Product fluorescent-dyes-fluorescent-enzyme-substrates

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Catalog	name	Description	price
R-C-3646	3-Cyanoumbelliferone	Light red powder. Soluble in alcohols or DMF. Phenolic dyes with high pKas - such as 7-hydroxycoumarin (often called umbelliferone) and the more common 7-hydroxy-4-methylcoumarin - are not fully deprotonated and therefore not fully fluorescent unless the pH of the reaction mixture is raised to above pH ~10.	price>
R-C-3647	DiFMUP	DiFMUP is a fluorogenic substrate for phosphatases.Upon enzymatic cleavage by phosphatases, 4-methylumbelliferone(4-?U)is released and its fluorescence can be used to quantify phosphatase activity. DiFMUP has been used to detect alkaline phosphatase in isolated rat tibia bone tissue.	price>
R-C-3648	4-Methylumbelliferyl Oleate	4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4.	price>
R-C-3651	4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside	4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate for palmitoyl-protein thioesterase(PPT),a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins.It is cleaved by PPT to produce fluorescent moiety 4-MU.	price>
R-C-3652	4-Methylumbelliferyl Palmitate	4-Methylumbelliferyl palmitate(4-MUP)is a fluorogenic substrate for lysosomal acid lypase (LAL).4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU.	price>
R-C-3653	4-Methylumbelliferyl 2-sulfamino-2-deoxy-a-D-Glucopyranoside sodium salt	4-Methylumbelliferyl 2-sulfamino-2-deoxy-alpha-D-Glucopyranoside(4-MU-alpha-GlcNS)is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-alpha-GlcNS to yield 4-MU-alpha-GlcNH2, which is then cleaved by alpha-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm.	price>

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