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Catalog	name	Description	price
R-CG-037	PLGA-Hydrazone(Hyd)-PEG-Alkyne	Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-Alkyne,PLGA-Hyd-PEG-Alkyne from ruixi.Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG Alkyne was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-708	BQ-788 ammonium salt	BQ-788 ammonium salt,CAS : 173326-37-9 from ruixi.It is a synthetic peptide.	price>
R-R-1861	Taltobulin CAS No.228266-40-8	Taltobulin (HTI-286)/CAS No.228266-40-8, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.	price>
R-CG-038	PLGA-Hydrazone(Hyd)-PEG-oh	Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-hydroxyl,PLGA-Hyd-PEG-oh from ruixi.Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG hydroxyl was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-709	BQ-788	In vitro, BQ-788 potently and competitively inhibited ¹²⁵I-labeled ET-1 binding to ET-B receptors on human Girardi heart cells (IC₅₀= 1.2 nM). However, BQ-788 only poorly inhibited ET-1 binding to ET-A receptors on human neuroblastoma cell line SK-N-MC cells (IC₅₀= 1300 nM). Thus the ET-B receptor antagonist BQ788 may be considered as a powerful tool for investigating the role of ET in physiological and pathological processes.	price>
R-R-1862	Taltobulin hydrochloride	Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin hydrochloride inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.	price>
R-PL1052-X	PAMAM-PLGA-NH2	Poly(amidoamine) -Poly(lactic-co-glycolic acid)-polyethylene glycol-Amine，PAMAM-PLGA-NH2 from ruixi.Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies. PAMAM poly (lactide co glycolide) - amine, the dendrimer block copolymer of this product is a unique product of Ruixi biology. The product quality is high and the price is favorable.	price>
R-M-710	BQ-610	BQ-610 is a very potent ET-A receptor antagonist which is about 30000 times more selective for ET-A receptors than for ET-B receptors. Furthermore, it has been found that BQ-610 strongly antagonizes ET-1 induced concentration in porcine coronary artery with a pA₂ value of 8.2.	price>
R-R-1863	Taltobulin trifluoroacetate CAS No.228266-41-9	Taltobulin trifluoroacetate (HTI-286 trifluoroacetate)/CAS No.228266-41-9, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.	price>
R-R-1864	Pladienolide B CAS No.445493-23-2	Pladienolide B/CAS No.445493-23-2 is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis.	price>
R-CG-039	PLGA-Hydrazone(Hyd)-PEG-CHO	Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-hydroxyl,PLGA-Hyd-PEG-CHO from ruixi.Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG CHO was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-712	Bradykinin (1-5) trifluoroacetate salt	The fragment RPPGF and the two dipeptides Phe-Arg and Ser-Pro are obtained by action of angiotensin-converting enzyme (ACE) on bradykinin. RPPGF inhibits thrombin-induced platelet activation, and in high concentration, the pentapeptide inhibits thrombin-induced coagulant activity.	price>
R-R-1865	Milademetan CAS No.1398568-47-2	Mliademetan (DS-3032)/CAS No.1398568-47-2 is an MDM2 inhibitor that is specific and oral for acute myeloid leukemia (AML) research.	price>
R-PL0996-10k	PLGA-thioketal(TK)-PEG-BIOTIN	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-biotin，PLGA-thioketal(TK)-PEG-BIOTIN from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-biotin this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-713	Bradykinin (1-7) acetate salt	Bradykinin (1-7) acetate salt,CAS :23815-87-4 from ruixi.It is a synthetic peptide.	price>
R-R-1866	Erasin	Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis.	price>
R-CG-040	PLGA-thioketal(TK)-PEG-Azide(N3)	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-Azide(N3) ，PLGA-thioketal(TK)-PEG-Azide(N3) from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-Azide(N3) this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>
R-M-714	Lys-Bradykinin acetate salt	Lys-Bradykinin acetate salt,CAS:342-10-9 from ruixi.Kallidin is the precursor of the vasodilator bradykinin.	price>
R-R-1867	ROC-325 CAS No.1859141-26-6	ROC-325/CAS No.1859141-26-6 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis.	price>
R-CG-041	PLGA-thioketal(TK)-PEG-Alkyne	Poly(L-lactide-co-glycolide)-thioketal(TK)-Polyethylene glycol-Alkyne,PLGA-thioketal(TK)-PEG-Alkyne from ruixi.Thioketal was used as ROS reactive nano drug carrier. Reactive oxygen species (ROS) are the main molecules produced by oxidative stress, which play an important role in many physiological and pathological processes. Plga-thioketal (TK) - peg-Alkyne this product has the characteristics of ROS response. PLGA-PEG can be used to prepare micelles, vesicles and other new targeted products. The active groups at the end of the product can be linked to some modified polypeptides, proteins, sugars, folates or antibodies, etc., so that it has an active targeting effect.	price>

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