PEG-(hollow MnO2 modified with Na2CO3)@lactate oxidase

PEG-(hollow MnO2 modified with Na2CO3)@lactate oxidase/PEG modification(hollow MnO2 modified with Na2CO3)Encapsulated lactate oxidase/PEG modification(hollow manganese dioxide modified with sodium carbonate)Encapsulated lactate oxidase are an intelligent biological nanoplatform that integrates nanocarriers, enzyme catalysis, and microenvironment regulation. It is designed specifically for tumor metabolism intervention, hypoxia relief, and immune microenvironment remodeling. The system is based on hollow MnO ₂ with a particle size of 100-150nm. After alkaline modification on the surface of Na ₂ CO3, a polyethylene glycol (PEG) layer is introduced, and lactate oxidase (LOx) is covalently or physically coupled to achieve targeted clearance of high concentrations of lactate and in-situ generation of reactive oxygen species (ROS) in the tumor microenvironment.

msds of PEG-(hollow MnO2 modified with Na2CO3)@lactate oxidase