Altiratinib CAS:1345847-93-9

Altiratinib,also known as DCC-270,DP-5164,is an oral,selective and highly potent inhibitor of MET,TIE2,VEGFR2 and TRK kinases with potential anticancer activity.DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling,cell growth and migration as compared with a HGF antagonist in vitro. Importantly,DCC-2701 is anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF.

msds---Altiratinib