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R-PL-0158 DSPE-PEG-Phenyl 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Phenyl,DSPE-PEG-Phenyl from ruixi Triblock copolymer DSPE-PEG-Phenyl. Phenyl groups are closely related to benzene and can be viewed as a benzene ring, minus a hydrogen, which may be replaced by some other element or compound to serve as a functional group. Phenyl groups have six carbon atoms bonded together in a hexagonal planar ring, five of which are bonded to individual hydrogen atoms, with the remaining carbon bonded to a substituent. price>
R-DS-0012 DSPE-PEG-THRPPMWSPVWP Liposomes have the advantages of low toxicity,easy preparation,and can be used as the carrier of water-soluble drugs and lipid soluble drugs.It can be used in a variety of drug delivery routes,improve the stability of drugs and achieve targeted drug delivery.However,when liposomes enter the body,due to the specific conditioning effect of plasma opsonin on liposomes and the nonspecific hydrophobic interaction between reticuloendothelial system (RES) cells and liposomes,it is easy to be absorbed and cleared by res cells.The half-life of liposomes in blood circulation is short (generally 30 min),and its active targeting and stability are poor,so its application is limited. price>
R-C-9970 DSPE-cRGD(c(RGDyk)) RGD peptide is a kind of commonly used tumor active targeting peptide,which can directly act on tumor target and form active targeting effect.It can be used for passive targeting,active targeting and drug delivery of micelles and vesicles. DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine)is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes. price>
R-R-1203 Tenalisib R Enantiomer CAS No.1639417-54-1 Tenalisib R Enantiomer (RP6530 R Enantiomer)/CAS No.1639417-54-1 is an R enantiomer of Tenalisib. Tenalisib is a potent and selective PI3Kδ and PI3Kγ inhibitor with IC50 values of 25 and 33 nM, respectively. price>
R-PL-0159 DSPE-PEG-phosphoric acid 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-phosphoric acid, DSPE-PEG-phosphoric acid from ruixi Triblock copolymer DSPE-PEG-phosphoric acid.Phosphoric acid functionalized polyethylene glycol, PEG-phosphate is a surface reactive PEG derivative that can be used to modify metal oxide surface such as titanium dioxide, aluminum oxide, and iron oxide. Phosphoric acid group has high binding affinity toward metal oxide surface. Phosphate PEGcan form self-assembly monolayer (SAM) on these surfaces. price>
R-DS-0013 DSPE-PEG-FSHB Follicle stimulating hormone (FSH) and its receptor (FSHR) binding fragment fshb (qchcgkcdsdstdct,fshl81-95),a peptide fragment of FSH,was used as a targeting head group J.the constructed FSHR targeting drug delivery system had good targeting effect on FSHR positive ovarian cancer cells. price>
R-C-020 DSPE-PEG-Alginate Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection,vaccine delivery,drug delivery and targeted drug use.Phospholipids are hydrophobic and hydrophilic.It can be used to modify protein drugs,peptide compounds,organic small molecule drugs,biomaterials and so on. price>
R-R-1204 MTX-211 CAS No.1952236-05-3 MTX-211 (Mol 211)/CAS No.1952236-05-3 is a dual inhibitor of EGFR and PI3K with IC50 values of <100 nM. MTX-211 can be used for the research of cancer and other diseases. price>
R-PL-0160 DSPE-PEG-NTA 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Nitrilotriacetic acid,DSPE-PEG-NTA((Nitrilotriacetic acid)) from ruixi DSPE PEG NTA is one of ruixi metal chelating phospholipid PEG derivatives that contain an 18 carbon saturated.DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine)is common saturated phospholipid that has high hydrophobicity.Nanocs PEG bridged DSPE PEG NTA is amphilphilic and it can dissolve well in aqueous solution.Because of its good amphilphilic property, this PEG conjugate can be used to synthesize liposome and other biocompatible nanoparticles for drug delivery. price>
R-DS-0014 DSPE-PEG-NYZL1(Asn-Tyr-Glx-Leu) The polypeptide nyzl1 (ASN Tyr GLX Leu) can specifically bind to bladder cancer tissues and cells,and has significant binding specificity. price>
R-R-1205 PF-06843195 CAS No.2067281-51-8 PF-06843195/CAS No.2067281-51-8 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy. price>
R-PL-0161 DSPE-PEG-DNP-PEG-NHS 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-2,4-Dintrophenyl-polyethylene glycol-N-Hydroxysuccinimide,DSPE-PEG-DNP-PEG-NHS from ruixi Pentablock copolymer DSPE-PEG-DNP-PEG-NHS.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DS-0015 DSPE-PEG-HAIYPRH T7 (haiyprh) is a short peptide screened by phage display technology,which can specifically bind to tr with a binding constant as high as 10 nmol-l.moreover, due to different binding sites,endogenous TF will not inhibit,but will promote the specific binding of T7 modified nanoparticles to TfR.Therefore,T7 is more suitable as a target molecule. price>
R-C-S0017 DSPE-Hyd-PEG-Silane DSPE hyd peg silane hydrazone coupling PEG phospholipids is a pH responsive nano liposome The response mode is hydrazone bond breaking. price>
R-R-1206 ETP-45658 CAS No.1198357-79-7 ETP-45658/CAS No.1198357-79-7 is a potent PI3K inhibitor, with IC50s of 22.0 nM, 39.8 nM, 129.0 nM and 717.3 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. ETP-45658 also can inhibit DNA-PK (IC50=70.6 nM) and mTOR (IC50=152.0 nM). ETP-45658 can be used for the research of cancer. price>
R-PL-0163 DSPE-PEG-PFP 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Pentafluorophenyl,DSPE-PEG-PFP from ruixi Triblock copolymer DSPE-PEG-PFP .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DS-0016 DSPE-PEG-SP94 Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.It can be customized to synthesize various kinds of peptide polyethylene glycol (PEG)-DSPE reagents,which are used as active targeting materials,therapeutic materials or auxiliary therapeutic materials,and are widely used in scientific research. price>
R-C-S0018 DSPE-Hyd-PEG-N3 DSPE-PEG-N3 is a kind of click chemical peg reagent.Azido group can easily react with alkynyl group under the catalysis of copper catalyst.It can also react directly with dbco without any catalyst.DSPE (12-distearyl-sn-glycerin-3-phosphate ethanolamine) is a kind of saturated 18 carbon phosphowax,which is often used in the synthesis of liposomes.Polyethylene glycol(PEG)-coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides. price>
R-R-1207 4-Methylbenzylidene camphor CAS No.36861-47-9 4-Methylbenzylidene camphor (4-MBC)/CAS No.36861-47-9 is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy. price>
R-PL-0164 DSPE-PEG-Benzaldehyde 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Benzaldehyde,DSPE-PEG-Benzaldehyde from ruixi Triblock copolymer DSPE-PEG-Benzaldehyde. Benzaldehyde (C6H5CHO) is an organic compound consisting of a benzene ring with a formyl substituent.It is a colorless liquid with a characteristic almond-like odor. The primary component of bitter almond oil, benzaldehyde can be extracted from a number of other natural sources price>