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| Catalog | name | Description | price |
|---|---|---|---|
| R-C-3987 | sucrose-PEG750-DSPE | DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Sucrose,organic compound,molecular weight 342.3.Colorless crystal,with optical rotation,but no variable rotation. | price> |
| R-R-5667 | DT-061 (SMAP) Liposomes, Formulation TT-40 | DT-061 (SMAP) Liposomes, Formulation TT-40. PEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. | price> |
| R-M-1545 | Acetyl-ccβ | The ccβ peptide has been used to study conformational changes in response to stimuli such as temperature and salt. The ccβ peptide adopts a three-stranded alpha-helical coiled-coil structure at low temperature and changes to an amyloid conformation with increasing temperature. The ccβ peptide can be used as a model for prion diseases and in amyloid studies. | price> |
| R-C-3988 | DSPE-PEG350-L-valine | Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups. | price> |
| R-R-5668 | Liposomes for Loading Hydrophobic Drugs | Liposomes for Loading Hydrophobic Drugs (5.0mL). This pre-formed liposome product is created for post loading of hydrophobic small molecule compounds into liposomes. The process of drug incorporation is very straight-forward. Then simply add an aliquot of drug solution (prepared in a water-miscible solvent such as ethanol, DMSO and etc.) into the liposome suspension. The drug molecules can be incorporated into the lipid bilayers by the nature of hydrophobic interactions. The drug solubility therefore could be significantly enhanced. Liposomal drug concentration of 1-2 mg/mL could be achieved for most lipophilic drugs. PEGylation of the liposomes provides not only better formulation stability but also the potential of achieving prolonged in vivo blood circulation. The finished drug loaded formulations are suitable for either in vitro testing or in vivo studies. | price> |
| R-M-1548 | Beta-Amyloid (12-20),CAS :134649-29-9 | β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Amino acids 12-20 of the amyloid beta peptide, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease. | price> |
| R-R-5669 | HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm) | HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). HSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain HSPC/CHOL liposomes as placebo control. | price> |
| R-M-1549 | Biotin-β Amyloid (1-42) Human,Cas:102577-21-9 | Amino acids 1-42 of amyloid beta protein, a key subunit of extracellular plaques found in the brains of patients with Alzheimer’s disease. Contains covalently attached N-Terminal Biotin tag for con-venient detection and purification. | price> |
| R-C-3990 | DSPE-polyethylene glycol550-L-valine | Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups. | price> |
| R-R-5670 | DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm) | DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). DSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain DSPC liposomes as placebo control (F10203). | price> |
| R-M-1551 | Pyroglutamyl β-Amyloid (4-14) Biotin | Pyroglutamyl β-Amyloid (4-14) Biotin is derived from Amyloid-β, which has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer’s disease (AD) and Down’s syndrome (DS). | price> |
| R-C-3991 | valine-L-PEG750-DSPE | Valine is one of the 20 amino acids that make up proteins.Its chemical name is 2-amino-3-methylbutyric acid.It works with two other high concentration amino acids(isoleucine and leucine)to promote normal body growth,repair tissues, regulate blood glucose and provide required energy.DSPE-PEG is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups. | price> |
| R-R-5671 | HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm) | HSPC/CHOL/mPEG-DSPE liposomes with ammonium gradient is the formulator choice in pharmaceutical/biotech industry for both formulation feasibility studies and liposomal product development, because HSPC is essentially equivalent to DSPC (HSPC contains about 85 % DSPC 15% DPPC). The main advantages for using HSPC are its lower cost and availability of GMP quality raw materials. | price> |
| R-M-1552 | RNase A (77-82) Amyloidogenic peptide | RNase A (77-82) is a site-specific endoribonuclease that cleaves amyloidogenic-peptide-associated-RNA and is used for the isolation of RNA-free DNA. Amyloidogenic peptide is an amyloid fibril which forms hexapeptides. | price> |
| R-C-3992 | DSPE-PEG350-VCAM1 | Vascular cell adhesion protein 1(VCAM1)is also known as CD106,INCAM-100 and L1CAM,is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily.VCAM1/CD106 contains 7 Ig-like C2-type(immunoglobulin-like) domains.1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.Suitable for the development of long circulating liposomes. | price> |
| R-R-5672 | DSPC/CHOL/mPEG-DSPE (50:45:5 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm) | This product is prepared to the finest quality and shipped to you ready for drug loading. DSPC/CHOL/mPEG-DSPE liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C) | price> |
| R-M-1553 | SEN 304 | SEN304 is a powerful inhibitor of Aβ aggregation and toxicity and therefore may be therapeutic for AD.SEN 304 can bind directly to Aβ(1-42), delay β-sheet formation and promote aggregation of toxic oligomers into a nontoxic form. | price> |
| R-C-3993 | DSPE-polyethylene glycol550-VCAM1 | Vascular cell adhesion protein 1(VCAM1)is also known as CD106,INCAM-100 and L1CAM,is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily.VCAM1/CD106 contains 7 Ig-like C2-type(immunoglobulin-like) domains.1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.Suitable for the development of long circulating liposomes. | price> |
| R-R-5673 | 1-(2-Deoxyribosyl)-2-pyrimidinone CAS:22003-30-1 | 1-(2-Deoxyribosyl)-2-pyrimidinone/1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone/CAS:22003-30-1 is a type of nucleoside, which is a molecule that plays a crucial role in various biological roles in life. Nucleosides are formed by a purine or pyrimidine base bonded to the anomeric carbon of ribo or 2-deoxyribose moiety . | price> |
| R-M-1554 | Tau (195-209) Heavy | Amino acids 195-209 of tubulin-associated unit (tau). This region represents a tau tryptic peptide and is part of the core of the tau protein. Tau is a phosphoprotein involved in microtubule (MT) assembly and stability as well as brain development. Tau is phosphorylated at multiple sites by several protein kinases, including cyclic-AMP-dependent protein kinases and casein kinase type-1. Tau phosphorylation causes tau to change shape, negatively regulating its ability to stimulate MT assembly. Tau is also glycosylated, and O-glycosylation may have a role in its subcellular localisation and degradation. | price> |

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