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L748337 CAS No.244192-94-7
L748337 CAS No.244192-94-7
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-3599 | 10mg | 280.00 | + Add to cart |
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| R-R-3599 | 25mg | 560.00 | + Add to cart |
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Product description
L748337/CAS No.244192-94-7 is a potent β3-adrenergic receptor antagonist and displays selectivity over β1 and β2 receptors. The Ki values of L748337 for β3-, β2- and β1-adrenoceptors are 4.0 nM, 204 nM and 390 nM, respectively. L748337 couples predominantly to Gi to activate MAPK signaling and increases phosphorylation of Erk1/2 with pEC50 value of 11.6. L748337 can be used for the research of cancer, nonalcoholic fatty liver disease (NAFLD), and cardiovascular related diseases.
| Appearance | N/A |
|---|---|
| Molecular Weight | 497.61 |
| Purity | >90% |
| CAS | 244192-94-7 |
| Formula | C26H31N3O5S |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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