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R-M-154 XPC Peptide Xeroderma pigmentosum group C-complementing protein (XPC) is involved in DNA excision repair by recognizing DNA damage and altering chromatin structure for damage-processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C characterized by solar sensitivity and skin cancer predisposition. price>
R-M-195 Trypsin Substrate Peptide This peptide is a fluorogenic substrate for trypsin, a peptidase S1 family members that cleaves at Arg-Xaa and Lys-Xaa sites within proteins. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm). price>
R-R-1576 Taurodeoxycholic acid CAS No.516-50-7 Taurodeoxycholic acid/CAS No.516-50-7, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. price>
R-OR-564 mPEG2K-hyd-PEI25K methoxy polyethylene glycol 2k-hydrazone-Polyethyleneimine,mPEG2K-hyd-PEI25K from ruixi.One end of the hydrazone bond is connected with the methoxy polyetherylene glycol, and the other end is connected with the polyetherimide.Polyetherimide is called PEI for short. Pei has a strong high-temperature stability, so the superior thermal stability of Pei can be used to make high-temperature and heat-resistant devices. Pei also has good flame retardancy, chemical resistance and electrical insulation properties. price>
R-M-155 Tyr-Specific Protein Kinase Inhibitor Peptide This peptide is an inhibitor for tyrosine protein kinases such as EGFR and Src subfamily members (IC50=7.5 mM for pp60 v-src).The sequence corresponds to residues 140-160 of the proto-oncogene tyrosine protein kinase Src (c-Src). price>
R-M-196 Ser25 PKC [19-31] Peptide This is a peptide derived from the pseudosubstrate regulatory domain of PKC α residues (19-31) with alanine being replaced with serine at position 25.This peptide is a pseudosubstrate for a number of serine/threonine kinases, including protein kinase A (PKA), protein kinase B (PKB), protein kinase C (PKC), protein kinase CHK1, and glycogen synthase kinase 3 (GSK3) different isoforms. The peptide sequence is derived from the residues 19-31 of human protein kinase C isoforms alpha and beta, which contains the R-X-X-S/T consensus motif for Ser/Thr kinases that phosphorylate the Ser25 within this peptide. price>
R-R-1577 Piclidenoson CAS No.152918-18-8 Piclidenoson (IB-MECA)/CAS No.152918-18-8 is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19. price>
R-OR-565 Hemin-NHS Hemin Chloride-N-hydroxysuccinimide,hemin-NHS from ruixi.Heme chloride is the purification form of natural heme in vitro. Hemin is widely used in medicine, food, chemical industry, health products, construction and cosmetics industry. In the pharmaceutical industry, it can be used as semi synthetic bilirubin raw material, and can be used to prepare anticancer drugs; in clinical, it can be made into heme iron supplement; in the cosmetics industry, it is an important raw material price>
R-M-156 Tyrosine Protein Kinase Substrate Peptide This peptide is a substrate for tyrosine protein kinases such as EGFR and Src subfamily members. The sequence derives from the residues 412-422 of the Tyr-419 tyrosine autophosphorylation site of the proto-oncogene tyrosine protien kinase Src (c-Src). price>
R-M-197 S6 Kinase Substrate [229-239] Peptide Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents and mitogens and the dephosphorylation by growth arrest. The 229-239 peptide contain two phosphorylation sites, Ser235 and Ser236. price>
R-R-1578 Citreoviridin CAS No.25425-12-1 Citreoviridin/CAS No.25425-12-1, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells. price>
R-OR-566 PLGA25K-PEG5K-choline Poly(lactic-co-glycolic acid)25k-polyethylene glycol5k-choline, PLGA25000-PEG5000-choline from ruixi.Choline is a positively charged tetravalent base, which is the component of all biofilms and the precursor of acetylcholine in cholinergic neurons. Choline promotes brain development, memory and information transmission. price>
R-M-157 [Val5] Angiotensin II Peptide Angiotensin II is the physiologically active form and regulates both the volume and the mineral balance in the body through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Angiotensin II is a natural ligand for angiotensin II type 1 receptors. [Val5] Angiotensin II peptide is an angiotensin II analog that is an agonist for AT1 angiotensin receptors. price>
R-M-198 KL-1 Peptide KL-1 Peptide corresponds to aa 185-196 of Kit Ligand (KITLG, KL) also known as Stem Cell Factor (SCF). A soluble form (sKITLG) is produced by proteolytic processing of transmembrane KITLG at aa190. KL-1 peptide is used as a substrate for proteases such as furin. SCF stimulates the proliferation of mast cells, augments the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture, and mediates cell-cell adhesion. SCF acts synergistically with other cytokines such as interleukins. price>
R-R-1579 Perhexiline maleate CAS No.6724-53-4 Perhexiline maleate/CAS No.6724-53-4 is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline maleate induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline maleate can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline maleate can be used in the research of cancers, and cardiovascular disease like angina. price>
R-DZ0190 Chitosan-β-Cyclodextrin Chitosan-β-Cyclodextrin, Chitosan-β-CD from ruixi.Chitosan is a product of N-deacetylation of chitosan. Chitin, chitosan and cellulose have similar chemical structure. It is widely used in food additives, cosmetics, antibacterial agents, medical fibers, medical dressings, artificial tissue materials, drug slow-release materials, gene transfer carriers, biomedical fields, medical absorbable materials, medical and Many fields such as drug development and other daily chemical industries.β - cyclodextrin is widely used in pharmaceutical excipients and food additives. price>
R-M-158 Cyclo(-Pro-Tyr),CAS:4549-02-4 The host-specific phytotoxin cyclo(Pro-Tyr),CAS:4549-02-4 produced by Alternaria alternata on spotted knapweed is an ideal prototype for creating a safe and an environmentally friendly antiknapweed herbicide. Furthermore, this cyclic dipeptide induced a high degree of phosphorylation of histones. price>
R-M-199 Elastase Substrate Peptide This peptide is a fluorogenic substrate for elastase, a peptidase S1 family member that cleaves at Ala-Xaa sites within proteins, including elastin. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm). price>
R-R-1580 Mensacarcin CAS No.808750-39-2 Mensacarcin/CAS No.808750-39-2, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs). price>
R-OR-567 CHOL-PEG2000-NAcPGPv Cholesterol-polyethylene glycol2k-NAcPGPv,CHOL-PEG2000-NAcPGPv from ruixi.N-acetylproline-glycine-proline is a matrix derived chemokine produced by collagen degradation. price>