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Catalog | name | Description | price |
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R-R-0191 | CY3-gambogic acid | CY3 gambogic acid refers to the conjugate of fluorescent dye CY3 and natural compound gambogic acid. CY3 gambogic acid can be used for various research applications, especially in research related to its anticancer properties. By labeling gambogic acid with CY3, its localization, distribution, and interaction with cellular components can be visualized and monitored in real-time. This enables researchers to gain a deeper understanding of the mechanism of action, cellular uptake, and intracellular targeting of gambogic acid, which can help develop potential cancer therapies. | price> |
R-Mcs-191 | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiO-DBCO | The DOTAP:DOPC:Chol:DSPE-DBCO (5:64:30:1 molar ratio) fluoroliposomes containing DiO represent a versatile platform for various biomedical applications, including drug delivery and advanced imaging techniques. The combination of functional lipids and the fluorescent dye allows researchers to harness the benefits of liposomes for effective cellular targeting and tracking. | price> |
R-XASYS-00192 | Epiberberine chloride,cas:889665-86-5 | Epiberberine chloride is an alkaloid obtained from Coptis chinensis. It is an effective AChE and BChE inhibitor, and a non competitive BACE1 inhibitor with IC50 values of 1.07, 6.03, and 8.55, respectively μM.Epiberberine chloride has an antioxidant effect and can clear ONOO - (IC50, 16.83 μM) It can be used in the research of Alzheimers disease and diabetes. | price> |
R-R-0192 | Cupper(II) tetramethoxyphenylporphyrin CAS. 24249-30-7 | Cupper(II) tetramethoxyphenylporphyrin/5,10,15,20-Tetrakis(3-methoxyphenyl)porphyrinatonickel/ CAS. 24249-30-7 is a complex compound consisting of a copper atom coordinated with a tetramethoxyphenylporphyrin ligand. In Cu(II) tetramethoxyphenylporphyrin, the central copper atom is coordinated with the four nitrogen atoms of the porphyrin ring, forming a square planar geometry. The four methoxyphenyl groups are attached to the pyrrole units of the porphyrin ring, providing additional stability to the complex. This compound is commonly used in chemical research and catalysis due to its unique coordination properties and ability to interact with other molecules. | price> |
R-Mcs-192 | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome DiR-DBCO | The DOTAP:DOPC:Chol:DSPE-DBCO (5:64:30:1 molar ratio) fluoroliposomes loaded with DiR represent an innovative platform for a wide range of biomedical applications. Their design allows for effective drug delivery, highly sensitive imaging capabilities, and the potential for bioorthogonal targeting, making them an invaluable tool in modern research and therapeutic strategies. | price> |
R-XASYS-00193 | N-tert-Butyl-α-phenylnitrone,cas:3376-24-7 | N-tert-Butyl- α- Phenylnitrone is a nitrone-based free radical scavenger that can form nitric oxide spin adducts. N-tert-Butyl- α- Phenylnitrone inhibits the catalytic activity of COX2. N-tert-Butyl- α- Phenylnitrone has effective ROS clearance, anti-inflammatory, neuroprotective, anti-aging and anti diabetes effects, and can penetrate the blood brain barrier. | price> |
R-R-0193 | BSA-glucocorticoid | BSA-glucocorticoid/Bovine serum albumin-glucocorticoid refers to a conjugate of glucocorticoid hormone (such as cortisol or dexamethasone) covalently linked to bovine serum albumin (BSA).BSA-glucocorticoid conjugates can provide important insights into the pharmacokinetics and pharmacodynamics of glucocorticoids, allowing researchers to better understand their interactions with cells and tissues. Additionally, these conjugates can be utilized in the development of new drug delivery systems and targeted therapies. | price> |
R-Mcs-193 | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome Dansyl lipid (headgroup)-DBCO | DOTAP:DOPC:Chol:DSPE-DBCO(5:64:30:1molar ratio)-based Fluoroliposome Dansyl lipid (headgroup)-DBCO for effective drug delivery, highly sensitive imaging capabilities, and the potential for bioorthogonal targeting, making them an invaluable tool in modern research and therapeutic strategies. | price> |
R-XASYS-00194 | CL097,cas:1026249-18-2 | CL097 is an effective TLR7 and TLR8 agonist that can induce proinflammatory cytokines in macrophages. CL097 induces NADPH oxidase activation, leading to an increase in fMLF stimulated ROS production. | price> |
R-R-0194 | TPP-paclitaxel | TPP-paclitaxel refers to the conjugate of paclitaxel, a commonly used chemotherapy drug, with TPP (triphenylphosphonium) as a targeting moiety.The selective accumulation of TPP-paclitaxel in mitochondria allows for increased drug concentration at the site of action, enhancing its effectiveness and reducing systemic toxicity. This targeted delivery approach has shown promise in preclinical studies for improving the anti-cancer activity of paclitaxel. | price> |
