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Catalog	name	Description	price
R-M-159	Cyclo(-Leu-Pro),CAS:2873-36-1	Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry. Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite and it has been isolated from various bacterial and fungal species including Streptomyces. It is active against twelve strains of vancomycin-resistant enterococci (VRE) and also inhibits growth of K562, HL-60, and U937 leukemia cells in a concentration-dependent manner when used at concentrations of 1-500 µg/ml.	price>
R-M-200	Cathepsin L Substrate Peptide	This peptide is a fluorogenic substrate for cathepsin L and plasmin, peptidase C1 family members that cleave at Arg-Xaa and Lys-Xaa sites within proteins. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm).	price>
R-R-1581	Ecdysone CAS No.3604-87-3	Ecdysone (α-Ecdysone)/CAS No.3604-87-3, a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979).	price>
R-OR-5677	NGR-PEG2K-PLA	Poly(D,L-lactide)-Polyethylene glycol2k-NGR，Sequence number of NgR peptide:Asparagic acid-Arginine-Glycine，NGR-PEG2K-PLA from ruixi.NgR peptide is a kind of target peptide which can bind to CD13 receptor on tumor neovascular endothelial cells. It can locate liposome in tumor tissue, make the drugs in liposome concentrate in tumor site, so as to improve tumor effect.	price>
R-M-160	Cyclo(-Leu-Phe),CAS: 7280-77-5	Cyclo(L-phenylalanyl-L-leucyl),Cyclo(-Leu-Phe) is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer). It has a role as a metabolite. This diketopiperazine is converted into the antibacterial dehydropeptide albonoursin by cyclo(Leu-Phe) oxidase from S. albulus KO-23.	price>
R-M-201	CaMKII Substrate Peptide	This peptide is a substrate (Km = 7.5 mM) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent.	price>
R-R-1582	Melatonin-d4 CAS No.66521-38-8	Melatonin-d4/CAS No.66521-38-8 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.	price>
R-OR-568	PAE10K-PEG5K-glutamine(Connected by carboxyl group)	poly(β-amino esters)10k-polyethylene glycol5k-glutamine,PAE10000-PEG5000-glutamine(Connected by carboxyl group) from ruixi.Glutamine, scientific name 2-amino-4-carbamoyl butyric acid, English glutamine (Gln).Poly (β - aminoester) is a kind of drug carrier with pH sensitivity, low toxicity, simple synthesis method and various structures. It has a broad medical prospect in tumor targeting drug system.	price>
R-M-161	cyclo-GP,CAS :3705-27-9	Cyclo(Gly-Pro) has been detected in rat brain. In the passive avoidance test in rats, synthetic cycloprolylglycine showed 76% antiamnesic activity.Cyclo(Gly-L-Pro) is a cyclodipeptide isolated from the roots of Panax notoginseng (Burk.)F.H.Chen. Cyclo(Gly-L-Pro) was reported to inhibit TNF-α release, IL-1β and IL-6 mRNA expression and NO production.	price>
R-M-202	Calcineurin Substrate Peptide	The calcineurin substrate peptide corresponds to a sequence from the regulatory RII subunit of cAMP-dependent protein kinase. Calcineurin substrate can be used for assaying protein phosphatase-2B (calcineurin) activity.	price>
R-R-1583	MYC-RIBOTAC	MYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) to MYC internal ribosome entry site (IRES).MYC-RIBOTAC contains a MYC mRNA-binder and a small molecule that recruits and locally activates RNase L1 and decreases the mRNA and protein expression levels of MYC, induces apoptosis. MYC-RIBOTAC can be used for anticancer research.	price>
R-DZP003	Poly(DMA-co-NAS)MW:7500-8000	Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc.	price>
R-M-162	Cyclo(-Leu-Trp),CAS：15136-34-2	The diketopiperazine cyclo(Leu-Trp) has been isolated by Minamiura et al. from casein hydrolyzate by bacterial proteinase. It is one of the bitter compounds detected in cheese. Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria (MICs = 125-1000 µg/ml) and fungi (MICs = 8-64 µg/ml), and it inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 µM). Cyclo(L-Leu-L-Trp) is a bitter tastant that can rapidly permeate rat taste cell membranes ex vivo when used at a concentration of 1 mM. It also acts as a melatonin receptor agonist in X. laevis melanophores, inhibiting cAMP accumulation when used at a concentration of 20 µM, an effect that is blocked by the melatonin receptor antagonist luzindole (Cay-15998).	price>
R-M-203	Autocamtide-2 Peptide	Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the Thr-286 autophosphorylation site of the alpha subunit of CaMKII. Autocamtide-2 contains the R-X-X-S/T consensus site surrounded by basic residues for improved binding to phosphocellulose. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaMKII phosphorylates Autocamtide-2 with a Km of 2 uM whereas protein kinase C (PKC) has a Km > 50 uM and protein kinase A (PKA) has no activity.	price>
R-M-484	Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluor	Acetyl-AAVALLPAVLLALLAP-IETD-CHO, the potent reversible caspase-8 inhibitor IETD-CHO is rendered cell-permeable by attaching a non-polar CPP corresponding to the Kaposi fibroblast growth factor (FGF) signal peptide sequence.	price>
R-R-1584	Maduramicin ammonium CAS No.84878-61-5	Maduramicin ammonium (Maduramycin ammonium)/CAS No.84878-61-5 is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection. Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.	price>
R-OR-569	Ethylenediamine glycyrrhetinic acid	Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc.	price>
R-M-163	Ac-Lys-N-Me-Leu-Val-N-Me-Phe-Phe-NH₂ trifluoroacetate salt	Membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis.Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 (CAS# 461640-33-5) is a useful research chemical compound.	price>
R-M-204	CREBtide Peptide	This eptide is a synthetic substrate for protein kinase A (PKA) with a Km = 3.9 uM. The peptide sequence corresponds to residues 123-135 of human cAMP-response element-binding protein (CREB) and contains the Ser-133 phosphorylation site for CaMK1, CaMK2 and CaMK4.	price>
R-R-1585	BETd-260 CAS No.2093388-62-4	BETd-260 (ZBC 260)/CAS No.2093388-62-4 is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. BETd-260 potently suppresses cell viability and robustly induces apoptosis in hepatocellular carcinoma (HCC) cells.	price>

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