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Catalog	name	Description	price
R-C-3065	BX517 CAS:850717-64-5	BX517 is a potent and selective inhibitor of PDK1 that binds to the ATP binding pocket of the protein (IC50 = 6 nM).	price>
R-R-4735	Heptakis-(2,6-di-O-ethyl)-b-cyclodextrin CAS No.111689-03-3	Heptakis-(2,6-di-O-ethyl)-β-cyclodextrin/DE-beta-Cyd/CAS No.111689-03-3 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.	price>
R-C-3066	GSK2334470 CAS:1227911-45-6	GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM in a cell-free assay, with no activity at other close related AGC-kinases.Only for scientific research, not for human body.	price>
R-R-4736	Maltooctaose CAS No.66567-45-1	Maltooctaose/CAS No.66567-45-1, a specific-length maltooligosaccharide, can be produced by PFTA (Pyrococcus furiosus).	price>
R-C-3067	SL-0101-1 cas:77307-50-7	SL 0101-1 is a selective p90 ribosomal S6 kinase (RSK) inhibitor for RSK2 with an IC50 of 89 nM. The IC50 of kaempferol, the flavonoid constituent of SL 0101-1, is 15 μM for RSK. The rhamnose moiety of SL 0101-1 increases the affinity for RSK by >150-fold. Only for scientific research, not for human body.	price>
R-R-4737	HBV-IN-4 CAS No.2305897-84-9	HBV-IN-4/CAS No.2305897-84-9, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 induces the formation of genome-free capsids and has potent anti-HBV potencies.	price>
R-C-3068	BI-D1870 CAS:501437-28-1	BI-D1870 is a potent and specific inhibitor of the p90 ribosomal S6 kinase (RSK) isoforms in vitro and in vivo, which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 10–30 nM.Only for scientific research, not for human body.	price>
R-R-4738	Sodium Camptothecin CAS No.25387-67-1	Sodium Camptothecin/CAS No.25387-67-1 is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.	price>
R-C-3069	IM156 CAS: 1422365-93-2	IM156 (HL156A), a metformin derivative, is a potent activator of AMPK that increases AMPK phosphorylation. IM156 blocks oxidative phosphorylation (OXPHOS) through the inhibition of complex I and increases apoptosis. IM156 ameliorates various types of fibrosis and inhibits tumors.Only for scientific research, not for human body.	price>
R-R-4739	2-(Methylamino)-1H-purin-6(7H)-one CAS No.10030-78-1	2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine)/CAS No.10030-78-1 is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.	price>
R-C-3070	MK-3903 CAS：1219737-12-8	MK-3903 is a potent and selective AMPK activator with an EC50 of 8 nM for α1 β1 γ1 subunit. It activates 10 of the 12 pAMPK complexes with EC50 values in the range of 8-40 nM and maximal activation >50%.Only for scientific research, not for human body.	price>
R-R-4740	Thymidine-d4 CAS No.347841-67-2	Thymidine-d4/CAS No.347841-67-2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.	price>
R-C-3071	PF-06409577 CAS:1467057-23-3	PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.Only for scientific research, not for human body.	price>
R-R-4741	Sterigmatocystine CAS No.10048-13-2	Sterigmatocystine/CAS No.10048-13-2 is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.	price>
R-C-3072	OTSSP167 CAS:1431697-89-0	OTSSP167 (OTS167) is a highly potent MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.Only for scientific research, not for human body.	price>
R-R-4742	DHPS-IN-1 CAS No.2643300-54-1	DHPS-IN-1/CAS No.2643300-54-1, with the best DHPS inhibitory potency (IC50 = 0.014 μM), exhibits excellent inhibition against melanoma cells.	price>
R-C-3073	YU238259 CAS:1943733-16-1	YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.Only for scientific research, not for human body.	price>
R-R-4743	Filibuvir CAS No.877130-28-4	Filibuvir/CAS No.877130-28-4 is an orally active, selective non-nucleoside inhibitor of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase (RdRp). Filibuvir binds noncovalently in the thumb II allosteric pocket of NS5B. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM for both isoforms, respectively. Filibuvir preferentially inhibits elongative RNA synthesis and potently decreases viral RNA accumulation.	price>
R-C-3074	LTURM34 CAS:1879887-96-3	LTURM34 is a specific DNA-PK inhibitor, 170-fold more selective for DNA-PK activity compared to PI3K activity, with IC50 value of 0.034 μM.Only for scientific research, not for human body.	price>
R-R-4744	SMN-C2 CAS No.1446311-56-3	SMN-C2/CAS No.1446311-56-3, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research.	price>

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