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Catalog | name | Description | price |
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R-M-142 | FMOC-ARG(ME,PBF)-OH,cas:1135616-49-7 | FMOC-ARG(ME,PBF)-OH is a kind of drug peptide.Nω-Methylation is a widespread post-translational modification of Arg-containing proteins.Arg(Me) can be conveniently introduced during the Fmoc-SPPS of model peptides using this derivative. | price> |
R-M-183 | WT1 Peptide | WT1,Wilms tumor 1 Peptide has a potential role in transcriptional regulation by recognizing and binding to the DNA sequence 5-CGCCCCCGC-3. Defects in WT1 are the cause of nephropathy (Frasier and Denys-Drash syndromes) and genito-urinary dysplasia in Wilms tumor syndrome.Data on WT1 peptide vaccine-treated patients with immunological and/or clinical response have been accumulated. MDS and acute myeloid leukemia were the major target diseases to provide proof of concept for the therapeutic potential of the WT1 peptide vaccine. WT1 vaccination-induced clinical responses or usefulness were also shown for chronic myeloid leukemia, multiple myeloma, and acute lymphoblastic leukemia, as well as various types of solid cancers.Patients with hematologic malignancies have minimal residual disease after chemotherapy or allogeneic hematopoietic stem cell transplantation, which can be treated by WT1 peptide vaccine. | price> |
R-R-1564 | (Rac)-CCT 250863 CAS No.1364269-06-6 | (Rac)-CCT 250863 (compound rac-21)/CAS No.1364269-06-6 is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide. | price> |
R-OR-552 | PCL-PEG-Mannose | Poly(ε-caprolactone)-Polyethylene glycol-Mannose,PCL-PEG-Mannose from ruixi.Polyethylene glycol (PEG) is one of the most frequently used polymers for coating nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability.Synthesis of PEG conjugates (peptide, folate, biotin, mannose, etc.), imaging peg conjugates (coumarin, coumarin, coumarin, etc.), near-infrared dyes, etc.) and delivery of PEG conjugates (doxorubicin, paclitaxel and other hydrophobic low molecular weight drugs). | price> |
R-UDP650 | DSPE-PEG modified Upconverting Nanoparticle | DSPE-PEG modified Upconverting(UCNPS) Nanoparticle, absorbance 980 nm,DSPE-PEG modified Upconverting Nanoparticle from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues. DSPE peg coated up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system. | price> |
R-M-143 | L-Tryptophan Methyl Ester Hydrochloride(HCl),cas:7524-52-9 | L-tryptophan methyl ester hydrochloride (HCl) is one of the drug peptides.Polypeptides are compounds formed by linkingα-amino acids with peptide bonds.They are intermediate products of protein hydrolysis.The compound formed by dehydration and condensation of two amino acid molecules is called dipeptide, and so on.A compound usually formed by dehydration and condensation of 10-100 amino acid molecules is called polypeptide. | price> |
R-M-184 | WRN Peptide | Werner syndrome ATP-dependent helicase (WRN) is essential for the formation of DNA replication focal centers and associates with foci elements generating binding sites for RPA. Defects in WRN are a cause of Werner syndrome, a multiple age-related disorders, including atherosclerosis, cancer, diabetes and osteoporosis. | price> |
R-R-1565 | NSC 48160 CAS No.6640-90-0 | NSC 48160/CAS No.6640-90-0 inhibits the growth of the pancreatic cancer cells with IC50s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders. | price> |
R-OR-553 | PLGA-PEG-Galactose | Poly(lactic-co-glycolic acid)-Polyethylene glycol-Galactose,PLGA-PEG-Galactose from ruixi.Polyethylene glycol (PEG) is one of the most frequently used polymers for coating nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability.Synthesis of PEG conjugates (peptide, folate, biotin, mannose, etc.), imaging peg conjugates (coumarin, coumarin, coumarin, etc.), near-infrared dyes, etc.) and delivery of PEG conjugates (doxorubicin, paclitaxel and other hydrophobic low molecular weight drugs). | price> |
R-XS10476 | PEG-COOH modified water soluble Upconverting Nanoparticle | PEG-COOH Upconverting Nanoparticles(UCNPS), Excitation 980 nm,PEG-COOH modified water soluble Upconversion Nanoparticles from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues. Peg COOH coated up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system. | price> |
