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Home > products > block-copolymer > plga-peg > plga-hydrazone-peg-sh

PLGA-Hydrazone(hyd)-PEG-SH

Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-thiol

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-CG-035 100mg 600.00
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  •     PLGA Molecular Weight    
  •   
  •     PEG Molecular Weight    
  •   
  •     LA:GA    
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Product description

Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-SH，PLGA-SS-PEG-thiol from ruixi.Hydrazone bond has pH response effect. DSPE was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.


Appearance White powder or viscous liquid depends on molecular weight
PEG Molecular weight 750/1000/2000/3400/5000/10000
MW of PLGA As your request
PDI by GPC <1.5
Solubility organic solvents
Storage -20℃, protected from light and moisture
Transportationc 4-25℃ temperature for up to 3 weeks
Stability 1 year
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MSDS of PLGA-Hydrazone(hyd)-PEG-SH
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