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Catalog	name	Description	price
R-CG-134	Glycyrrhetinic acid(GA)-peg-Alkyne	Glycyrrhetinic acid(GA)-peg-Alkyne,Glycyrrhetinic acid-polyethylene glycol-Alkyne ,GA-PEG-Alkyne from ruixi.The main functional components of Glycyrrhiza are glycyrrhizic acid. The molecular structure of glycyrrhizic acid contains 1 molecule glycyrrhetinic acid and 2 molecule glucuronic acid. Glycyrrhetinic acid has anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, anti-virus and other functions.	price>
R-M-819	DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt	The fluorogenic HIV-1 protease substrate DABCYL-Gaba-SQNYPIVQ-EDANS consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.	price>
R-R-1969	ACA-28 CAS No.948044-25-5	ACA-28 (compound 2a)/CAS No.948044-25-5 is a potent ERK MAPK signaling modulator. ACA-28 selectively inhibits cancer cell growth by inducing apoptosis with ERK hyperactivation ACA-28 inhibits cell growth of melanoma cells (SK-MEL-28) and normal melanocytes (NHEM), with IC50 values of 5.3 and 10.1 μM, respectively.	price>
R-HF-016	Hyaluronate（HA）-SS-Diacerein,MW:100K	Hyaluronate（HA）-SS-Diacerein MW:100K,Hyaluronate-S-S-Diacerein,MW:100K , Hyaluronate(HA)100k-SS-1,8-Diacetoxy-3-carboxyanthraquinone ，Hyaluronate（(HA)100k-SS-Diacerein from ruixi.Disulfide bond has the Glutathione (GSH) reduction response.Ruixi biotech provides high-quality products, which are customized by Ruixi.	price>
R-M-820	Defensin 5 (human) trifluoroacetate salt	Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine.As a biomarker, HD 5 might be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn colitis (high levels of HD 5).	price>
R-R-1970	DIM-C-pPhOH CAS No.151358-47-3	DIM-C-pPhOH/CAS No.151358-47-3 is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhOH inhibits cancer cell growth and mTOR signaling, induce apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.	price>
R-CG-135	Hyaluronate(HA)-Hyd-DOX	Hyaluronate-Hydrazone-Doxorubicin,Hyaluronate(HA)-Hyd-DOX,HA-Hyd-DOX from ruixi.Hydrazone bond has pH response effect. Ha-hyd-dox is used for the acid triggered release of adriamycin via hydrazone bond. The product is a amphiphilic polymer precursor drug, and the prepared nanoparticles have a spherical core-shell structure. Ha hyd DOX nanoparticles have good stability in vitro. The drug release curve shows that DOX release is obviously regulated by pH gradient.	price>
R-M-821	Defensin HNP-1 (human) trifluoroacetate salt,CAS : 148093-65-6	Defensin HNP-1 (human) trifluoroacetate salt,CAS : 148093-65-6 from ruixi. It is a kind of Antimicrobial peptide. It can be applied to Antimicrobial & Antiviral Peptides.	price>
R-R-1971	3,6-Dihydroxyflavone CAS No.108238-41-1	3,6-Dihydroxyflavone/CAS No.108238-41-1 is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation.	price>
R-CG-136	Hyaluronate(HA)-Hyd-Paclitaxel（PTX）	Hyaluronate-Hydrazone-Doxorubicin,Hyaluronate(HA)-Hyd-DOX,HA-Hyd-DOX from ruixi.Hydrazone bond has pH response effect. Ha-hyd-dox is used for the acid triggered release of adriamycin via hydrazone bond. The product is a amphiphilic polymer precursor drug, and the prepared nanoparticles have a spherical core-shell structure. Ha hyd DOX nanoparticles have good stability in vitro. The drug release curve shows that DOX release is obviously regulated by pH gradient.	price>
R-M-822	Defensin HNP-2 (human) trifluoroacetate salt	Defensin HNP-2 (human) trifluoroacetate salt,CAS :120721-97-3 from ruixi.It is a kind of Antimicrobial peptide , it can be applied to antimicrobial & antiviral peptides.	price>
R-R-1972	GK563 CAS No.2351820-19-2	GK563/CAS No.2351820-19-2 is a selective Ca2+-independent phospholipase A2 (GVIA iPLA2) inhibitor with an IC50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA2 than GIVA cPLA2. GK563 reduces β-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.	price>
R-CG-137	mPEG-PGA-g-PEI-g-DXMS（20%）	mPEG-PGA-g-PEI-g-DXMS，Methoxy-poly(ethylene glycol)-poly(L-glutamic acid)-graft-Polyethylenimine-graft-Dexamethasone from ruixi.MPEG copolymerized PGA, and then grafted to Pei. Thus, mpeg-pga-g-pei is formed. Then dexamethasone was grafted onto mpeg-pga-g-pei. Finally, the product was prepared into nanoparticles with positive charge for drug delivery system.	price>
R-M-823	Endotrophin (mouse) trifluoroacetate salt,CAS:1678414-54-4	Endotrophin is a carboxyl-terminal cleavage product of collagen 6 alpha-3 chain which is produced and released by adipocytes and massively upregulated in malignant tumors of breast, liver colon and pancreas. Endotrophin provides a link between obesity and aggressive tumor growth and may serve as sensitive diagnostic marker and valid therapeutic target for designing better strategies to treat cancer and ameliorate obesity-induced insulin resistance.	price>
R-R-1973	Lobetyolin CAS No.129277-38-9	Lobetyolin/CAS No.129277-38-9, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism. Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-DZPE-001	mPEG-PGA-g-PEI	Methoxy-poly(ethylene glycol)-poly(L-glutamic acid)-graft-Polyethylenimine，mPEG-PGA-g-PEI from ruixi.Mpeg-pga-g-pei was obtained by copolymerizing PGA with MPEG and grafting it to Pei.Finally, the product has a drug delivery system.	price>
R-M-824	Endothelin (16-21) trifluoroacetate salt,CAS : 121377-67-1	The endothelin C-terminal fragment HLDIIW was found to be a full agonist at ET-B receptors while being inactive or weakly active at ET-A receptors. The tryptophan in position 21 played a key role in the activity of ET (16-21) at the ET-B receptors.	price>
R-R-1974	9-ING-41 CAS No.1034895-42-5	9-ING-41 (Elraglusib)/CAS No.1034895-42-5 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents.	price>
R-PLF32150	mPEG2000-PLA1300-FITC	Methoxy-poly(ethylene glycol)2k-Poly(D,L-lactide) 1300-FITC,mPEG2000-PLA1300-FITC ,mPEG-PLA-Fluorescein from ruixi.MPEG copolymerized PLA,then fluorescein modified MPEG PLA.Thus forming the final product mPEG2000-PLA1300-FITC.The product can be used in drug delivery system.	price>
R-M-825	Endotoxin Inhibitor	The cyclic peptide KTKCKFLKKC has ben shown to form a strong complex with lipid A, the toxic component of the endotoxin lipopolysaccharide (LPS) . It detoxifies LPS in vitro and prevents LPS-induced cytokine release and lethality in vivo. Furthermore, it shows neither antibiotic activity nor toxicity . KTKCKFLKKC bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy.	price>

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