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R-M-771 Cecropin P1 trifluoroacetate salt Cecropin P1 (SWLSKTAKKLENSAKKRISEGIAIAIQGGPR), a homolog of insect cecropins isolated from pig intestine, was thought to be the first mammalian antimicrobial peptide. Later studies showed that the peptide is produced by the intestinal parasitic nematode Ascaris suum. The 31 amino acid peptide is highly potent against Gram-negative bacteria but has a reduced activity against Gram-positive bacteria. A disruptive effect on bacterial membranes has been proposed as mechanism of antimicrobial activity. price>
R-R-1920 Lometrexol CAS No.106400-81-1 Lometrexol (DDATHF)/CAS No.106400-81-1, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor. price>
R-CG-088 PCL-Hydrazone(hyd)-peg-Thiol(sh) Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Thiol,PCL-Hydrazone(hyd)-peg-sh from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-772 Cecropin B (free acid) trifluoroacetate salt Cecropin B (free acid) trifluoroacetate salt ,CAS:203265-23-0 from ruixi.It can be used Antimicrobial & Antiviral Peptides. price>
R-R-1921 Lometrexol hydrate CAS No.1435784-14-7 Lometrexol (DDATHF) hydrate/CAS No.1435784-14-7, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor. price>
R-CG-089 PCL-Hydrazone(hyd)-peg-Azide(N3) Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Thiol,PCL-Hydrazone(hyd)-peg-sh from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-773 Amyloid β-Protein (1-39) trifluoroacetate salt Amyloid β-Protein (1-39) trifluoroacetate salt,CAS:115427-62-8 from ruixi.It can be used Alzheimer Disease. price>
R-R-1922 Pinoresinol CAS No.487-36-5 Pinoresinol/CAS No.487-36-5 is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis. price>
R-CG-090 PCL-Hydrazone(hyd)-peg-Alkyne Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Alkyne,PCL-Hydrazone(hyd)-peg-Alkyne from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG Alkyne was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-774 Granuliberin-R trifluoroacetate salt Granuliberin-R is a mast cell degranulating peptide, originally isolated from the skin of the frog Rana rugosa. price>
R-R-1923 EGFR T790M/L858R-IN-2 EGFRT790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFRT790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFRT790M/L858R-IN-2 induces Apoptosis and cell cycle arrest in the G1 phase. EGFRT790M/L858R-IN-2 shows anti-cancer activity. price>
R-CG-091 PCL-Hydrazone(hyd)-peg-folate(FA) Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-folate,PCL-Hydrazone(hyd)-peg-folate from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG folate was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-775 GRF (1-29) amide (human) acetate salt GRF (1-29) amide (sermorelin) is the shortest GRF fragment with full biological activity. price>
R-R-1924 Peimisine CAS No.19773-24-1 Peimisine (Ebeiensine)/CAS No.19773-24-1 is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research. price>
R-CG-092 PCL-Hydrazone(hyd)-peg-OH Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-hydroxyl ,PCL-Hydrazone(hyd)-peg-OH from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-hydroxyl was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-776 GRF (1-29) amide (rat) It is a synthetic peptide, only used for scientific research, not for human body. price>
R-R-1925 Dalotuzumab CAS No.1005389-60-5 Dalotuzumab (MK-0646)/CAS No.1005389-60-5 is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo. price>
R-CG-093 PCL-Hydrazone(hyd)-peg-CHO Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-CHO,PCL-Hydrazone(hyd)-peg-CHO from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-CHO was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-777 GRF (human) acetate salt GRF is the hypothalamic peptide hormone that specifically stimulates synthesis and release of the growth hormone by somatotropic cells of the anterior pituitary gland. price>
R-R-1926 GNE-900 CAS No.1200126-26-6 GNE-900/CAS No.1200126-26-6 is a an ATP-competitive, selective, and orally active ChK1 inhibitor with IC50s of 0.0011, 1.5 µM for ChKl, ChK2, respectively. GNE-900 abrogates the G2-M checkpoint, enhances DNA damage, and induces Apoptosis. gemcitabine (HY-17026) and GNE-900 administration shows anti-tumor activity. price>