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R-M-691 β-Endorphin (30-31) (human) β-Endorphin (30-31) (human),CAS: 7412-78-4 from ruixi.The C-terminal dipeptide Gly-Glu was shown to be an effective neurotrophic factor for the maintenance of acetylcholinesterase at both superior cervical ganglia in the denervated cat. Moreover,β-endorphin can bind to serum glycoproteins at sites for which glycyl-L-glutamic acid competes. A potential impurity of glycyl-L-glutamine used as source for L-glutamine. price>
R-R-1844 PARP14 inhibitor H10 CAS No.2084811-68-5 PARP14 inhibitor H10/CAS No.2084811-68-5, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis. price>
R-M-474 Abz-Asp-Asp-Ile-Val-Pro-Cys-Ser-Met-Ser-3-nitro-Tyr-Thr-NH₂ The internally quenched (FRET) substrate Abz-DDIVPCSMSY(NO₂)T-NH₂allows the direct, specific detection of NS3-4A protease activity . price>
R-M-692 γ-Endorphin γ-Endorphin,CAS :60893-02-9 from ruixi.It can be applied to Opioid Research. price>
R-R-1845 Eftozanermin alfa CAS No.1820660-69-2 Eftozanermin alfa (ABBV-621)/CAS No.1820660-69-2 is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies. price>
R-CG-023 DSPE-Se-Se-PEG-alkyne 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-alkyne,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-alkyne).The product(DSPE-Se-Se-PEG-alkyne)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-475 Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH,CAS:827044-38-2 Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B. price>
R-M-693 Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt,CAS: 117399-94-7 from ruixi.Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis. price>
R-R-1846 Puromycin aminonucleoside CAS No.58-60-6 Puromycin aminonucleoside (NSC 3056)/CAS No.58-60-6 is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. Puromycin aminonucleoside induces apoptosis. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase. Puromycin aminonucleoside induces secretion of cell migrasome. price>
R-CG-024 DSPE-Se-Se-PEG-CHO 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-CHO ,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-CHO).The product(DSPE-Se-Se-PEG-CHO)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-476 Abz-Gly-p-nitro-Phe-Pro-OH trifluoroacetate salt Fluorogenic (FRET) substrate for angiotensin I-converting enzyme (ACE). Enzymatic cleavage of Abz-Gly-Nph-Pro yields Abz-Gly-OH emitting at 420 nm. price>
R-M-694 Endothelin-1 (11-21) trifluoroacetate salt Endothelin-1 (11-21) trifluoroacetate salt,IRL-1038 (CAS :144602-02-8) from ruixi.IRL-1038 inhibits ET-B receptor-mediated contraction of guinea-pig ileal and tracheal smooth muscle without any significant agonist activity,but does not affect the ET-A receptor-mediated contraction of rat aortic smooth muscle. price>
R-R-1847 Hsp90-Cdc37-IN-3 CAS No.2361009-68-7 Hsp90-Cdc37-IN-3 (Compound 9)/CAS No.2361009-68-7 is a novel celastrol−imidazole derivative with anticancer activity. Hsp90-Cdc37-IN-3 inhibits Hsp90−Cdc37 by covalent-binding, and induces apoptosis. price>
R-CG-025 DSPE-Se-Se-PEG-OH 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-hydroxyl,DSPE-Se-Se-PEG-OH from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-OH).The product(DSPE-Se-Se-PEG-OH)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-477 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt Abz-Gly-Pro-D-Leu-D-Ala-NHOH (FN439) is a inhibitor of matrix metalloproteinases. It inhibits interstitial and granulocyte collagenases (IC50 = 1 uM), granulocyte gelatinase (IC50 = 30 uM) and skin fibroblast stromelysin (IC50 = 150 uM) but not thermolysin and serine proteinases. It retains activity after incubation with pronase or human granulocyte elastase. price>
R-M-695 Endothelin-2 (human, canine) acetate salt Endothelin-2 (human,canine) acetate salt,CAS:123562-20-9 from ruixi.It can be applied to cardiovascular system & diseases. price>
R-R-1848 Fenoldopam mesylate CAS No.67227-57-0 Fenoldopam mesylate (SKF-82526)/CAS No.67227-57-0 is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis. price>
R-CG-026 DSPE-Se-Se-PEG-fitc 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-fluorescence,DSPE-Se-Se-PEG-fitc from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-fitc).The product(DSPE-Se-Se-PEG-fitc)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). price>
R-M-478 Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt,a broad-spectrum MMP substrate price>
R-R-1849 PTC-028 CAS No.1782970-28-8 PTC-028/CAS No.1782970-28-8 is an inhibitor of stem cell factor BMI-1 in ovarian cancer that is orally bioavailable. PTC-028 selectively inhibits cancer cells while normal cells remain unaffected. PTC-028 downregulates BMI-1, inducing caspase-mediated apoptosis. price>