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Catalog	name	Description	price
R-PL-0149	PNIPAAm-PEG-SH	POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Thiol,PNIPAAm-PEG-SH from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Thiol (PNIPAAm-PEG-SH)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-1111	DSPE-PEG-PTP(KTLLPTP)	PTP (ktllptp) specifically binds to pancreatic cancer cells.Proteomic analysis showed that PTP was targeted by specifically binding to plectin-1,which was mistakenly located on the cell membrane surface during the occurrence of pancreatic cancer.	price>
R-DS-0099	DSPE-PEG-ApoL1	APOL1 encodes a secreted high density lipoprotein(apolipoprotein L1) which binds to apolipoprotein A-I.Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL.It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body,as well as in reverse cholesterol transport from peripheral cells to the liver.Several different transcript variants encoding different isoforms have been found for APOL1.	price>
R-R-1193	Umbralisib hydrochloride CAS No.1532533-78-0	Umbralisib (TGR-1202) hydrochloride/CAS No.1532533-78-0 is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.	price>
R-PL-0150	PNIPAAm-PEG-Biotin	POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Biotin,PNIPAAm-PEG-Biotin from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Biotin (PNIPAAm-PEG-Biotin )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-AS-0006	UCNP-Fe3O4	Fe3O4 nanoparticles are widely used as magnetic recording materials,immobilized enzymes,immunodiagnosis,targeted drugs,catalyst carriers,magnetic microspheres and biological probes.	price>
R-DS-0100	GRF-PEG-DSPE	Growth hormone releasing factor (GRF),also known as growth hormone releasing hormone (GHRH),is a kind of bioactive polypeptide existing in vertebrates.It is synthesized and secreted by hypothalamus and plays an important role in the growth,development and metabolism of vertebrates,As a positive regulator of pituitary growth hormone (GH),it can specifically induce the synthesis and secretion of growth hormone,and increase the level of GH in animal organs.	price>
R-R-1194	CYH33 methanesulfonate CAS No.1494684-33-1	CYH33 methanesulfonate/CAS No.1494684-33-1 is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. CYH33 methanesulfonate inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. CYH33 methanesulfonate has potent activity against solid tumors.	price>
R-PL-0151	P4VP-PEG-NH2	Poly(4-Vinylpyridine)L-polyethylene glycol-Amine,P4VP-PEG-NH2 from ruixi Poly(4-Vinylpyridine)L-polyethylene glycol-Amine(P4VP-PEG-NH2 )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-AS-0007	UCNPS-MPS	Mesoporous silica (m-sio2) nanomaterials have a continuous adjustable mesoporous pore size,controllable size,stable skeleton structure,easy to modify the internal and external surfaces and good biocompatibility.In addition,it can store a variety of drug molecules in its rich channels,which can also play a role in drug release.	price>
R-DS-0101	T-20-PEG-DSPE	Like other peptide drugs,T-20 also has short half-life and poor stability in vivo.In order to obtain anti AIDS polypeptide with long efficacy and high stability,the peptide drug T-20 was modified by PEG (polyethylene glycol) and glycosylation by introducing selective amino acid sites(Cys SH) into the non active domain of the peptide through chemical synthesis,combined with organic synthesis and enzymatic synthesis technology.	price>
R-R-1195	Risovalisib CAS No.1494684-28-4	Risovalisib (CYH33)/CAS No.1494684-28-4 is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. Risovalisib inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. Risovalisib has potent activity against solid tumors.	price>
R-PL-0152	P4VP-PEG-COOH	Poly(4-Vinylpyridine)L-polyethylene glycol-carboxyl,P4VP-PEG-COOH from ruixi Triblock copolymer P4VP-PEG-COOH .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-AS-0008	UCNPS-CS	Chitosan was modified on the surface of nanoparticles by the chemical bonding of N and O atoms in amino and hydroxyl groups with Ag+ which restricted the growth of nanoparticles and prevented their agglomeration.	price>
R-C-0102	DSPE-PEG2000-RVG29PPP(D-RVG29)	Rabies virus is a natural neurotropic virus.Its capsid contains a neurogenic protein (RVG),which can be specifically recognized by the nicotinic acetylcholine receptor (nAChR) on the surface of nerve cells.Under the action of RVG,rabies virus can easily cross the blood-brain barrier,invade brain tissue and sacred center,and cause rabies,The 29 amino acid sequence of RVG29 (YTIWMPENPRPGTPCDIFTNSRGKRASNG) can also be specifically recognized by nAChR.Liu et al.and Gong et al.T bonded RVG29 to polyamide amine dendrimer (PAMAM) and poly (ethylene amine) (PEI) to support and transport nucleic acid drugs,PAMAM and PE modified by RVG29 could pass through the BBB model,but could deliver cytotoxic anticancer drugs to pus.	price>
R-R-1196	AZD8154 CAS No.2215022-45-8	AZD8154/CAS No.2215022-45-8 is a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.	price>
R-PL-0153	P4VP-PEG-MAL	Poly(4-Vinylpyridine)L-polyethylene glycol-Maleimide,P4VP-PEG-MAL from ruixi Triblock copolymer P4VP-PEG-MAL .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-AS-0009	UCNPS-HA	Hyaluronic acid (HA) is a kind of linear macromolecular acidic mucopolysaccharide,which is widely distributed in the extracellular matrix of soft connective tissue.It is composed of glucuronic acid and N-acetylglucosamine.Upconversion luminescent nanoparticles are mainly obtained by doping trivalent rare earth ions in oxides,fluorides,halogenated oxides and other substrates.They are widely used in biological fluorescence labeling and imaging,lasers,solar cells,anti-counterfeiting technology and other fields.	price>
R-C-0103	DSPE-PEG2000-OME(D-OME)	To study the targeting effect of a novel ligand RVG29 modified liposome on gliomas in vitro.DSPE-PEG2000-RVG29 PPP (D-RVG29) was prepared by organic phase synthesis method,and liposomes were prepared by membrane dispersion method,The addition of DSPE-PEG2000-OME (D-OME) into the liposome formulation can make D-RVG29 modified liposomes have better particle size and distribution range.The uptake of D-RVG29 modified liposomes by C6 cells is stronger than that of unmodified d-rvg29 liposomes.There is no significant difference in the uptake intensity of the two liposomes by HeLa cells.D-OME can improve the stability of D-RVG29 modified liposomes,D-RVG29 modified liposome has the targeting ability of glioma cells in vitro.	price>
R-R-1197	PI3K/mTOR Inhibitor-2 CAS No.1848242-58-9	PI3K/mTOR Inhibitor-2/CAS No.1848242-58-9 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity.	price>

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