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Catalog | name | Description | price |
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R-XASYS-00411 | ML-211,cas:2205032-89-7 | ML-211(C25H30N4O2,418.541) is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM) | price> |
R-R-0411 | Cyclo(D-Phe-L-Pro) | Cyclo(D-Phe-L-Pro)/CAS:26488-24-4 is a cyclic dipeptide formed by the cyclization of the D-phenylalanine (D-Phe) and L-proline (L-Pro). Cyclic dipeptides have been of interest in pharmacology and medicinal chemistry due to their potential bioactivities and pharmaceutical applications. The specific properties and potential applications of Cyclo(D-Phe-L-Pro) would depend on its structure, and it might be relevant for research and potentially used in pharmaceutical and biomedical fields. | price> |
R-Mcs-411 | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine Fluorescent Lipid NBD lipid (headgroup) | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine (57:38:4:1molar ratio)Fluorescent Lipid NBD lipid (headgroup) is a PEGylated fluorescent liposome nanomaterials. End Uses: In vivo and in vitro imaging:Near-infrared fluorescence (Ex/Em≈644/665 nm) allows deep-tissue imaging with low background autofluorescence. Biodistribution and pharmacokinetic studies:Tracks liposome circulation, accumulation, and clearance in real time. Cellular uptake and trafficking analysis:Visualizes liposome-cell interactions and intracellular fate. Targeted delivery research:The amine-functionalized PEG enables ligand or antibody conjugation for targeted drug delivery systems. Theranostic platform development:Can be combined with therapeutic agents to create image-guided drug delivery systems. | price> |
R-PS2000-01 | PEG-SS-PCL-PEI-branched | PEG-SS-PCL-PEI-branched,polyethylene glycol-s-s-Poly(ε-caprolactone)-Polyethyleneimine-branched from ruixi.Ruixi is a biotechnology company. PEG-SS-PCL-PEI-branched is an amphiphilic block copolymer.PEG-SS-PCL-PEI-branched is a branched peg reagent with disulfide bond,Poly(ε-caprolactone)and polyethyleneimine. | price> |
R-XASYS-00412 | DHODH-IN-11,cas:1263303-95-2 | DHODH-IN-11(C15H11N3O2,265.27) is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | price> |
R-R-0412 | Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide | Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide/CAS 143120-27-8 from ruixi.This sulfur-bridged cyclic RGD peptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC?? of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC?? = 0.15 µM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases. | price> |
R-Mcs-412 | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine Fluorescent Lipid Pyrene lipid (headgroup) | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine (57:38:4:1molar ratio)Fluorescent Lipid Pyrene lipid (headgroup) is a PEGylated fluorescent liposome nanomaterials. End Uses: In vivo and in vitro imaging:Near-infrared fluorescence (Ex/Em≈644/665 nm) allows deep-tissue imaging with low background autofluorescence. Biodistribution and pharmacokinetic studies:Tracks liposome circulation, accumulation, and clearance in real time. Cellular uptake and trafficking analysis:Visualizes liposome-cell interactions and intracellular fate. Targeted delivery research:The amine-functionalized PEG enables ligand or antibody conjugation for targeted drug delivery systems. Theranostic platform development:Can be combined with therapeutic agents to create image-guided drug delivery systems. | price> |
R-P-0012 | MPEG2k-PPS-COOH | Methoxy polyethylene glycol-Polyphenylene sulfide-Carboxyl,MPEG2000-PPS-COOH from ruixi.Ruixi is a biotechnology company.MPEG2000-PPS-COOH is a heterofunctional polyethylene glycol derivative. One end of MPEG is connected with PPS and the other end is connected with COOH. We provide high quality and diverse polyethylene glycol derivatives. We can provide macromolecular PEG derivatives and small molecule derivatives, such as 300, 350, 400, 1000, 2000, 3400,etc.We can also customize some products through the information you provide. | price> |
R-XASYS-00413 | TBCA,cas:934358-00-6 | TBCA(C9H4Br4O2,463.7) is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 µM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 µM), driving caspase-dependent degradation of poly-ADP ribose polymerase while inhibiting CK2 activity. | price> |
R-R-0413 | Pasireotide | Pasireotide (SOM230) Cas.396091-73-9, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity. | price> |
