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Catalog | name | Description | price |
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R-R-1223 | BGT226 maleate CAS No.1245537-68-1 | BGT226 (NVP-BGT226 maleate)/CAS No.1245537-68-1 is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ) /mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells. | price> |
R-PN-009 | 6-arm-PLGA-MAL | 6 arm-Poly(D,L-lactide-co-glycolide)-Maleimide,6-arm-PLGA-MAL from ruixi.Maleimide capped 6-arm poly(lactide-co-glycolide) (6-arm PLGA-Maleimide, 6-arm PLGA-Mal) is a multiarm PLGA derivative with amine groups at each terminal of the four arms connected to one pentaerythritol core. The maleimide group selectively reacts with free thiol, SH, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond. 4-Arm PEG-MAL can be used for site specific protein and peptide modification. | price> |
R-C-226 | DSPE-Cyclodextrin | Cyclodextrin (CD) is a general term for a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase (CGT) produced by Bacillus.It usually contains 6-12 D-glucopyranosyl units.Because the glycosidic bond connecting the glucose unit cannot rotate freely,cyclodextrin is not a cylindrical molecule,but a slightly conical ring. | price> |
R-R-1224 | hSMG-1 inhibitor 11e CAS No.1402452-10-1 | hSMG-1 inhibitor 11e/CAS No.1402452-10-1 is a potent and selective hSMG-1 kinase inhibitor with an IC50 of <0.05 nM. hSMG-1 inhibitor 11e shows >900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM). | price> |
R-PN-0010 | 6-arm-PLGA-SH | 6 arm-Poly(D,L-lactide-co-glycolide)-thiol,6-arm-PLGA-SH from ruixi.6-arm poly(lactide-co-glycolide) (4-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification. | price> |
R-C-227 | DSPE-PEG-HMME | Compared with HPD,a mixed porphyrin preparation for clinical application,HMME has the advantages of high photosensitivity,high selective uptake rate of tumor, strong photodynamic effect,low toxicity,no mutagenicity and teratogenicity,etc. it is an ideal new drug for photodynamic cancer treatment. | price> |
R-R-1225 | Sonolisib CAS No.502632-66-8 | Sonolisib (PX-866)/CAS No.502632-66-8, an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity. | price> |
R-PN-0011 | 6-arm-PLGA-NHS | 6 arm-Poly(D,L-lactide-co-glycolide)-N-Hydroxysuccinimide,6-arm-PLGA-NHS from ruixi.6 arm-Poly(D,L-lactide-co-glycolide)(6-arm-PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification. | price> |
R-C-228 | DSPE-PEG-Casein | Casein is a phosphorus protein in animal milk.The structure formula is nh2rcooh, odorless,odorless white to yellow powder with relative density of 1.25-1.31.It is almost insoluble in water,alcohol and ether.It is soluble in dilute alkali solution,alkaline carbonate solution and concentrated acid,and precipitated in weak acid.It is hygroscopic,stable when dry,and harden rapidly when wet.Mainly used as food additives,casein gum,cosmetics,safety matches,pigments,etc. | price> |
R-R-1226 | Vps34-PIK-III CAS No.1383716-40-2 | Vps34-PIK-III/CAS No.1383716-40-2 is an orally active and selective VPS34 inhibitor (IC50=18 nM). Vps34-PIK-III effectively inhibits autophagy and can be used as a molecular tool. vps34-PIK-III is also a PI3K inhibitor that inhibits the expression of genes in liver cancer stem cells (CSCs). | price> |
R-PN-0012 | 6-arm-PLGA-Folate | 6 arm-Poly(D,L-lactide-co-glycolide)-Folic acid,6-arm-PLGA-Folate,6-arm-PLGA-FA from ruixi.6-arm poly(lactide-co-glycolide) (6-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 6-arm PLGA is terminated with hydroxyl group for further modification. | price> |
R-C-229 | DSPE-PEG-Catalase | Poly(z-diol) increases solubility and stability.Long circulating liposomes (LCL) were prepared by modifying the surface of liposomes with polyethylene glycol (PEG),which could prolong the half-life of liposomes,improve its stability in blood circulation,change the biological distribution of liposomes,and have targeting property.Silica modified PEG can modify silicon,glass and other materials,which has good biocompatibility. | price> |
R-R-1227 | PI4KIIIbeta-IN-10 CAS No.1881233-39-1 | PI4KIIIbeta-IN-10/CAS No.1881233-39-1 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM. | price> |
R-PN-0013 | 8-arm-PCL | 8 arm-poly(ε-caprolactone),8-arm-PCL from ruixi.8 arm poly (ε - caprolactone) (8-arm PCL).The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.The end group is OH. | price> |
R-C-230 | DSPE-PEG-Heparin | Heparin sodium salt is a highly sulfated glycosaminoglycan,which is widely used as an injectable anticoagulant.The heparin cascade is widely used as an anticoagulant to accelerate the coagulation rate of heparin.Heparin is used as an anticoagulant,mainly through its enhanced at-III mediated inhibition of coagulation factors,including thrombin and factor Xa interaction with at-iii. | price> |
R-R-1228 | Ginsenoside Rk1 CAS No.494753-69-4 | Ginsenoside Rk1/CAS No.494753-69-4 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis. Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway. | price> |
R-PN-0014 | 8-arm-PLA-NH2 | 8 arm-Poly(D,L-lactide)-amine,8-arm-PLA-NH2 from ruixi.8 arm-Poly(D,L-lactide)-amine(8-arm-PLA-NH2).The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. | price> |
R-C-231 | DSPE-PEG-PAA | Polyacrylic acid is a kind of water-soluble polymer,also known as homopolymer of acrylic acid.PAA is often used in combination with corrosion inhibitor.And it has synergistic effect.Polyacrylic acid is synthesized by free radical polymerization of acrylic acid monomer in water.As a molecular weight regulator,isopropanol can not only make the molecular weight distribution Small and narrow,but also reduce the viscosity and remove the reaction heat. | price> |
R-R-1229 | Rigosertib sodium CAS No.592542-60-4 | Rigosertib sodium (ON-01910 sodium)/CAS No.592542-60-4 is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM. | price> |
R-PN-0015 | 8-arm-PLA-MAL | 8 arm-Poly(D,L-lactide)-Maleimide,8-arm-PLA-MAL from ruixi.8 arm-Poly(D,L-lactide)-Maleimide(8-arm-PLA-MAL).The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. | price> |