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R-C-3055 WYE-687 CAS: 1062161-90-3 WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold). price>
R-R-4725 1,1,1-Trifluoroethyl-PEG4-aminooxy CAS: 1895922-78-7 1,1,1-Trifluoroethyl-PEG4-aminooxy/CAS: 1895922-78-7 is a fluorine containing PEG molecule. The aminooxy group can be used in bioconjugation and It reacts with an aldehyde to form an oxime bond. price>
R-C-3056 WYE-354  CAS:1062169-56-5 WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold). price>
R-R-4726 Octakis-(6-bromo-6-deoxy)-y-cyclodextrin CAS No.53784-84-2 Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin/CAS No.53784-84-2 is a perbrominated γ-cyclodextrin at the primary side. Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is also a commonly used intermediate in the modification of cyclodextrin. price>
R-C-3057 Ridaforolimus (Deforolimus, MK-8669) CAS:572924-54-0 Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line. price>
R-R-4727 Heptakis(2,3,6-tri-O-benzoyl)-b-cyclodextrin CAS No.23666-43-5 Heptakis(2,3,6-tri-O-benzoyl)-β-cyclodextrin/CAS No.23666-43-5 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3058 Paeoniflorin (NSC 178886) CAS:23180-57-6 Paeoniflorin (NSC 178886) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway. price>
R-R-4728 Mono-2-O-(p-toluenesulfonyl)-a-cyclodextrin CAS No.93184-10-2 Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin/Mono-2-o-(p-toluenesulfonyl)-alpha-cyclodextrin/CAS No.93184-10-2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3059 HUN86320 CAS:882286-32-0 TSPC is an inhibitor for GA perception by in vitro and in planta evaluations. price>
R-R-4729 Mono-2-O-(p-toluenesulfonyl)-y-cyclodextrin CAS No.97227-32-2 Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin/Mono-2-O-(p-toluenesulfonyl)-gamma-cyclodextrin/CAS No.97227-32-2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3060 BRD3731 cas:2056262-07-6 BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. BRD3731 inhibits the phosphorylation of CRMP2 in SH-SY5Y cells. BRD3731 decreases β-catenin S33/37/T41 phosphorylation and induces β-catenin S675 phosphorylation in HL-60 cells. BRD3731 impairs colony formation in TF-1 and increases colony forming ability in the MV4-11 cell line. price>
R-R-4730 Mono-6-O-(p-toluenesulfonyl)-a-cyclodextrin CAS No.97227-32-2 Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin/Mono-6-O-(p-toluenesulfonyl)-alpha-cyclodextrin/CAS No.97227-32-2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3061 BRD3308 CAS:1550053-02-5 BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. price>
R-R-4731 Mono-6-O-mesitylenesulfonyl-y-cyclodextrin CAS No.174010-62-9 Mono-6-O-mesitylenesulfonyl-γ-cyclodextrin/CAS No.174010-62-9 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3062 BRD0705 CAS:2056261-41-5 BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor. price>
R-R-4732 Mono-6-O-(p-toluenesulfonyl)-y-cyclodextrin CAS No.97227-33-3 Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3063 SB415286 CAS: 264218-23-7 SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β. SB415286 causes MM cell growth arrest and apoptosis. price>
R-R-4733 Hexakis (2,3,6-tri-O-methyl)-a-cyclodextrin CAS No.68715-56-0 Hexakis (2,3,6-tri-O-methyl)-α-cyclodextrin/Hexakis (2,3,6-tri-O-methyl)-alpha-cyclodextrin/CAS No.68715-56-0 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
R-C-3064 LY2090314  CAS:603288-22-8 LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases. price>
R-R-4734 Heptakis(2,3,6-tri-O-ethyl)-b-cyclodextrin CAS No.111689-01-1 Heptakis(2,3,6-tri-O-ethyl)-β-cyclodextrin/CAS No.111689-01-1 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. price>
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