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Catalog	name	Description	price
R-R-1922	Pinoresinol CAS No.487-36-5	Pinoresinol/CAS No.487-36-5 is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis.	price>
R-CG-090	PCL-Hydrazone(hyd)-peg-Alkyne	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Alkyne,PCL-Hydrazone(hyd)-peg-Alkyne from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG Alkyne was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-774	Granuliberin-R trifluoroacetate salt	Granuliberin-R is a mast cell degranulating peptide, originally isolated from the skin of the frog Rana rugosa.	price>
R-R-1923	EGFR T790M/L858R-IN-2	EGFRT790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFRT790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFRT790M/L858R-IN-2 induces Apoptosis and cell cycle arrest in the G1 phase. EGFRT790M/L858R-IN-2 shows anti-cancer activity.	price>
R-CG-091	PCL-Hydrazone(hyd)-peg-folate(FA)	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-folate,PCL-Hydrazone(hyd)-peg-folate from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG folate was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-775	GRF (1-29) amide (human) acetate salt	GRF (1-29) amide (sermorelin) is the shortest GRF fragment with full biological activity.	price>
R-R-1924	Peimisine CAS No.19773-24-1	Peimisine (Ebeiensine)/CAS No.19773-24-1 is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research.	price>
R-CG-092	PCL-Hydrazone(hyd)-peg-OH	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-hydroxyl ,PCL-Hydrazone(hyd)-peg-OH from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-hydroxyl was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-776	GRF (1-29) amide (rat)	It is a synthetic peptide, only used for scientific research, not for human body.	price>
R-R-1925	Dalotuzumab CAS No.1005389-60-5	Dalotuzumab (MK-0646)/CAS No.1005389-60-5 is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.	price>
R-CG-093	PCL-Hydrazone(hyd)-peg-CHO	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-CHO,PCL-Hydrazone(hyd)-peg-CHO from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-CHO was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-777	GRF (human) acetate salt	GRF is the hypothalamic peptide hormone that specifically stimulates synthesis and release of the growth hormone by somatotropic cells of the anterior pituitary gland.	price>
R-R-1926	GNE-900 CAS No.1200126-26-6	GNE-900/CAS No.1200126-26-6 is a an ATP-competitive, selective, and orally active ChK1 inhibitor with IC50s of 0.0011, 1.5 µM for ChKl, ChK2, respectively. GNE-900 abrogates the G2-M checkpoint, enhances DNA damage, and induces Apoptosis. gemcitabine (HY-17026) and GNE-900 administration shows anti-tumor activity.	price>
R-CG-094	PCL-Hydrazone(hyd)-peg-FITC	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-fluorescence ,PCL-Hydrazone(hyd)-peg-FITC from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-FITC was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-778	GRF (ovine, caprine) trifluoroacetate salt	GRF (ovine, caprine) trifluoroacetate salt,CAS :94948-82-0 from ruixi.It is a synthetic peptide, only used for scientific research, not for human body.	price>
R-R-1927	Actinonin CAS No.13434-13-4	Actinonin ((-)-Actinonin)/CAS No.13434-13-4 is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.	price>
R-CG-095	PCL-Hydrazone(hyd)-peg-Rhodamine B（RB）	Poly(ε-caprolactone)-Hydrazone(hyd)- Rhodamine B（RB）glycol)-fluorescence ,PCL-Hydrazone(hyd)-peg-Rhodamine B（RB） from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-Rhodamine B（RB） was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-779	GRP (human)	GRP, a bombesin-like peptide, is involved in stress-induced anorexia.	price>
R-R-1928	STAT3-IN-12	STAT3-IN-12 is a potent STAT3 signal inhibitor that can inhibit IL-6 induced JAK/STAT3 signalling pathway activation. STAT3-IN-12 inhibits cancer cell growth, migration, and induce cell apoptosis as well as cycle arrest. STAT3-IN-12 can be used in cancer-related research, such as hepatocellular carcinoma (HCC) and oesophageal carcinoma.	price>
R-CG-096	PCL-thioketal(TK)-PEG-biotin	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-biotin,PCL-thioketal(TK)-PEG-biotin from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, PCL-thioketal(TK)-PEG-biotin has ROS response characteristics, so as to realize the drug delivery system.	price>

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