AMG-548 dihydrochloride CAS No.2518299-32-4
AMG-548 dihydrochloride CAS No.2518299-32-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-4486 | 5mg | 380.00 | + Add to cart |
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| R-R-4486 | 10mg | 650.00 | + Add to cart |
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Product description
AMG-548 dihydrochloride/CAS No.2518299-32-4, an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ. AMG-548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM). AMG-548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε.
| Appearance | N/A |
|---|---|
| Molecular Weight | 534.48 |
| Purity | >90% |
| CAS | 2518299-32-4 |
| Formula | C29H29Cl2N5O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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