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Catalog | name | Description | price |
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R-R-4688 | H3B-968 CAS No.2912294-90-5 | H3B-968/CAS No.2912294-90-5 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM),which acts function as helicase,ATPase,and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However,H3B-968 inhibits WRN helicase activity,competitively with ATP. | price> |
R-R-4689 | Pseudouridimycin CAS No.1566586-52-4 | Pseudouridimycin (PUM)/CAS No.1566586-52-4, an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. | price> |
R-R-4690 | 6-Hydroxy-DOPA CAS No.21373-30-8 | 6-Hydroxy-DOPA/CAS No.21373-30-8 is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer. | price> |
R-R-4691 | 5-Propargylamino-dCTP CAS No.115899-39-3 | 5-Propargylamino-dCTP/CAS No.115899-39-3 is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
R-R-4692 | (2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate CAS :864163-80-4 | (2,2-Bipyridine)bis[2-(2,4-difluorophenyl)pyridine]iridium(III) Hexafluorophosphate/CAS :864163-80-4 is a coordination complex featuring an iridium(III) ion at its core. The complex is comprised of 2,2-bipyridine ligands and two 2-(2,4-difluorophenyl)pyridine ligands that coordinate with the iridium ion. The hexafluorophosphate anion (PF₆⁻) is included in the compound to balance the charge of the iridium center.This complex is known for its luminescent properties and finds applications in fields such as organic light-emitting diodes (OLEDs), where the unique photophysical characteristics of the iridium center play a crucial role in light emission processes. The presence of the difluorophenyl groups in the ligands can influence the complex emission wavelengths and efficiency, contributing to its potential in optoelectronic devices.The combination of the bipyridine and difluorophenylpyridine ligands around the iridium ion results in a specific coordination environment that influences the complex stability, reactivity, and optical properties. | price> |
R-R-4693 | Ir(p-CF3-ppy)3 CAS No:500295-52-3 | Ir(p-CF3-ppy)3/CAS No:500295-52-3 is a new type of organometallic compound. It has been shown to be useful for the formation of bioactive molecules, such as linear and hydrogenated aromatic compounds, thioethers, and chlorinated bonds. This compound can also catalyze bond formations, radical reactions, and fluorination reactions. Ir(p-CF3-ppy)3 has also been studied as a photocatalyst in the functionalization of organic molecules. | price> |
R-R-4694 | tert-Butyl ((1R,2R)-2-amino-3,3-difluorocyclohexyl)carbamate CAS No:1109284-37-8 | tert-Butyl ((1R,2R)-2-amino-3,3-difluorocyclohexyl)carbamate/CAS No:1109284-37-8 is a chemical compound. This chemical compound may have applications in organic synthesis, medicinal chemistry, or as a building block for more complex molecules. The presence of the difluorocyclohexyl group and the carbamate functionality imparts specific properties to the compound which can be utilized in various chemical processes or as a structural component in the synthesis of bioactive compounds. | price> |
R-C-3025 | PF-4989216 CAS:1276553-09-3 | PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Only for scientific research, not for human body. | price> |
R-R-4695 | Biotin-TEG-NH2 TFA CAS No:1334172-59-6 | Biotin-TEG-NH2 TFA/N-Biotin-tetra(ethylene glycol)-diamine trifluoroacetate/CAS No:1334172-59-6 is a chemical compound that consists of biotin (a vitamin B7 derivative) linked to an amino group (NH2) through a TEG (triethylene glycol) spacer, with a trifluoroacetic acid (TFA) counterion. Biotin-TEG-NH2 TFA is a versatile compound used in biochemistry, molecular biology, and biotechnology for applications such as protein labeling, protein detection, and immunoassays due to its biotin-streptavidin interaction and its potential for functionalization through the amino group. | price> |
R-C-3026 | AZD8835 cas:1620576-64-8 | AZD8835 is a potent inhibitor of PI3Kα (wild type, E545K and H1047R mutations) and PI3Kδ with excellent selectivity vs. PI3Kβ, PI3Kγ and an excellent general kinase selectivity.Only for scientific research, not for human body. | price> |
