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R-M2-9694 Biotin-6-aminocaproyl hydrazide,cas:109276-34-8 Biotin-6-aminocaproyl hydrazide can be used to biotinylate proteins, peptides, and other biomolecules. This is useful for labeling molecules for various assays or for purification purposes. Due to the strong binding affinity of biotin to streptavidin or avidin, the biotinylated compounds can be easily purified from a mixture, detected in assays, or immobilized on surfaces for different applications. This compound can be utilized in assays like Western blotting or ELISA to enhance detection sensitivity of target proteins by labeling them with biotin for enzyme-linked detection methods. Biotin conjugates can be used for studying protein localization, trafficking, and interactions in live cells. This is particularly useful in imaging studies using fluorescence microscopy. The biotinylated compounds can be used in targeted drug delivery systems because many cells (especially those in certain tissues) express receptors specific to biotin, allowing for facilitated uptake of the drug. price>
R-M1-8060 Pomalidomide-PEG4-COOH Pomalidomide,the third-generation immunomodulatory agent,acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. price>
R-C-5677 PLGA20K-PEG2K-transferrin Transferrin is a protein present in the body that binds to transferrin receptors, which are overexpressed on the surface of certain cells, including cancer cells. By conjugating transferrin to PLGA-PEG, the bioconjugate can specifically target cells that have high levels of transferrin receptors.The PLGA-PEG-transferrin combining these components, the bioconjugate can improve the specificity and efficacy of drug delivery, particularly for diseases where transferrin receptor expression is upregulated. price>
R-M2-9695 SAM(S-adenosylmethionine)-Biotin Biotin-conjugated SAM can be used to study methyltransferases and their substrates, allowing for more straightforward detection and analysis of enzymatic activity. Researchers can biotinylate proteins or other biomolecules with SAM attached, facilitating the study of methylation patterns in proteins. The conjugate may be used in drug delivery systems targeting methylation-related disease pathways—leveraging the specificity of biotin to guide drugs to specific tissues. It can be employed to trace and study methylation pathways in cells, helping elucidate the roles of SAM in various physiological and pathological contexts. price>
R-M2-9696 SAH(S-adenosyl homocysteine)-Biotin Biotin-conjugated SAH can be used to study the inhibition of methyltransferase enzymes since its presence can help elucidate the kinetics and regulation of SAM-dependent reactions in vitro or in vivo. Researchers can track changes in methylation patterns in cells by introducing biotin-conjugated SAH into the cellular environment, allowing for assessments of methylation status and related metabolic effects. price>
R-M1-8061 DOTA-PEG-DBCO DBCO is used in Click Chemistry reactions due to its high strain energy. The DOTA complex has wide medical applications as contrast agents and cancer treatments. DBCO group adds a powerful handle to conjugate DOTA complex to the biomolecule of interest. The PEG spaer provides additional solubility of the newly formed complex in aqueous media. price>
R-C-5678 DSPE-PEG2000-KLVFF-K-FITC DSPE-PEG-KLVFF-K-FITC,1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) is a phospholipid derivative commonly used in liposomal formulations.It provides stability and integrity to lipid-based systems.Polyethylene glycol (PEG) with a molecular weight of 2000 is a hydrophilic polymer used in bioconjugation to enhance solubility,stability,and extend circulation time.KLVFF is a peptide sequence derived from the amyloid-beta protein.Fluorescein isothiocyanate (FITC) is a fluorescent dye commonly used in bioimaging and detection applications. It can be conjugated to biomolecules to visualize and track them. price>
R-M1-8062 CY5-Hyaluronate360K CY5-Hyaluronate(Cyanine5-HA),Excitation 640nm, Emission 660nm. price>
R-C-5679 DSPE-TK-PEG2K-HA50K DSPE-TK-PEG-HA is a phospholipid ester targeted drug polyethylene glycol 2000 hyaluronic acid copolymer widely used in nano drug delivery systems.The pharmaceutical component TK has activity, PEG2000 enhances the stability and biocompatibility of nanoparticles,and hyaluronic acid (HA)provides specific recognition.Through this copolymer, drugs can be more effectively transported. price>
