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Catalog	name	Description	price
R-M-084	PCN-17 (Er),porous coordination network-17(erbium)	PCN-17 (Er),porous coordination network-17(erbium) from ruixi.Porous coordination networks (PCNs) are promising nanoporous materials in gas separation applications due to their tunable pore sizes, large surface areas, high porosities, and good thermal and mechanical stabilities.	price>
R-R-1506	Avitinib CAS No.1557267-42-1	Avitinib (Abivertinib)/CAS No.1557267-42-1 is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects.	price>
R-OR-407	PEI-g-PLeu	Polyetherimide-g-Poly-L-leucine,PEI-g-PLeu from ruixi.Pei has a strong high temperature stability, even the non reinforced Pei still has a good toughness and strength. Therefore, the superior thermal stability of Pei can be used to make high temperature and heat-resistant devices. It has excellent mechanical properties, electrical insulation, radiation resistance, high and low temperature resistance and wear resistance, and can pass through microwave.	price>
R-R-1507	(1S,2S)-Bortezomib CAS No.1132709-14-8	(1S,2S)-Bortezomib/CAS No.1132709-14-8 is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans.	price>
R-OR-408	PEI-g-Poly-Phenylalanine	Polyetherimide-g-Poly-Phenylalanine,PEI-g-Poly-Phenylalanine(pphe) from ruixi.Phenylalanine has the general properties of amino acids, including reaction with acid and alkali, formation of internal salt, reaction of amino group with 2,4-dinitrofluorobenzene (DNFB) nitrous acid, reaction with halogenated hydrocarbon, esterification of carboxyl group, reaction with anhydride and amide. Phenylalanine can react with ninhydrin to form blue violet red substance.	price>
R-M-086	LZU-79	LZU-79 is a large-size, high-quality single crystal COF material.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1508	hnRNPK-IN-1 CAS No.2313528-04-8	hnRNPK-IN-1/CAS No.2313528-04-8 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4.6 μM and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter. hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities.	price>
R-OR-409	4-arm-PEG-PLL	4 arm-Polyethylene glycol-Poly-L-Lysin,4-arm-PEG-PLL from ruixi.4-arm-peg-pll is a kind of star copolymer.A polymer with long branched chains extending at least two radial branched chains from each branching point. Also known as star branched polymer or star block polymer II, it is usually composed of a linear polymer with a very narrow molecular weight and an appropriate multifunctional linker.	price>
R-M-087	LZU-111	LZU-111 is a three-dimensional imine type single crystal COFS material with large size and high quality.LZU-111 has a rare lon-b-c3 chiral topology, a high specific surface area of 2120 m2g-1 and a pore volume of 0.918 cm3 g-1.	price>
R-R-1509	Nonactin CAS No.6833-84-7	Nonactin/CAS No.6833-84-7 is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+. Nonactin is able to uncouple the oxidative phosphorylation (OXPHOS) of mitochondria. Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin. Nonactin inhibits the surface expression of endogenous HSP60.	price>
R-OR-500	PLL-HA	Poly-L-Lysin-hyaluronic acidn,PLL-HA from ruixi.Poly-L-Lysin-hyaluronic acid,PLL-HA from ruixi.Hyaluronic acid, with its unique molecular structure and physical and chemical properties, shows many important physiological functions in the body, such as lubricating joints and regulating the permeability of blood vessel walls. Especially, hyaluronic acid has a special function of water retention.	price>
R-M-088	DUT-68,Dresden University of Technology-68	DUT-68,Dresden University of Technology-68 from ruixi.Dut-68 has a more complex hierarchical pore system, including rhombic cubic octahedral mesopores surrounded by cubic octahedrons, square antiprism and octahedral microcavities.	price>
R-R-1510	CSRM617 hydrochloride CAS No.1353749-74-2	CSRM617 hydrochloride/CAS No.1353749-74-2 is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 hydrochloride induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the prostate cancer mouse model.	price>
R-OR-501	Cu-TCPP，Porphyrin metal organic framework	Cu-TCPP，Porphyrin metal organic framework,Cu-Meso-Tetra(4-carboxyphenyl)porphine from ruixi.Cu TCPP is an ultra-thin two-dimensional metal organic framework and a two-dimensional MOF. It can selectively generate 1O2 and kill tumor cells in tumor microenvironment. Cu TCPP nano tablets can destroy tumor efficiently and selectively. Cu TCPP is very effective in cell and in vivo experiments.	price>
R-M-089	Dut-5,Dresden University of Technology-5	Dut-5,Dresden University of Technology-5 from ruixi.Dut-5 has a high permanent porosity and a specific pore volume of 0.81 cm3 g−1.At 40 bar and−196℃, the maximum hydrogen excess adsorption capacity is 3.3 wt.%.	price>
R-R-1511	Rabeprazole-d4 sodium	Rabeprazole-d4 (sodium) is the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.	price>
R-OR-502	USTC-8(Cu)	USTC-8(Cu),Porphyrin based organometallic framework,USTC-8(Cu) from ruixi.Owing to the structural controllability, pore modification and unique semiconductor property of metal-organic frameworks (MOFs), the investigation on MOFs as efficient photocatalysts for hydrogen production from water splitting under UV, visible or even NIR light irradiation have made great progress.	price>
R-M-090	Dut-69,Dresden University of Technology-69	Dut-69,Dresden University of Technology-69 from ruixi.Dut-69 is the first example of a Zr based MOF with 10 connected SBUs.Dut-69 has a BCT topology with octahedral cages and channels running along a crystallographic direction.	price>
R-R-1512	Larotaxel CAS No.156294-36-9	Larotaxel (XRP9881)/CAS No.156294-36-9 is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel.	price>
R-OR-503	Pt-TCPP	Pt-Meso-Tetra(4-carboxyphenyl)porphine,Pt-TCPP from ruixi.Pt TCPP is a kind of metal organic frame material.Metal organic frameworks (MOFs) are organic-inorganic hybrid materials with intramolecular pores formed by self-assembly of organic ligands and metal ions or clusters through coordination bonds.In MOFs, the arrangement of organic ligands and metal ions or clusters has obvious directionality, which can form different framework pore structures, thus showing different adsorption properties, optical properties, electromagnetic properties and so on. MOFs has great development potential and attractive prospect in modern materials science.	price>

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