DOPS:DOPC:Chol:DOPE-N-DBCO(20:49:30:1molar ratio)-based Fluoroliposome Cyanine 5 lipid-DBCO

DOPS:DOPC:Chol:DOPE-N-DBCO(20:49:30:1molar ratio)-based Fluoroliposome Cyanine 5 lipid-DBCO can potentially be used in the field of theranostics, which combines therapy and diagnostics. By attaching therapeutic agents for treatment and fluorescent tags for imaging, one could monitor therapeutic responses in real time.The DBCO group allows for the covalent attachment of azide-functionalized therapeutic agents directly inside or on the surface of the liposome. This enables precise targeting strategies, potentially enhancing efficacy while reducing systemic toxicity.
The Cyanine 5 lipid provides a means for non-invasive imaging, enabling visualization of liposome distribution and cellular uptake through fluorescence imaging techniques.This is particularly valuable in applications such as in vivo tumor targeting studies, tracking the biodistribution of therapeutics, or studying cellular dynamics.The strong fluorescence from the Cyanine 5 allows for real-time monitoring of liposome internalization, localization, and migration in live cells using fluorescence microscopy techniques.

msds of dops-dopc-chol-dope-n-dbco-20-49-30-1-molar-ratio-based-fluoroliposome-cyanine-5-lipid-dbco