DOTAP:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-based Fluoroliposome DiD-Azide

DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome DiD-Azide is a DOTAP-based Fluoroliposome-Azide for Tracking and Detection.
DOTAP:DOPC:Chol:1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-azidohexanoyl) (ammonium salt){5:64:30:1molar ratio}-based Fluoroliposome DiD-Azide can be utilized for delivering nucleic acids (DNA/RNA) or small molecule drugs to cells. The cationic nature of DOTAP can enhance the encapsulation and cellular uptake of negatively charged therapeutics.
The inclusion of the DiD dye allows researchers to visualize the liposomes in vitro or in vivo, facilitating studies on pharmacokinetics and biodistribution.
The azide group can serve as a reactive handle for bioorthogonal labeling or conjugation to target moieties (e.g., antibodies or peptides) to improve specificity in targeting disease sites.
Such formulations can also be beneficial for vaccine delivery, helping to present antigens in a way that enhances immune responses.

msds of dotap-dopc-chol-dppe-n-6-azidohexanoyl-ammonium-salt-based-fluoroliposome-did-azide