R-M2-9697 DOTA-Biotin DOTA-Biotin can be used to tag proteins, antibodies, or other biomolecules for detection and separation. The biotin portion allows for specific binding to streptavidin-coated surfaces or beads, facilitating purification and study. DOTA-Biotin can be conjugated with cytotoxic agents or radiopharmaceuticals for targeted therapy. The biotin component allows these therapies to selectively bind to biotin receptors in overexpressing cells. In diagnostic assays, DOTA-Biotin can serve as a tracer in biotin-based enzyme-linked immunosorbent assays (ELISAs) and similar methodologies, allowing for sensitive detection of specific biomolecules. price>
R-M1-8063 Protein A-Biotin Biotin-Protein A, which is produced by covalently linking biotin to protein A, can be used in immunodetections, such as immunoblotting (western or dot blot), ELISA, and immunohistochemistry. price>
R-C-5680 Pluronic F127 Pluronic F127 (F127) composition polyoxyethylene-polyoxypropylene-polyoxyethylene (PEO-PPO-PEO), where PEO is hydrophilic and PPO is lipophilic. When this copolymer is heated to physiological temperature (ie, ~37 °C), the hydrophobic PPO block dehydrates and crosslinks with the hydrophilic PEO block to form spherical microgels. price>
R-M2-9698 FITC-protein(hydrolyzed soybean+hydrolyzed rice+hydrolyzed wheat) FITC-labeled proteins are commonly used for visualizing the distribution of proteins in cells or tissues through fluorescence microscopy. They can help elucidate cellular localization and interactions. FITC-proteins can be utilized to analyze cell populations based on specific protein expression using flow cytometry. This application is helpful in immunology and cancer research. FITC-labeled proteins can serve as detection antibodies in ELISA assays, enabling sensitive quantification of target antigens in biological samples. Used in studying protein-protein interactions through fluorescence resonance energy transfer (FRET), allowing researchers to monitor and quantify molecular interactions in real-time. price>
R-M1-8064 Protein A-Thiol Protein A-Thiol, which is produced by covalently linking Thiol to protein A, can be used in immunodetections, such as immunoblotting (western or dot blot), ELISA, and immunohistochemistry. price>
R-C-5681 Pluronic F127-NH2 Pluronic F127 (F127) composition polyoxyethylene-polyoxypropylene-polyoxyethylene (PEO-PPO-PEO), where PEO is hydrophilic and PPO is lipophilic. When this copolymer is heated to physiological temperature (ie, ~37 °C), the hydrophobic PPO block dehydrates and crosslinks with the hydrophilic PEO block to form spherical microgels. price>
R-M2-9699 Biotin-caffeic acid Investigating the effects of biotin-caffeic acid in various biological assays can help uncover potential therapeutic applications, particularly in antioxidant or inflammatory conditions. Biotin-caffeic acid represents a promising compound that combines the advantageous properties of biotin and caffeic acid. Its potential uses span dietary supplements, cosmetics, and pharmaceuticals, supporting health claims related to skin, hair, nails, and metabolic function. Further research into its efficacy, safety, and applications could yield valuable options for enhancing health and wellness. All products provided by the company are for scientific research purposes only and cannot be used on the human body. price>
R-M1-8065 4 arm-PEG-RGD 4 arm-PEG-RGD is a multi-arm polyethylene glycol with RGD at each terminal of the four arms, it have multiple reactive groups that can be used to modify proteins, peptides and other materials via their functional groups price>
R-C-5682 Fe3O4 nanorods-PEG1000-FA Diameter:10nm, length:100nm Fe3O4 nanorods as the core material, have magnetic properties and can be manipulated by external magnetic fields.Therefore,they have potential application value in targeted drug delivery and magnetic resonance imaging(NMR)applications.The modification of polyethylene glycol makes nanomaterials more stable and improves their biocompatibility.FA (folic acid) is usually attached to the surface of nanomaterials to achieve selective targeting of cancer cells. price>
R-M2-9700 RRRRRRRR-mPEG2K RRRRRRRR-mPEG2K/mPEG2K-RRRRRRRR is a useful surface modifier or delivery vector in nanomedicine, drug delivery systems, and bioconjugation strategies. It is often used to functionalize liposomes or nanoparticles for enhanced cellular uptake,deliver cargo molecules like RNA,proteins or small drugs,maintain a hydrophilic, biocompatible shell to reduce clearance and improve biodistribution. price>
R-M1-8066 BSA-MnO2 NPs, 5nm (Aqueous solution) MnO2 nanoparticles coated bovine serum albumin (BSA) displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.Using bovine serum protein as biological template and reducing agent. price>