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R-CG-121 mPEG-thioketal(TK)-Mal methoxy polyethylene glycol-thioketal(TK)-Maleimide,mPEG-thioketal(TK)-Mal,Mal-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-806 CRAMP (mouse) trifluoroacetate salt,CAS : 376364-36-2 CRAMP is a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. Functional studies showed CRAMP to be a potent antibiotic against Gram-negative bacteria by inhibiting growth of a variety of bacterial strains and by permeabilizing the inner membrane of E.coli directly. price>
R-R-1955 Bcl-xL antagonist 2 CAS No.1235032-75-3 Bcl-xL antagonist 2/CAS No.1235032-75-3 is a potent, selective, and orally active antagonist of BCL-XL with an IC50 and Ki of 0.091 μM and 65 nM, respectively. Bcl-xL antagonist 2 promotes the apoptosis of cancer cells. Bcl-xL antagonist 2 has the potential for the research of the chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL). price>
R-CG-122 mPEG-thioketal(TK)-NHS methoxy polyethylene glycol-thioketal(TK)-N-hydroxylsuccinimide,mPEG-thioketal(TK)-NHS,NHS-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-807 CRAMP-18 (mouse) trifluoroacetate salt CRAMP-18 (mouse) corresponds to the functional region of the antibacterial peptide CRAMP. It displayed potent antibacterial activity against several bacteria with no hemolytic activity (minimal inhibitory concentration: 12.5-50 µM). price>
R-R-1956 Loncastuximab tesirine CAS No.1879918-31-6 Loncastuximab tesirine/CAS No.1879918-31-6 is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma. price>
R-CG-123 mPEG-thioketal(TK)-biotin methoxy polyethylene glycol-thioketal(TK)-biotin,mPEG-thioketal(TK)-biotin,biotin-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-818 CRF (bovine) trifluoroacetate salt,CAS : 92307-52-3 CRF (bovine) trifluoroacetate salt,CAS : 92307-52-3 from ruixi.It can be applied to pituitary & hypothalamic hormones. price>
R-R-1957 SB-218078 CAS No.135897-06-2 SB-218078/CAS No.135897-06-2 is a potent, selective, ATP-competitive and cell-permeable checkpoint kinase 1 (Chk1) inhibitor that inhibits Chk1 phosphorylation of cdc25C with an IC50 of 15 nM. SB-218078 is less potently inhibits Cdc2 (IC50 of 250 nM) and PKC (IC50 of 1000 nM). SB-218078 causes apoptosis by DNA damage and cell cycle arrest. price>
R-CG-124 mPEG-thioketal(TK)-sh methoxy polyethylene glycol-thioketal(TK)-thiol,mPEG-thioketal(TK)-sh,Hs-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-808 CRF (human, rat) acetate salt CRF (corticotropin-releasing factor) is a 41-peptide produced mainly in the hypothalamus. The peptide hormone stimulates ACTH release from the anterior lobe of the pituitary gland. CRH plays an important role in the endocrine, behavioral, and immune response to stress and probably as well in the regulation of energy balance. price>
R-R-1958 Periplocin CAS No.13137-64-9 Periplocin/CAS No.13137-64-9 is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase. price>
R-CG-125 mPEG-thioketal(TK)-N3 methoxy polyethylene glycol-thioketal(TK)-Azide,mPEG-thioketal(TK)-N3,Azide-thioketal(TK)-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-809 Biotinyl-CRF (human, rat),CAS : 105883-79-2 Biotinyl-CRF (human, rat),CAS : 105883-79-2 from ruixi. It is a kind of biotinylated peptides, which can be applied to pituitary & hypothalic hormones. price>
R-R-1959 AS-99 TFA AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. price>
R-CG-126 mPEG-thioketal(TK)-Alkyne methoxy polyethylene glycol-thioketal(TK)-Alkyne,mPEG-thioketal(TK)-Alkyne from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-810 Tyr-CRF (human, rat),CAS : 100513-58-4 Tyr-CRF (human, rat),CAS :100513-58-4 from ruixi.It can be applied to pituitary & hypothalamic hormones.It can only be used for scientific research, not for human body. price>
R-R-1960 ADH-6 TFA ADH-6 TFA is a tripyridylamide compound. The self-assembly of the aggregated nucleonic domain of the mutant p53 DBD was abolished by ADH-6. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, thereby restoring p53 transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential to study cancer diseases. price>
R-MP-001 mpeg-pALD(propionaldehyde) mpeg-pALD(propionaldehyde),mPEG-aldehyde,mPEG-ALD,Methoxy-PEG-Propionaldehyde,mPEG-Propionaldehyde,Methoxypoly(ethylene glycol)-propionaldehyde from ruixi.mPEG-aldehyde (propionaldehyde) reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. price>
R-M-811 CCAP Native and synthetic CCAP displayed high ino- and chronotropic effects on a semi-isolated crab heart preparation. price>