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R-M2-9813 E2s protein-(Mal-PEG1-Val-Cit-PABC-OH)-artesunate E2s protein-(Mal-PEG1-Val-Cit-PABC-OH)-artesunate is a protein–drug conjugate (PDC) or bioconjugate, constructed for targeted or controlled drug delivery. Applications: Targeted protein-drug conjugate therapy for cancer or other diseases with cathepsin B overexpression. Controlled-release drug delivery with enzyme-triggered activation. Potential theranostic conjugate if E2s is also functionalized for imaging or targeting price>
R-C-7376 PAMAM G4-mPEG PAMAM G4-mPEG,PAMAM-G4-PEG2K,(mPEG-PAMAM-G4)is a composite carrier formed by covalent coupling of a fourth generation polyamide amine dendritic polymer (PAMAM)with methoxypolyethylene glycol(mPEG)This structure combines the high loading capacity of PAMAM with the long cycling and low toxicity advantages of mPEG, making it one of the core delivery platforms in current targeted therapy systems PAMAM G4 has approximately 64 surface amino groups and can efficiently bind to negatively charged molecules such as nucleic acids(such as siRNA,mRNA,DNA)and anticancer drugs(such as doxorubicin,camptothecin)through electrostatic interactions or covalent bonds.This product is only for scientific research and cannot be used on the human body. price>
R-M1-8180 PS microsphere-biotin 500 nm PS microsphere-biotin 500 nm,PS microsphere modified biotin 500 nm from kamulin. price>
R-C-5797 DSPE-PEG2000-OCH3 DSPE-PEG-OCH3,DSPE is a phospholipid commonly used in the formulation of lipid-based drug delivery systems such as liposomes and lipid nanoparticles.PEGylation can improve the stability and circulation time of the nanoparticles by reducing interactions with proteins and immune recognition.This can lead to improved drug delivery efficiency and reduced clearance rates.The methoxy group (-OCH3) at the end of the PEG chain in DSPE-PEG-OCH3 is often used as a spacer between the nanoparticle surface and any targeting ligands or functional moieties that may be attached. The methoxy group can provide flexibility and prevent steric hindrance, allowing for effective conjugation of targeting ligands or other molecules. price>
R-M2-9814 Artesunate-E2s protein(148 amino acids) Artesunate-E2s protein(148 amino acids) is a protein-drug conjugate (PDC) composed.Ubiquitin-conjugating enzymes (E2s)/E2s Protein (148 amino acids) : refers to proteins in the E2 family.A medium-sized protein (~16–18 kDa, depending on sequence) that serves as a carrier or targeting moiety. Its function can range from tumor targeting to carrier-mediated delivery, depending on the intrinsic properties of protein. Applications: Targeted cancer therapy: Artesunate has demonstrated anticancer potential via oxidative stress pathways. Protein-based drug delivery: Enhances solubility, stability, and pharmacokinetics of artesunate. Potential theranostic systems if E2s is further functionalized with imaging or targeting motifs. price>
R-C-7377 PLA5K-SS-PEI2K Poly(D,L-lactide)- SS-Polyvinylene imine is a redox responsive copolymer composed of biodegradable racemic polylactic acid(PDLLA)and cationic polymer polyethyleneimine(PEI)connected by disulfide bonds(-SS-).PDLLA provides good biocompatibility and degradability,while PEI achieves efficient nucleic acid compression and cell transfection ability with its high-density amino groups.The disulfide bond in the middle serves as an intelligent switch that exists stably outside the cell.After entering the cell,it breaks due to the high concentration of glutathione(GSH)environment inside the cell,triggering the rapid release of nucleic acids(such as siRNA and pDNA),significantly improving transfection efficiency and reducing toxicity.This product is only for scientific research and cannot be used on the human body. price>
R-M1-8181 TZ-PEG4-NH2,HCl TZ-PEG4-NH2,HCl,Tetrazine-polyethylene glycol4-amine ,HCl is a heterobifunctional peg reagent. price>
R-C-5798 PPS N=120 Polyphenylene sulfide is a high-performance engineering thermoplastic that exhibits excellent thermal stability, chemical resistance,and mechanical properties.The number-average molecular weight, N=120, suggests that the polymer has an average chain length of 120 repeat units. The molecular weight of a polymer can affect its mechanical properties, processability, and performance in different applications. price>
R-M2xa-9815 IR820-COOH IR820-COOH is a near-infrared (NIR) fluorescent dye derivative in which IR820 (a heptamethine cyanine dye similar to indocyanine green, ICG) is chemically modified to introduce a carboxyl (-COOH) group for conjugation or functionalization. Applications: Photothermal therapy (PTT): Converts NIR light to heat for tumor ablation. Fluorescence imaging: For in vivo tumor visualization and biodistribution studies. Photoacoustic imaging: Dual-mode imaging when integrated into nanocarriers. Drug delivery systems: As a functional probe to track or activate nanocarriers. price>
