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Catalog	name	Description	price
R-R-1665	Seribantumab CAS No.1334296-12-6	Seribantumab (MM 121)/CAS No.1334296-12-6 is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models.	price>
R-M-509	Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)	Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3.PARP cleavage occurs at the onset of apoptosis.The peptide aldehyde was able to attenuate apoptotic events in vitro.	price>
R-R-1666	VTP50469 CAS No.2169916-18-9	VTP50469/CAS No.2169916-18-9 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity.	price>
R-M-510	Ac-DEVD-AMC	Ac-DEVD-AMC(CAS :169332-61-0) is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.	price>
R-R-1667	EPZ020411 CAS No.1700663-41-7	EPZ020411/CAS No.1700663-41-7 is a selective inhibitor of PRMT6 with an IC50 of 10 nM, has >10 folds selectivity for PRMT6 over PRMT1 and PRMT8. EPZ020411 can be used for the research of cancer.	price>
R-M-511	Caspase-3 Inhibitor III	Caspase-3 Inhibitor III,Ac-DEVD-CMK(Caspase-3 Inhibitor III) is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems.	price>
R-R-1668	Nampt-IN-3 CAS No.2121591-52-2	Nampt-IN-3 (Compound 35)/CAS No.2121591-52-2 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death.	price>
R-M-512	Ac-Asp-Glu-Val-Asp-pNA	Ac-Asp-Glu-Val-Asp-pNA,Ac-DEVD-pNA(CAS : 189684-50-2) from ruixi.The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm.	price>
R-R-1669	Physalin F CAS No.57423-71-9	Physalin F/CAS No.57423-71-9 is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection.	price>
R-M-294	γ-CD-MOF	γ-CD-MOF,γ-cyclodextrin-metal organic framework from ruixi.γ-CD-MOF is a biocompatible drug carrier, and has high antibiotic delivery ability for infection treatment. It has broad application prospects in gas storage and separation, drug delivery, environmental purification and sensing.Among them, γ - cd-mof-k has the added value of easy processing and "green", which makes γ - cd-mof-k a good choice for formaldehyde relative air purification.	price>
R-M-513	Ac-Asp-Met-Gln-Asp-AMC	Ac-Asp-Met-Gln-Asp-AMC is a fluorogenic substrate for Caspase 3 (Apopain). Caspase 3 is a cysteine protease that is rapidly activated during apoptosis and that cleaves several substrates, including poly(ADP-ribose) polymerase (PARP). Caspase 3 is activated by Caspases 8, 9 and 10 and cleaves and activates caspase 6 and 7. Caspase 3 cleaves the amyloid precursor protein (APP) contributing to Amyloid beta formation and has been implicated in Alzheimer’s disease and proposed as a target for drug discovery. Ac-DMQD-AMC is reported to be a more specific caspase-3 substrate than Ac-DEVD-AMC.	price>
R-R-1670	9-Methoxycamptothecin CAS No.39026-92-1	9-Methoxycamptothecin (MCPT)/CAS No.39026-92-1, isolated from Camptotheca acuminata, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer.	price>
R-M-295	MOF-525-Co（100nm）	MOF-525-Co,metal organic framework-525-cobalt from ruixi.Metal organic framework material (MOF) is a new porous material with regular pore size, high specific surface area and large pore volume.	price>
R-M-514	Ac-a-benzyl-muramyl-Ala-D-Glu(Lys(trans-(3-nitrocinnamoyl))-NH₂)-NH₂	MDP-C has been synthesized as a non-specific immunomodulator. MDP-C induces strong cytolytic activity by macrophages on P388 leukemia cells and cytotoxic activity by cytotoxic T lymphcytes (CTLs) on P815 mastocytoma cells.	price>
R-R-1671	Ixabepilone CAS No.219989-84-1	Ixabepilone (BMS-247550)/CAS No.219989-84-1 is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.	price>
R-M-296	DIR iodide(dark red fluorescence)	DiR[1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide] is a lipophilic, near infrared fluorescent cyanine dye. This dye is often used to label other lipid soluble biological structures and cell plasma membrane. The fluorescence intensity of these environmentally sensitive fluorescent dyes is very weak before they enter the cell membrane, and increases greatly when they combine with the cell membrane. It has the characteristics of high extinction coefficient, j-dependence and short lifetime of excited state. DiR [1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide] has strong near-infrared light penetrating cells or tissues and low autofluorescence level in the near-infrared region, which makes it especially suitable for in vivo imaging or tracing experiments.	price>
R-M-515	Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt	Acetyl-calpastatin 27 peptide, AC27P, a calpain inhibitor homologous to the minimal inhibitory domain I of human calpastatin, was shown to modulate the amyloid β-protein 42 secretion ratio. This finding might point to the possibility of exploring compounds that inhibit Aβ42 secretion.	price>
R-R-1672	Tauroursodeoxycholate-d4 sodium CAS No.2410279-95-5	Tauroursodeoxycholate-d4 (sodium)/CAS No.2410279-95-5 is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>
R-M-297	DiD(red fluorescence)	DiD（1,1-Dioctadecyl-3,3,3,3-tetramethylindodicarbocyanine）is a lipophilic fluorescent dye, which can be used to dye cell membrane and other liposoluble biological structures. The fluorescence intensity of these environmentally sensitive fluorescent dyes is very weak before they enter the cell membrane, and increases greatly when they combine with the cell membrane. It has the characteristics of high extinction coefficient, j-dependence and short lifetime of excited state. As a derivative of DiI, DiD（1,1-Dioctadecyl-3,3,3,3-tetramethylindodicarbocyanine）has the excitation and emission spectra of red light migration, which makes it particularly suitable for labeling cells with significant autofluorescence effect.	price>
R-M-A516	Acetylcholine Receptor α₁ (129-145) (human, bovine, rat, mouse)	This fragment of a conserved sequence in nicotinic acetylcholine receptor activates T helper lymphocytes and induces the production of autoantibodies that cause electrophysiologic signs of experimental autoimmune myasthenia gravis. EIIVTHFPFDEQNCSMK may be useful in the development of a peptide-based antigen-specific immunotherapy of myasthenia gravis.	price>

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