Home > Keywords > DSPE-
| Catalog | name | Description | price |
|---|---|---|---|
| R-DS-0006 | DSPE-PEG-SEARYL-R8 | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glycol-SEARYL-R8 ,Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology. | price> |
| R-DS-0093 | DSPE-PEG-An1 | Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology. | price> |
| R-DS-0007 | DSPE-PEG-EB1 | Liposomes have the advantages of low toxicity,easy preparation,being both the carrier of water-soluble drugs and the carrier of liposoluble drugs,suitable for various drug delivery routes,improving the stability of drugs and achieving targeted drug delivery.However,when liposomes enter the body,due to the specific regulation of plasma conditioner on liposomes,and the nonspecific hydrophobic effect between the cells of the reticuloendothelial system (RES) and liposomes, it is easy to be absorbed and removed by res cells.The half-life of the liposomes is shorter (generally 30 minutes),and the active targeting and stability are poor,Its application is limited to improve its stability in blood circulation,change the biological distribution of liposomes,and have targeted. | price> |
| R-DS-0094 | DSPE-PEG-RMP-7(receptor-mediated permeabilizer-7) | Bradykinin or RMP-7 can not only increase the transport of anticancer drugs,but also promote gene therapy virus, non viral vector,cytokines into human brain tumor tissue,and improve the lethality of tumor cells and tumor cells in the surrounding infiltration area.Bradykinin or RMP-7 not only can selectively open BTB, but also can promote the peripheral opioid receptor agonist loperamide to pass through the normal BBB to produce central analgesic effect.In the animal model of Parkinson disease,RMP-7 can promote cyclosporine A to pass through the blood-brain barrier and make a small dose of cyclosporine A (CSA) produce neuroprotective effect. | price> |
| R-DS-0008 | DSPE-PEG-PF6 | (DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.One of the important characteristics of cell penetrating peptides (CPPS) is that they can carry a variety of bioactive substances with different sizes and properties into cells,including small molecule compounds,dyes,chromatography,nucleic acids (peptide nucleic acids, PNA),proteins,plasmid DNA,siRNA,200 nm liposomes,phage particles and superparamagnetic particles. | price> |
| R-DS-0095 | DSPE-PEG2000-B6 | Cell penetrating peptide (CPP) is a kind of short peptide with strong penetration effect on cell membrane,which can promote cell uptake.Liposome modified by CPP can improve the rate of liposome entry into the cell,which is a new direction of targeted drug delivery carrier research.The amphiphilic block lipid molecule dspe-peg2000-b6 modified by cell osmotic peptide B6 prolonged the blood circulation time,promoted the penetration of nanoparticles (NPS) through BBB,and effectively enriched the drug loaded NPs in glioma lesions. | price> |
| R-DS-0009 | DSPE-PEG-NGR(Asn-Gly-Arg) | Aminopeptidase N is a protease preferentially expressed in vascular endothelial cells.NgR sequence can promote the binding of peptide to aminopeptidase N. | price> |
| R-DS-0096 | LCDX-PEG-DSPE | DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China.Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. | price> |
| R-DS-0010 | DSPE-PEG-APRPG(ALA Pro Arg Pro Gly) | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glyco-APRPG(ALA Pro Arg Pro Gly),APRPG(ALA Pro Arg Pro Gly),namely alanine proline arginine proline glycine sequence,can specifically act on the neovascularization site of tumor,and can be used as a probe to actively target the neovascularization.Aprpg modified liposomes are beneficial to deliver the encapsulated drugs to the vasculogenic vasculature system.The anti-tumor angiogenesis therapy with aprpg modified liposome can target almost all solid tumors actively without drug tolerance.It is a new and efficient anti-tumor method. | price> |
| R-DS-0097 | HE2-PEG2000-DSPE | DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China. Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. | price> |
| R-DS-0011 | DSPE-PEG-VIP(vasoactive intestinal peptide) | Vasoactive intestinal peptide (VIP) is a basic peptide composed of 28 amino acid residues.It belongs to the gastrin/VIP family of gastrointestinal peptide hormones.It is widely distributed in the body,and has high content in the gastrointestinal tract,central and peripheral nerve endings,and has a wide range of physiological functions. | price> |
