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Catalog	name	Description	price
R-C-3095	CP-547632 CAS:252003-65-9	CP-547632 is a novel, potent vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor.Only for scientific research, not for human body.	price>
R-R-4765	Methotrexate-d3 CAS No.432545-63-6	Methotrexate-d3 (Amethopterin-d3)/CAS No.432545-63-6 is the deuterium labeled Methotrexate. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).	price>
R-C-3096	CP-673451 CAS:343787-29-1	CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity.Only for scientific research, not for human body.	price>
R-R-4766	7-Iodo-2,3-dideoxy-7-deaza-guanosine CAS No.114748-67-3	7-Iodo-2,3-dideoxy-7-deaza-guanosine/CAS No.114748-67-3 is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions.	price>
R-C-3097	Lucitanib(E-3810) CAS:1058137-23-7	Lucitanib , also known as E-3810 and AL3810, is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death.	price>
R-R-4767	DNA31 CAS No.845626-57-5	DNA31/CAS No.845626-57-5 is a potent RNA polymerase inhibitor.	price>
R-C-3098	Aftin-4 CAS# 866893-90-5	Aftin-4 is an amyloid-β42 inducer that electively and potently increases production of extracellular Aβ42 and decreases production of extracellular Aβ38 in cultured cells.	price>
R-R-4768	ZIM CAS No.301298-87-3	ZIM/CAS No.301298-87-3, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research.	price>
R-R-4769	WRN inhibitor 3 CAS No.2923009-48-5	WRN inhibitor 3 (example 110)/CAS No.2923009-48-5, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer.	price>
R-R-4770	5-Methylcytosine-d4 CAS No.1219795-15-9	5-Methylcytosine-d4/CAS No.1219795-15-9 is the deuterium labeled 5-Methylcytosine. 5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development.	price>
R-C-3101	TAK-981 CAS:1858276-04-6	TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.	price>
R-R-4771	BVDV-IN-1 CAS No.345651-04-9	BVDV-IN-1/CAS No.345651-04-9 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).	price>
R-C-3102	N106 CAS:862974-25-2	N106,activator of SUMO-activating enzyme,E1 ligase.Increases SERCA2a SUMOylation and activity,and enhances contractility in rat cardiomyocytes in vitro.	price>
R-R-4772	Remdesivir nucleoside monophosphate CAS No.1911578-74-9	Remdesivir nucleoside monophosphate/CAS No.1911578-74-9 is a metabolite of Remdesivir. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV.	price>
R-C-3103	COH000 CAS:1534358-79-6	COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.	price>
R-R-4773	Thiarabine CAS No.26599-17-7	Thiarabine (OSI-7836)/CAS No.26599-17-7 shows potent anti-tumor activity and inhibition of DNA synthesis.	price>
R-C-3104	PYR-41 CAS:418805-02-4	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.PYR-41 induce apoptosis.	price>
R-R-4774	Holomycin CAS No.488-04-0	Holomycin/CAS No.488-04-0 is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis.	price>
R-C-3105	BAY 11-7082 (BAY 11-7821) CAS:19542-67-7	BAY 11-7082(BAY 11-7821)is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM,respectively.BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.	price>
R-R-4775	2-Deoxyadenosine 5-di-phos-phate disodium CAS No.72003-83-9	2-Deoxyadenosine 5-di-phos-phate disodium (dADP disodium)/CAS No.72003-83-9 is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes.	price>

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