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Email:sales@ruixibiotech.com
Tel.:02988811435
Cu-ATSP,cas:68341-12-8
(SP-4-2)-[[2, 2-(1,2-dimethyl-1,2-ethanediylidene)bis[N-phenylhydrazinecarbothioamidato-κN2,κS]](2-)]-copper
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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| R-XASYS-00050 | 10mg | 327.00 | + Add to cart |
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| R-XASYS-00050 | 25mg | 764.00 | + Add to cart |
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Product description
Cu-ATSP(C18H18CuN6S2,446.1) is a copper-containing bis(thiosemicarbazone) complex with ferroptosis inhibitory activity.It traps peroxyl radicals in a cell-free assay when used at a concentration of 6 µM. Cu-ATSP inhibits ferroptosis induced by (1S,3R)-RSL3 in Pfa1 mouse embryonic fibroblasts (MEFs) and HT22 mouse hippocampal cells (EC50s = 8.5 and 16 nM, respectively). It increases intracellular copper levels but, unlike the bis(thiosemicarbazone) complexes Cu-CQ2 and CuNC2, does not reduce amyloid-β (1-40) (Aβ40) levels in CHO cells overexpressing amyloid precursor protein (APP).
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| Purity | >90% |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 3 weeks |
| Stability | 1 year |
Document
msds of Cu-ATSP Related Product
RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com