R-Mcs-413 | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine Fluorescent Lipid Rhodamine lipid (headgroup) | HSPC:Chol:DSPE-PEG(2000):DSPE-PEG(2000)-Amine(57:38:4:1molar ratio)Fluorescent Lipid Rhodamine lipid (headgroup) is a PEGylated fluorescent liposome nanomaterials. End Uses: In vivo and in vitro imaging:Near-infrared fluorescence (Ex/Em≈644/665 nm) allows deep-tissue imaging with low background autofluorescence. Biodistribution and pharmacokinetic studies:Tracks liposome circulation, accumulation, and clearance in real time. Cellular uptake and trafficking analysis:Visualizes liposome-cell interactions and intracellular fate. Targeted delivery research:The amine-functionalized PEG enables ligand or antibody conjugation for targeted drug delivery systems. Theranostic platform development:Can be combined with therapeutic agents to create image-guided drug delivery systems. | price> |
R-PLE0021 | PEI10k-SS-PEG2000-COOH | Polyethylenimine-s-s-Polyethylene glycol-Carboxylic,PEI10000-SS-PEG2000-COOH from ruixi.Polyethyleneimine (PEI) is a widely studied non viral vector for gene delivery. Its main advantage is good transfection effect in vitro.Polyethyleneimine (PEI) is a widely studied non viral vector for gene delivery. Disulfide bond is an ideal biodegradable bond, which can be used to design gene delivery vector. | price> |
R-XASYS-00414 | Tripolin A,cas:1148118-92-6 | Tripolin A(C15H11NO3,253.3) is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5μM and 7μM, respectively) | price> |
R-R-0414 | Cyclo(L-Pro-L-Trp) | Brevianamide F/Cyclo(L-Pro-L-Trp)/CAS:38136-70-8, belongs to a class of naturally occurring 2,5-diketopiperazines. It is the simplest member and the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by the fungi A.fumigates and Aspergillus sp. It has been isolated from the bacterium Streptomyces sp. strain TN58 and shown to possess activity against two Gram-positive bacteria, S.aureus and Micrococcus luteus, and has also been isolated from Bacillus cereus associated with the entomopathogenic nematode, Rhabditis (Oscheius) sp. and shown to have antifungal activity against T. rubrum, C. neoformans and C. albicans, better than amphotericin B | price> |
R-QD-0061 | streptavidin-cdSe/zns-quantum-dots-610nm | Streptavidin-CdSe/ZnS quantum dots,Streptavidin modified CdSe/ZnS quantum dots from ruixi.Quantum dots (QDs) are semiconductor nanocrystals with excellent spectral characteristics and photochemical stability.Therefore,quantum dots as biological fluorescent probes will have broad application prospects in immunobiology and clinical laboratory studies. | price> |
R-XASYS-00415 | (E/Z)-GO289,cas:694522-87-7 | (E/Z)-GO289(C17H15BrN4O2S,419.3), which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity. | price> |
R-R-0415 | Cyclo(D-Leu-L-Pro) | Cyclo(D-Leu-L-Pro)CAS:36238-67-2 is a cyclic dipeptide formed by the cyclization of the D-isomer of leucine (D-Leu) and the L-isomer of proline (L-Pro). The cyclization process results in the formation of a ring structure that can impart unique properties to the dipeptide. | price> |
RZ- 008 | Water-soluble Ag2S quantum dots | Ag2S quantum dots have high fluorescence efficiency and biocompatibility,which will have a good application prospect in vivo imaging,detection,diagnosis and so on.Ag2S QDs can also be used as an excellent near-infrared optical imaging probe,which provides an opportunity for nano diagnosis and in vivo imaging research. | price> |
R-XASYS-00416 | (E/Z)-GSK-3βinhibitor 1,cas:3367-88-2 | GSK-3βinhibitor 1(C14H10N2O,222.2) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy. | price> |
R-R-0416 | Cyclo(-Gly-Tyr) | Cyclic(glycyl-L-tyrosyl)/Cyclo(-Gly-Tyr)/Cyclo(Gly-Tyr)/Cas.5845-66-9 is a phenolic compound and the main metabolite of the dietary supplement resveratrol. It has been shown to have interactions with cellular transport, as well as the ability to activate a number of proteins that are involved in cellular transport. Cyclic(glycyl-L-tyrosyl) also interacts with hydroxyl groups on proteins and activates them, which may lead to the uptake of these proteins by cells. This interaction between cyclic(glycyl-L-tyrosyl) and hydroxyl groups on proteins may be due to its conformation and affinity for this residue. Cyclic(glycyl-L-tyrosyl) has been reported to inhibit the binding of glucosamine to NUDIX hydrolase, as well as preventing glucosamine from activating NUDIX hydrolase. | price> |