R-C-7378 DSPE-TK-PEG-CAQK CAQK-PEG-TK-DSPE,DSPE-TK-PEG-CAQK is a multifunctional intelligent responsive lipid polymer copolymer that has shown great potential in tumor targeted therapy,nerve injury repair,and nucleic acid drug delivery.This material achieves precise and efficient drug delivery through three major mechanisms:ROS responsive release,long cycling characteristics, and tissue-specific targeting.This product is only for scientific research and cannot be used on the human body. price>
R-M1-8182 Cholesterol-Azide Cholesterol is an important lipid of mammalian cells and plays a fundamental role in many biological processes. Its concentration in the various cellular membranes differs and is tightly regulated. Here, we present a novel Azide cholesterol analog suitable for tracing both cholesterol metabolism and localization. This probe can be detected by click chemistry employing various reporter azides. price>
R-C-5799 PCL30-R9(arginine)-NH2 PCL-R9(arginine)-NH2,PCL offers good solubility in organic solvents,processability,and controlled degradation properties,making it suitable for various applications.Arginine is a naturally occurring amino acid with properties that are beneficial for drug delivery and biological interactions.The inclusion of arginine in the copolymer structure can facilitate cell penetration,enhance cellular uptake, and potentially improve the delivery of drugs or therapeutic agents. price>
R-M2cq-9816 IR820-HA MW:40k IR820-HA MW:40k/IR820-HA40k/IR820-hyaluronic acid40000 is a hyaluronic acid (HA)-conjugated near-infrared (NIR) probe. Applications: Targeted photothermal therapy (PTT) for tumors or inflammatory tissues. NIR fluorescence and photoacoustic imaging of CD44-positive lesions. Theranostic nanocarrier component when further incorporated into nanoparticles or liposomes. price>
R-C-7379 DSPE-TK-PEG-SFHQFARATLAS DSPE-TK-PEG-HAP-1,DSPE hydrophobic tail enables self-assembly of liposomes or nanovesicles,PEG2000 chain provides hydration barrier and cycle extension, and the terminal TK bond responds to reactive oxygen species, achieving environment triggered drug release.SFHQFARATLAS(HAP-1 peptide)is a synovial fibroblast(FLS)targeted transduction peptide that can specifically recognize and penetrate FLS that proliferates excessively in RA lesions,with dual functions of targeting and cell penetration.This product is only for scientific research and cannot be used on the human body. price>
R-M1-8183 FmocNH-(CH2)3-PEG2000-(CH2)5-COOSu FmocNH-(CH2)3-PEG2000-(CH2)5-COOSu is a synthetic peptide compound that can be used as a targeted drug carrier for in vitro and in vivo animal studies. price>
R-C-5800 DSPE-PEG2K-PBP(CDAEWVDVS) DSPE-PEG-PBP,DSPE is a phospholipid commonly used in the formulation of lipid-based drug delivery systems,providing stability and structure to the nanoparticles.PEGylation involves attaching PEG chains to the molecule,offering improved stability, circulation time, and reduced immunogenicity.The peptide sequence PBP(CDAEWVDVS) is attached to the PEG chain. price>
R-M2xa-9817 IR820-NH2 IR820-NH2 is a near-infrared (NIR) fluorescent dye derived from the heptamethine cyanine dye IR820, functionalized with a primary amine (-NH₂) group. This modification enables further chemical coupling via amide, urea, or thiourea bond formation, making it a versatile building block for bioconjugation. Applications Conjugation to carboxyl-containing biomolecules (e.g., hyaluronic acid, peptides, proteins). Liposome and nanoparticle surface modification for NIR fluorescence and photothermal functions. Dual-function theranostic agents when combined with targeting ligands or therapeutic molecules. Fluorescent probes for imaging and biodistribution studies. price>
R-C-7380 DSPE-PEG-SFHQFARATLAS SFHQFARATLAS-PEG-DSPE,DSPE-PEG-HAP-1,DSPE-PEG-HAP-1 can be used as a modular tool to further couple mRNA, protein drugs,or immunomodulators,expanding to the development of intelligent treatment systems for autoimmune diseases,osteoarthritis, and other fields.The uniqueness of HAP-1 peptide lies in its combination of targeting and penetration properties,unlike ordinary ligands that can only bind to surface receptors.This product is only for scientific research and cannot be used on the human body. price>
R-M1-8184 NOTA-PEG-SH NOTA-PEG1k-SH,1,4,7-Triazacyclononane-1,4,7-triacetic acid-PEG1k-SH from kamulin.NOTA, is a triaza macrocyclic ligand that has shown to have potential to act as scintigraphic and PET (Positron Emission Tomog.) imaging agents. price>
R-C-5801 DSPE-PEG2K-VHPKQHR DSPE-PEG-VHPKQHR,By adding a cysteine group to the N-terminus of VHPKQHR peptide, a VCAM-1-binding peptide derived from phage display in vivo85,the linkage of CVHPKQHR to distearoyl phosphoethanolamine-poly(ethylene glycol) 2000-maleimide (DSPE-PEG2000-maleimide) was facilitated through thioether linkage,forming DSPE-PEG2000-VHPKQHR. price>