D3 style ASO

D3 style ASOis a dual functional chimeric ASO with a clear sequence, directly covalently coupling the 5 G-quadruplex aptamer domain and the 3 antisense domain through a continuous poly-T linker. It is a typical non fragmented intelligent nucleic acid drug model probe that integrates high affinity targeting+long-acting gene silencing.

msds of D3 style ASO