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Catalog	name	Description	price
R-R-4648	BRD32048 CAS No.433694-46-3	BRD32048/CAS No.433694-46-3 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen.	price>
R-R-4649	Cinoxacin CAS No.28657-80-9	Cinoxacin (Compound 64716)/CAS No.28657-80-9, a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.	price>
R-R-4650	Deoxyguanosine triphosphate trisodium salt CAS No.93919-41-6	Deoxyguanosine triphosphate (dGTP) trisodium salt/CAS No.93919-41-6 is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.	price>
R-R-4651	Braco-19 trihydrochloride CAS No.1177798-88-7	Braco-19 trihydrochloride/CAS No.1177798-88-7 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-R-4652	NVS-SM2 CAS No.1562333-92-9	NVS-SM2/CAS No.1562333-92-9 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research.	price>
R-R-4653	ERCC1-XPF-IN-2 CAS No.1808986-37-9	ERCC1-XPF-IN-2/CAS No.1808986-37-9 is a potent ERCC1-XPF endonuclease inhibitor with an IC50 value of 0.6 µM. ERCC1-XPF-IN-2 shows activity in nucleotide excision repair, cisplatin enhancement and γH2AX assays.	price>
R-C-2984	Ro 28-1675 CAS:300353-13-3	Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24,0.0019 uM.Only for scientific research, not for human body.	price>
R-R-4654	Anticancer agent 73 CAS No.124811-87-6	Anticancer agent 73 (compound CIB-3b)/CAS No.124811-87-6 is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo.	price>
R-C-2985	PF-07321332 cas:2628280-40-8	PF-07321332(Paxlovid)is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. Only for scientific research, not for human body.	price>
R-R-4655	L82-G17 CAS No.92285-87-5	L82-G17/CAS No.92285-87-5 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity.	price>
R-C-2986	Ro5-3335 CAS# 30195-30-3	Ro5-3335 is a benzodiazepine compound, which can be used as a core binding factor (CBF) leukemia inhibitor. Ro5-3335 is runx1-cbf β Interaction inhibitors can inhibit Runx1 / CBFB dependent trans activation. Only for scientific research, not for human body.	price>
R-R-4656	PCNA-I1 CAS No.444930-42-1	PCNA-I1/CAS No.444930-42-1 is a potent PCNA (proliferating cell nuclear antigen) inhibitor. PCNA-I1 directly binds PCNA trimers with a Kd of 0.41 μM and exhibits antitumor activity both in vitro and in vivo.	price>
R-C-2987	RO-9187 CAS:876708-03-1	Ro-9187 is a highly effective HCV replication inhibitor with an IC50 value of 171 nm. Only for scientific research, not for human body.	price>
R-R-4657	CP681301 CAS No.865317-32-4	CP681301/CAS No.865317-32-4 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila.	price>
R-C-2988	RO4929097 CAS:847925-91-1	RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.Only for scientific research,not for human body.	price>
R-R-4658	b-Amanitin CAS No.21150-22-1	β-Amanitin/CAS No.21150-22-1 is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs).	price>
R-C-2989	DDAO,CAS:118290-05-4	DDAO is a potential near infrared (NIR) red fluorescent probe with adjustable excitation wavelength (600-650   nm) and long emission wavelength（ λ em = 656 nm).DDAO can be used to detect the activities of different enzymes, such as β- Galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.Only for scientific research, not for human body.	price>
R-R-4659	Lomibuvir CAS No.1026785-55-6	Lomibuvir (VX-222)/CAS No.1026785-55-6, a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.	price>
R-C-2990	U0126-EtOH CAS:1173097-76-1	U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. This inhibition of MEK1/2 is noncompetitive with ERK and ATP.Only for scientific research, not for human body.	price>
R-R-4660	Clevudine CAS No.163252-36-6	Clevudine (L-FMAU)/CAS No.163252-36-6, a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice.	price>

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