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R-R-1094 8-Aminoadenosine CAS No.3868-33-5 8-Aminoadenosine (8-NH2-Ado)/CAS No.3868-33-5, a RNA-directed nucleoside analogue, reduces cellular ATP levels and inhibits mRNA synthesis. 8-Aminoadenosine blocks Akt/mTOR signaling and induces autophagy and apoptosis in a p53-independent manner. 8-Aminoadenosine has antitumor activity. price>
R-PL-0062 PBd-b-PDLLA Poly(butadiene(1,2 addition)-b-D,Llactide) PBd-b-PDLLA PDLLA-b-PBd from ruixi Polylactides are a family of biodegradable and bioactive thermoplastic aliphatic polyester. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices. PDLLA polymer is amorphous because the polymer composed randomly by the repeating units from L-lactic acid and D-lactic acid. Therefore, the polymer did not show melting point and has inferior mechanical properties than PLLA, so that the polymer is mainly applied for the coating of suture. price>
R-FAM-012 5-FITC-PEG3-Amine 5-FITC-PEG3-Amine is a fluorescent dye.Its maximum excitation or emission wavelength is 494-517nm.It contains a free amino group.It can react with hydroxysalicylic acid,activated NHS ester and Xiang Group (ketone,aldehyde).The hydrophilic PEG spacer increases the solubility in aqueous medium and reduces the steric hindrance in the binding process. price>
R-R-1095 Chrysomycin A CAS No.82196-88-1 Chrysomycin A (Chr-A)/CAS No.82196-88-1, an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway. price>
R-PL-0063 PBd-b-P4VP Poly(butadiene(1,4 addition)-b-poly(4-vinyl pyridine) PBd-b-P4VP P4VP-b-PBd from ruixi Amphiphilic block copolymer PBd-b-P4VP .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-013 5-FITC-PEG4-COOH Ruixi biological products 5-FITC-PEG4-COOH,polyethylene glycol is the polymer of ethylene oxide hydrolysate,non-toxic,non irritating,widely used in various pharmaceutical preparations.FITC is a kind of green fluorescein derivative with high absorption rate,excellent fluorescence quantum yield and good water solubility.Its isothiocyanate group can react with amino terminal or primary amine of protein to realize protein labeling including antibody and lectin. price>
R-R-1096 N-Feruloyloctopamine CAS No.66648-44-0 N-Feruloyloctopamine is an antioxidant constituent. N-Feruloyloctopamine significantly decreases the phosphorylation levels of Akt and p38 MAPK. price>
R-PL-0064 PIB-b-PtBuMA Poly(isobutylene-b-t-butyl methacrylate) PIB-b-PtBuMA PtBuMA-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PtBuMA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-014 5-FITC-Tetrazine Tetrazine can be used for biorthogonal reactions in many bioimaging and conjugation applications.At present,it has been widely used in protein specific site function interpretation,subcellular structure selective labeling,drug targeted delivery,in vivo animal molecular imaging and preparation of biocompatible materials. price>
R-R-1097 Licoricidin CAS No.30508-27-1 Licoricidin (LCD)/CAS No.30508-27-1 is isolated from Glycyrrhiza uralensis Fisch, possesses anti-cancer activities. Licoricidin (LCD) inhibit SW480 cells (IC50=7.2 μM) by inducing cycle arrest, apoptosis and autophagy, and is a potential chemopreventive or chemotherapeutic agent against colorectal cancer. Licoricidin (LCD) inhibits Lung Metastasis by inhibition of tumor angiogenesis and lymphangiogenesis as well as changes in the local microenvironment of tumor tissues the anticarcinogenic effect. Licoricidin enhanced gemcitabine-induced cytotoxicity in Osteosarcoma (OS) cells by inactivation of the Akt and NF-κB pathways in vitro and in vivo. Licoricidin blocks UVA-induced photoaging via ROS scavenging, limits the activity of MMP-1, it can be considered as an active ingredient in new topically applied anti-ageing formulations. price>
R-PL-0065 PIB-b-PMMA Poly(isobutylene-b-methyl methacrylate) PIB-b-PMMA PMMA-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PMMA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-015 5-diacetate FAM DBCO Ruixi Biotechnology Co., Ltd.is a well-known biotechnology company in China.At present,its products mainly include synthetic phospholipids,PEG derivatives, block copolymers,gold nanoparticles,magnetic nanoparticles,mesoporous silica, reactive fluorescent dyes,fluorescent quantum dots,dot chemistry and macrocyclic ligands,etc. price>
R-R-1098 TD52 dihydrochloride TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity. TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-PL-0066 PIB-b-PDMS Poly(isobutylene-b-dimethylsiloxane) PIB-b-PDMS PDMS-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PDMS.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-016 5-FAM hydrazide HCl Many natural and synthetic molecules contain aldehydes or ketone carbonyls. These carbonyls react with hydrazides to form hydrazones.When the pH value is neutral,the reaction is spontaneous and the hydrazone is very stable.Fam hydrazide is a hydrazide label used to attach fluorescein (a bright dye with 488 nm channel) to carbonyl compounds.We can provide 5-fam hydrazide HCl. price>
R-R-1099 YS-49 monohydrate YS-49 (monohydrate) is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors. price>
R-PL-0067 PIB-b-PCL Poly(isobutylene-b-ε-caprolactone) PIB-b-PCL PCL-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PCL.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-017 5-FAM DBCO Fluorescein (FAM) is one of the oldest fluorescent dyes.The derivatives of fam contain cyclooctynyl (dibenzocyclooctyne, abbreviated as dbco or adibo),which are used for conjugation of azides with copper free,strain promoted cycloaddition (spaac).Fam-dbco can be used to label proteins,peptides,nucleic acids and other molecules containing azide groups.Azide reacts spontaneously with dbco after simple mixing.This reaction does not need any catalyst and is highly efficient. price>
R-R-1100 24-Methylenecycloartanyl ferulate CAS No.469-36-3 24-Methylenecycloartanyl ferulate/CAS No.469-36-3 is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM). price>
R-PL-0068 PIB-b-P4VP Poly(isobutylene-b-poly(4-vinyl pyridine) PIB-b-P4VP P4VP-b-PIB from ruixi Amphiphilic block copolymer PIB-b-P4VP.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>