R-Mcs-194 | DOTAP:DOPC:Chol:DSPE-N-DBCO-based Fluoroliposome NBD lipid (fatty acid tail)-DBCO | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome NBD lipid (fatty acid tail)-DBCO is a DOTAP-based Fluoroliposome-DBCO for Tracking and Detection. Drug delivery systems—where DOTAP enhances cellular uptake of therapeutics.Imaging studies—using the fluorescent properties of NBD to visualize liposome distribution in biological systems.Targeting studies—where the DSPE-N-DBCO allows conjugation of targeting ligands or other molecules via bioorthogonal reactions. | price> |
R-XASYS-00195 | 11-oxo-mogroside V,cas:126105-11-1 | 11-oxo-mogroside V(C60H100O29,1285.42) is a natural sweetener with strong antioxidant activity. 11-oxo-mogroside V has a significant inhibitory effect on active oxygen species, acting on O2 -, H2O2, and * OH, with an EC50 of 4.79, 16.52, and 146.17, respectively μ g/mL | price> |
R-R-0195 | 2-Iminothiolane hydrochloride CAS 4781-83-3 | 2-Iminothiolane hydrochloride (2IT) is a widely employed organosulfur compound in scientific research. Its primary application lies in synthesizing other compounds and conducting in vivo and in vitro studies, exploring biochemical and physiological impacts. Despite its potential benefits and drawbacks in laboratory experiments, 2IT continues to be of interest for various scientific pursuits.2IT finds utility in both in vivo studies conducted on animals and in vitro studies using tissue cultures or cell cultures. These studies delve into various scientific aspects, such as exploring biochemical and physiological effects. | price> |
R-Mcs-195 | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome NBD lipid (headgroup)-DBCO | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based FluoroliposomeNBD lipid (headgroup)-DBCO is a DOTAP-based Fluoroliposome-DBCO for Tracking and Detection. Drug Delivery: Leverage the cationic nature of DOTAP for delivering nucleic acids or small drugs.Imaging: Use the NBD fluorescence for tracking liposome behavior in vitro or in vivo.Targeting: Conjugate targeting moieties to the DSPE-N-DBCO to direct liposomes to specific cells or tissues. | price> |
R-XASYS-00196 | Simvastatin acid ammonium,cas:139893-43-9 | Simvastatin acid (Tenivastatin) ammonium is an effective inhibitor of HMG-CoA reductase (HMGCR). Simvastatin acid ammonium reduces the production of reactive oxygen species (ROS) mediated by indophenol sulfate. Simvastatin acid ammonium can also regulate OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with OATP3A1 gene. | price> |
R-R-0196 | TAMRA oleic acid | TAMRA oleic acid refers to the conjugation of the fluorescent dye TAMRA (Tetramethylrhodamine) with oleic acid, a common unsaturated fatty acid. TAMRA-oleic acid conjugates find applications in various research areas, including lipid metabolism, membrane dynamics, and cellular trafficking. They can be used in fluorescence microscopy, flow cytometry, and other imaging techniques to study lipid dynamics, lipid-protein interactions, and lipid-related diseases. | price> |
R-Mcs-196 | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome Pyrene lipid (headgroup)-DBCO | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based Fluoroliposome Pyrene lipid (headgroup)-DBCO is a DOTAP-based Fluoroliposome-DBCO for Tracking and Detection.Utilizing the cationic nature of DOTAP, the formulation can deliver drugs more effectively by enhancing cellular uptake. Pyrene fluorescence can be used to study membrane dynamics, interaction with other molecules, and the behavior of the liposomes within biological systems.Use the DBCO moiety for efficient bioconjugation, linking specific targeting agents to the liposome. | price> |
R-XASYS-00197 | Bigelovin,cas:3668-14-2 | Bigelovin(C17H20O5,304.34) is a sesquiterpene lactone that can be isolated from Sunflower and is a selective retinoin X receptorα(retinoid X receptorα) An agonist. Bigelovin can exert its anti-tumor activity by inducing apoptosis and autophagy. Bigelovin regulates the mTOR signal pathway by inhibiting ROS generation. | price> |
R-R-0197 | Hydroxy-PEG2-CH2COOH cas 51951-04-3 | Hydroxy-PEG2-CH2CO2H, sodium salt linker contains a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond. The PEG spacer increases the aqueous solubility of the resulting compound. The hydroxyl group can be further functionalized for bioconjugation purposes. | price> |
R-Mcs-197 | DOTAP:DOPC:Chol:DSPE-N-DBCO-based FluoroliposomeRhodamine lipid (headgroup)-DBCO | DOTAP:DOPC:Chol:DSPE-N-DBCO(5:64:30:1molar ratio)-based FluoroliposomeRhodamine lipid (headgroup)-DBCO is a DOTAP-based Fluoroliposome-DBCO for Tracking and Detection.The cationic nature of DOTAP may enhance the uptake of drugs or genes into cells.Rhodamine provides a fluorescent marker, facilitating studies on liposome dynamics and interaction with target cells or tissues.The DBCO moiety can be used for site-specific bioconjugation, enabling targeted drug delivery systems. | price> |