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R-M-266 Cyclo(-Gly-Phe),CAS :10125-07-2 Cyclo(-Gly-Phe),CAS :10125-07-2 is used to study the thermodynamics of protein unfolding. It is also able to cause gelation in a wide variety of organic fluids, including edible oils, glyceryl esters, alcohols, and aromatic molecules. price>
R-M-277 TRH Free Acid Peptide TRH free acid is derived from Thyrotropin Releasing Hormone (TRH), and the latter could cause the release of Thyroid Stimulating Hormone (TSH) from the pituitary . They are different functionally, such as stimulation of GTPase depended on occupancy of the TRH receptor; half-maximal increases in GTPase activity required 46 nM TRH and 25 nM [N3-methyl-His]TRH, but the TRH free acid was inactive.Regulates the synthesis of TRH in the Pituitary gland and acts as a neurotransmitter in the nervous system. price>
R-R-1641 Ajoene CAS No.92285-01-3 Ajoene/CAS No.92285-01-3, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities. price>
R-M-267 Cyclo(-Ala-Gly),CAS:4526-77-6 Cyclo(-Ala-Gly),CAS:4526-77-6 from ruixi.Diketopiperazine and monoalkyldiketopiperazines such as cyclo-(Ala-Gly) and cyclo-(Gly-Leu) underwent a stereocontrolled transannular rearrangement (after activation by N-acylation or N-Bocylation) yielding 4-hydroxy-3-pyrrolin-2-ones. price>
R-M-278 TP508 Peptide ,CAS:121341-81-9 TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibroblasts. price>
R-R-1642 Reveromycin A CAS No.134615-37-5 Reveromycin A/CAS No.134615-37-5, a benzoquinoid antibiotic isolated from the genus Streptomyces, is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity. price>
R-M-268 Cyclo(-Gly-Gly),CAS:106-57-0 Cyclo(-Gly-Gly),2,5-Piperazinedione(CAS:106-57-0)can be used as an intermediate in the preparation of various pharmaceutical and biologically active compounds. It can be used in the synthesis of dipeptide isosteres by cross-metathesis. price>
R-M-279 TNF-alpha Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection. price>
R-R-1643 3-Dehydrotrametenolic acid CAS No.29220-16-4 3-Dehydrotrametenolic acid/CAS No.29220-16-4, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity. price>
R-M-269 Cyclo(-Gly-Trp) ,CAS :7451-73-2 Cyclo(-Gly-Trp),Cyclo(-glycyl-tryptophyl) from ruixi.Cyclo(glycyltryptophyl) is a member of indoles. It has a role as a metabolite. price>
R-M-280 TLR4 Peptide Toll-like receptor family (TLR) has a fundamental role in pathogen recognition and activation of innate immunity. TLRs recognize pathogen-associated molecular patterns (PAMP) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 acts via MYD88, TIRAP and TRAF6 to lead to NFkB activation, cytokine secretion and inflammatory response. TLR4 is highly expressed in placenta, spleen and peripheral blood leukocytes. price>
R-R-1644 Ceramide C6-d7 CAS No.2692624-22-7 Ceramide C6-d7/CAS No.2692624-22-7 is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells. price>
R-M-270 Cyclo(-Glu-Glu),CAS: 16691-00-2 Cyclo(-Glu-Glu),CAS:16691-00-2 from ruixi.Both chiral OFm monosubstituted cyclo­(l-Glu-l-Glu) and cyclo­(d-Glu-d-Glu) display a robust gelation ability in a variety of organic solvents and water. In contrast to an individual enantiomer,their racemate can form rapidly recoverable thixotropic hydrogels with a remarkably shorter thixotropic recovery time. This unexpected thixotropic behavior is induced by the random arrangement of d-and l-enantiomers in the cell units, leading to the formation of pseudoracemate, noncrystalline self-assemblies in the resulting 3D fibrous network. price>
R-M-281 TIMP-3 Peptide Tissue inhibitor of metalloproteinases 3 (TIMP-3) binds to metalloproteinases such as collagenases and irreversibly inactivates the proteases. TIMP-2 is involved in the extracellular matrix remodeling by binding to MMP-1, -2, -3, -7, -9, -13, -14 and -15. Defects in TIMP-3 are the cause of Sorsby fundus dystrophy (SFD), a macular disorder leading to vision loss. price>
R-R-1645 C24:1-Ceramide CAS No.54164-50-0 C24:1-Ceramide/CAS No.54164-50-0 is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. price>
R-M-271 Vanilloid Receptor Subtype 1 Peptide Vanilloid receptor subtype 1 (VR1),Vanilloid Receptor Subtype 1 Peptide from ruixi.Vanilloid Receptor is a non-selective Cz Channel for the detection of lethal chemical and thermal stimuli. price>
R-M-282 TRH Peptide TRH Peptide,Thyrotropin-Releasing Hormone Peptide from ruixi.Thyrotropin-releasing hormone (TRH) is a tripeptide hormone secreted by the hypothalamus that stimulates the release of thyrotropin. This tripeptide is involved in the regulation of the hypothalamic pituitary-thyroid axis; it stimulates the synthesis and release from the anterior pituitary of thyrotropin (TSH) and prolactin. price>
R-R-1646 Droloxifene CAS No.82413-20-5 Droloxifene/CAS No.82413-20-5, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. Droloxifene shows antiestrogenic and anti-implantation effects. Droloxifene induces p53 expression and apoptosis in MCF-7 cells. Droloxifene prevents bone loss in ovariectomized rats . price>
R-M-272 Val4-DDAVP Acetate Peptide Val4-DDAVP can be used to prepare samples for qualitative detection of desmopressin in plasma by using liquid chromatography-electrospray tandem mass spectrometry. Val4-DDAVP is a V1 antagonist that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It can also stimulate three acid-base transporters and hence increases the capability of the cell to regulate pHI. price>
R-M-283 FLAG Epitope Peptide acetate salt The FLAG Epitope Peptide consists of eight amino acids (DYKDDDDK) and represents a versatile fusion tag for the purification of recombinant proteins. It can be enzymatically removed with enterokinase which cleaves C-terminally to the tag sequence. The peptide is commonly used for the elution of immunoaffinity chromatography-purified recombinant proteins. price>