R-R-4696 | Bis-dPEG5-PFP ester CAS No:1334177-78-4 | Bis-dPEG5-PFP ester/Bis(perfluorophenyl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate/CAS No:1334177-78-4 is a halogenated PEG (polyethylene glycol) compound that is used in various applications. It is a homobifunctional PEG with two fluorinated phenyl groups attached to the PEG backbone. This unique structure provides enhanced stability and hydrophobicity, making it ideal for use in drug delivery systems, surface modifications, and bioconjugation reactions. The fluorophenyl groups of Bis-dPEG5-PFP ester offer excellent reactivity towards nucleophiles, allowing for efficient conjugation with biomolecules such as proteins, peptides, and antibodies. Its high purity and low polydispersity ensure consistent results in each application. With its fluorine-containing moieties, Bis-dPEG5-PFP ester can also be utilized as a labeling agent for imaging purposes. The presence of fluorine atoms enables easy detection and tracking of labeled compounds using techniques like fluorine-19 magnetic resonance imaging (19F MRI). | price> |
R-C-3027 | TGR-1202 (Umbralisib) CAS:1532533-67-7 | Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.Only for scientific research, not for human body. | price> |
R-R-4697 | 6-Fluoro-6-deoxy-D-galactose CAS No:4536-07-6 | 6-Fluoro-6-deoxy-D-galactose (FDG)/CAS No:4536-07-6 is a fluorinated sugar. FDG has been shown to inhibit the uptake of glucose by l1210 murine cells, as well as the transport of glucose into the cell. It also inhibited cell culture and enzyme activities in human liver tissue. The electron microscopic analysis of cytochalasin B and trifluoroacetic acid treated cells showed that FDG disrupts the microtubule network, leading to inhibition of cellular proliferation. FDG has also been found to inhibit the synthesis of DNA and RNA in L5178 murine lymphoma cells. | price> |
R-C-3028 | GDC-0326 CAS:1282514-88-8 | GDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.Only for scientific research, not for human body. | price> |
R-R-4698 | 1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose CAS No:444586-86-1 | 1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose/CAS No:444586-86-1 is a sugar that is modified with fluorine. It has been synthesized using the "click" reaction methodology and is available for custom synthesis. This synthetic sugar can be used in glycosylation reactions or as a monosaccharide or polysaccharide in complex carbohydrate click chemistry. This product is of high purity and can be modified with methyl groups or other functional groups to suit your needs. | price> |
R-C-3029 | acalisib (GS-9820) CAS:870281-34-8 | Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.Only for scientific research, not for human body. | price> |
R-R-4699 | 4-Chloromethyl-6,8-difluoroumbelliferyl b-D-galactopyranoside CAS No:215868-46-5 | 4-Chloromethyl-6,8-difluoroumbelliferyl b-D-galactopyranoside/CAS No:215868-46-5 is a compound commonly used in biochemical research as a fluorescent substrate for the detection of sugar hydrolase enzymes. This compound can be cleaved by enzymes such as β-galactosidase, releasing a fluorescent molecule that can be easily detected using fluorescence spectroscopy. The compound is a member of the family of umbelliferyl glycosides, which have been widely used in the study of various biochemical pathways for many years. The advantage of using this particular substrate is that the fluorescent product has a high quantum yield, which means it produces a strong signal for detection. This substrate has been used in a wide variety of applications, including the study of microbial physiology and in the development of diagnostic assays for detecting bacterial and fungal infections. | price> |
R-C-3031 | AMG 511 CAS:1253573-53-3 | AMG 511 is a potent and selective pan class I PI3K inhibitor, capable of inhibiting PI3K signaling and inducing robust anti-proliferative effects via a G1 arrest in many tumor cell lines, with evidence of cell killing in a subset of lines.Only for scientific research, not for human body. | price> |
R-R-4700 | 6,8-Difluoro-4-methylumbelliferyl b-D-glucopyranoside CAS:351009-26-2 | 6,8-Difluoro-4-methylumbelliferyl b-D-glucopyranoside/CAS:351009-26-2 is a versatile fluorogenic substrate suitable for the measurement of various glycosidase enzymes. Its unique structure allows for enhanced sensitivity and selectivity in enzyme assays, making it ideal for studying enzyme kinetics and screening of potential enzyme inhibitors. | price> |
R-R-4701 | 6-Fluoro-3-indoxyl-beta-D-galactopyranoside CAS No:207727-11-5 | 6-Fluoro-3-indoxyl-beta-D-galactopyranoside/CAS No:207727-11-5 is a fluorescent chromogenic substrate that is commonly used for the detection and quantification of beta-galactosidase activity. When this substrate is hydrolyzed by beta-galactosidase, it produces a fluorescent blue product that can be easily detected and measured using a fluorometer or spectrophotometer. This substrate is often used in microbiology and molecular biology research to study gene expression and enzyme kinetics, and is also used in medical diagnostics as a marker for specific diseases and conditions. | price> |