R-M-144 | N-Hydroxysulfosuccinimide sodium salt,cas:106627-54-7 | N-Hydroxysulfosuccinimide sodium salt is a hydrophilic ligand for the preparation of active esters, which can be used for crosslinking agents.Used as a protein cross linker Carboxyl containing proteins will form an acyl amino ester using a carbodiimide. The acyl amino ester is primary or secondary amine reactive Sulfonated NHS esters improve a compounds water solubility. | price> |
R-M-185 | WNK4 Peptide | Ser/Thr-protein kinase WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter SLC12A3 by phosphorylation, which prevents membrane trafficking of SLC12A3. WNK4 also inhibits the renal potassium channel KCNJ1 via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 acts as a molecular switch that can vary the balance between NaCl reabsorption and K+ secretion to maintain integrated homeostasis. WNK4 is exclusively present in intercellular junctions in th edistal convoluted tubule and in both the cytoplasm and intercellular junctions in the cortical collecting duct. Defects in WNK4 are a cause of pseudohypoaldosteronism type II (PHAII). | price> |
R-R-1566 | Cantrixil CAS No.2135511-22-5 | Cantrixil (TRX-E-002-1)/CAS No.2135511-22-5, an active enantiomer of TRX-E-002, is a second-generation super-benzopyran (SBP) compound. Cantrixil increases phosphorylated c-Jun levels resulting in caspase-mediated apoptosis in ovarian cancer cells. Cantrixil has potent pan anti-cancer activity against a broad range of cancer phenotypes. | price> |
R-OR-554 | PLA-PEG-Galactose | Poly(D,L-lactide)-Polyethylene glycol-Galactose,PLA-PEG-Galactose from ruixi.Polyethylene glycol (PEG) is one of the most frequently used polymers for coating nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability.Synthesis of PEG conjugates (peptide, folate, biotin, mannose, etc.), imaging peg conjugates (coumarin, coumarin, coumarin, etc.), near-infrared dyes, etc.) and delivery of PEG conjugates (doxorubicin, paclitaxel and other hydrophobic low molecular weight drugs). | price> |
R-SD540 | Streptavidin coated Upconverting Nanoparticle | Streptavidin coated Upconverting Nanoparticle, absorbance 980 nm,Streptavidin coated Upconverting Nanoparticle from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues. Streptavidin coated up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system. | price> |
R-M-145 | Glycyl-L-glutamine monohydrate,cas:13115-71-4 | Glycyl-L-glutamine monohydrate,Glycyl-L-glutamine from ruixi.Glycyl-L-glutamine is used as a component in pharmaceuticals, cosmetics and food products. It is also used as an ingredient of cell culture medium and as laboratory reagent.Glycyl-L-glutamine is an odorless crystalline white solid at standard temperature and pressure. Since Glycyl-L-glutamine does not react with water or oxygen, it is not classified as flammable or as an oxidizer or explodes.The substance will not self-ignite. | price> |
R-M-186 | VHL Peptide | VHL,Von Hippel Lindau is involved in the ubiquitination and subsequent proteasomal degradation of hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Defects in VHL are the cause of different types of cancers (pheochromocytoma, von Hippel-Lindau disease) and erythrocytosis. | price> |
R-R-1567 | GSK-843 CAS No.1601496-05-2 | GSK-843/CAS No.1601496-05-2 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. GSK-843 can be used for the research of inflammation. | price> |
R-OR-555 | PCL-PEG-Galactose | Poly(ε-caprolactone)-Polyethylene glycol-Galactose,PCL-PEG-Galactose from ruixi.Polyethylene glycol (PEG) is one of the most frequently used polymers for coating nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability.Synthesis of PEG conjugates (peptide, folate, biotin, mannose, etc.), imaging peg conjugates (coumarin, coumarin, coumarin, etc.), near-infrared dyes, etc.) and delivery of PEG conjugates (doxorubicin, paclitaxel and other hydrophobic low molecular weight drugs). | price> |
R-UPM365 | PEG-Maleimide Upconverting Nanoparticles | PEG-Maleimide Upconverting Nanoparticles(UCNPS), absorbance 980 nm,PEG-Maleimide Upconverting Nanoparticles from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues. Peg maleimide coated up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system. | price> |