| R-DS-0098 | DSPE-PEG-FGF-21 | A modified human FGF-21 polypeptide consists of SEQ ID No: 1,SEQ ID No: 2,SEQ ID No: 3,SEQ ID No: 4 with methionine fused at the N-terminal,SEQ ID No: 5,SEQ ID No: 6 or SEQ ID with methionine fused at the N-terminal The modified human FGF-21 peptide has the biological activity of at least one FGF-21,and the unnatural coding amino acid is selected from para substituted phenylalanine,ortho substituted phenylalanine and meta substituted phenylalanine. | price> |
| R-DS-1111 | DSPE-PEG-PTP(KTLLPTP) | PTP (ktllptp) specifically binds to pancreatic cancer cells.Proteomic analysis showed that PTP was targeted by specifically binding to plectin-1,which was mistakenly located on the cell membrane surface during the occurrence of pancreatic cancer. | price> |
| R-DS-0099 | DSPE-PEG-ApoL1 | APOL1 encodes a secreted high density lipoprotein(apolipoprotein L1) which binds to apolipoprotein A-I.Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL.It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body,as well as in reverse cholesterol transport from peripheral cells to the liver.Several different transcript variants encoding different isoforms have been found for APOL1. | price> |
| R-C-0102 | DSPE-PEG2000-RVG29PPP(D-RVG29) | Rabies virus is a natural neurotropic virus.Its capsid contains a neurogenic protein (RVG),which can be specifically recognized by the nicotinic acetylcholine receptor (nAChR) on the surface of nerve cells.Under the action of RVG,rabies virus can easily cross the blood-brain barrier,invade brain tissue and sacred center,and cause rabies,The 29 amino acid sequence of RVG29 (YTIWMPENPRPGTPCDIFTNSRGKRASNG) can also be specifically recognized by nAChR.Liu et al.and Gong et al.T bonded RVG29 to polyamide amine dendrimer (PAMAM) and poly (ethylene amine) (PEI) to support and transport nucleic acid drugs,PAMAM and PE modified by RVG29 could pass through the BBB model,but could deliver cytotoxic anticancer drugs to pus. | price> |
| R-C-0103 | DSPE-PEG2000-OME(D-OME) | To study the targeting effect of a novel ligand RVG29 modified liposome on gliomas in vitro.DSPE-PEG2000-RVG29 PPP (D-RVG29) was prepared by organic phase synthesis method,and liposomes were prepared by membrane dispersion method,The addition of DSPE-PEG2000-OME (D-OME) into the liposome formulation can make D-RVG29 modified liposomes have better particle size and distribution range.The uptake of D-RVG29 modified liposomes by C6 cells is stronger than that of unmodified d-rvg29 liposomes.There is no significant difference in the uptake intensity of the two liposomes by HeLa cells.D-OME can improve the stability of D-RVG29 modified liposomes,D-RVG29 modified liposome has the targeting ability of glioma cells in vitro. | price> |
| R-C-9961 | DSPE-Silane | The reactive group of DSPE silane is amino group,which can couple with any molecule with amino active group,including antibody protein and small molecule.We can also provide dope silane,DPPE silane,DMPE silane and dlpe silane. | price> |
| R-C-9963 | DSPE-OH | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-oh modified amino acids, proteins,peptides,etc.it was used in medical research,drug release,nanotechnology and new materials research,cell culture.And the active compounds such as ligand research,peptide synthesis support,graft polymer,new materials and polyethylene glycol modified functional coating. | price> |
| R-C-9964 | DSPE-Folate | Folate receptor is a cell surface marker of many solid tumors and myeloid leukemia. Folate targeted drug delivery has become an alternative therapy for the treatment and imaging of many cancer and inflammatory diseases.Folate conjugates have low molecular weight and high binding affinity with folate receptor (FR) on cell surface,which can transport various molecular complexes to pathological cells without damaging normal tissues. | price> |
| R-C-9966 | DSPE-Alkyne | Dspe-alk can be used to modify proteins,peptides and other materials or small molecules.Alkynyl(-ALK) can react with copper catalyzed azide in aqueous solution.2-distearoyl-sn-glycoro-3-phosphoethanolamine (DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol, which has hydrophilic and hydrophobic properties.This material can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides. | price> |

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