75-2 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-C-2974	NPS 2390 CAS:226878-01-9	NPS2390 is a group I mGlu antagonist. It displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket.Only for scientific research, not for human body.	price>
R-R-4644	Dithranol CAS No.1143-38-0	Dithranol (Anthralin)/CAS No.1143-38-0 is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair.	price>
R-C-2975	Lofepramine CAS# 23047-25-8	Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535).Only for scientific research, not for human body.	price>
R-R-4645	Ethynylcytidine CAS No.180300-43-0	Ethynylcytidine (ECyD)/CAS No.180300-43-0, a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-2976	PD 102807 CAS:23062-91-1	PD 102807 is an m4 muscarinic receptor antagonist with an IC50 of 90.7 nm.PD 102807 inhibited M1,M2,m3 and M5 muscarinic receptors with IC50 of 6558.7,3440.7,950.0 and 7411.7nm, respectively. It has the effect of anti dyskinesia.Only for scientific research, not for human body.	price>
R-R-4646	TTP-8307 CAS No.950225-08-8	TTP-8307/CAS No.950225-08-8 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP).	price>
R-C-2977	Bay 36-7620 CAS:232605-26-4	Selective mGlu1 receptor non-competitive antagonist (IC50 = 0.16 μM) with inverse agonist activity. Impairs classical conditioning and associated synaptic plasticity in hippocampal neurons. Exhibits neuroprotective and anticonvulsive effects in vivo following systemic administration.Only for scientific research, not for human body.	price>
R-R-4647	Neobavaisoflavone CAS No.41060-15-5	Neobavaisoflavone/CAS No.41060-15-5, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation.	price>

669670671672673674 675676677678679