Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-DZ001-SH	Loratadine-SH	Loratadine-thiol,Loratadine-SH from ruixi..Ruixi is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click chemistry and macrocyclic ligands.	price>
R-C-322	TPE-Acrylic acid	TPE acrylic acid,acrylic acid modified tetrastyryl aggregation induced luminescence material,ex(nm):300-400,EM (nm):450.	price>
R-R-2022	Carubicin hydrochloride CAS No.52794-97-5	Carubicin hydrochloride/CAS No.52794-97-5 is a microbially-derived compound. Carubicin hydrochloride is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin hydrochloride also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin hydrochloride has the potential for the research of cancer diseases.	price>
R-DZ001-NH2	Loratadine-NH2	Loratadine-NH2，Loratadine-Amine，Loratadine-Amino from ruixi.Ruixi is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click chemistry and macrocyclic ligands.	price>
R-R-2023	NU9056 CAS No.1450644-28-6	NU9056/CAS No.1450644-28-6 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an of 2 µM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells.	price>
R-DZ010	DOTA-Tetrazine	DOTA-Tetrazine,DOTA-TZ from ruixi.Dota is a twelve membered tetraazamacrocyclic ligand.Tetrazine is a six membered heterocyclic compound containing four nitrogen atoms.Tetrazine has been used for many years in the fields of total synthesis of natural products, preparation of energetic compounds and metal coordination chemistry. Dota tetrazine can be used as a molecular imaging probe or as a delivery carrier for targeted drugs.	price>
R-C-324	TPE-(COOH)4 Na	The tetrastyrene tetracarboxyl group of sodium salt is a water-soluble AIE material with molecular weight of 660.02.	price>
R-R-2024	MI-192 CAS No.1415340-63-4	MI-192/CAS No.1415340-63-4 is a selective HDAC2 and HDAC3 inhibitor with IC50s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. Anticaner and neuroprotective activities.	price>
R-OA-001	CY3-Oleic acid	Cyanine3-Oleic acid,CY3-Oleic acid,Oleic acid-CY3 from ruixi. CY3 labeled Heparin.Ruixibio provides a variety of chemically functionalized and bioconjugated Oleic acid with different functionality. These functional Oleic acid products were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.	price>
R-C-325	TPE-COOH	Aggregation induced emission (AIE) is a phenomenon discovered by academician Tang benzhong team in 2001.It is a kind of non luminescent thiazole derivative in the form of single molecule in solution.With the gradual evaporation of solvent,the fluorescence gradually increases.Tetrastyrene is a kind of important aggregation fluorescent dyes.When tetraphenylene is in the aggregated state or in the solid state,the intramolecular rotation is limited and the non radiative channel is blocked,and the excited molecules return to the ground state by emitting photons. Tetraphenylene(TPE)is an outstanding member of AIE system because of its easy modification and high luminous efficiency.Design and prepare two kinds of four-phase silicon-based materials.	price>
R-R-2025	7,8-Dihydroneopterin CAS No.1218-98-0	7,8-Dihydroneopterin/CAS No.1218-98-0, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases.	price>
R-OA-002	CY7-Oleic acid	Cyanine7-Oleic acid,CY7-Oleic acid,Oleic acid-CY7 from ruixi. CY7 labeled Heparin.Ruixibio provides a variety of chemically functionalized and bioconjugated Oleic acid with different functionality. These functional Oleic acid products were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.	price>
R-C-326	TPE-(OH)4	Aggregation induced luminescence (AIE) is a new type of organic light-emitting material with opposite photophysical properties to the traditional aggregated fluorescence quenching dye molecules.It can be widely used in many fields,such as chemical biological sensing,biological probe and imaging,integration of diagnosis and treatment,optoelectronic devices and so on.Tetrastyrene (TPE) has excellent AIE properties and can be easily synthesized by McMurray coupling reaction.	price>
R-R-2026	K-7174 dihydrochloride CAS No.191089-60-8	K-7174 dihydrochloride/CAS No.191089-60-8 is an orally active proteasome and GATA inhibitor. K-7174 dihydrochloride is a cell adhesion inhibitor. K-7174 dihydrochloride induces cell apoptosis. K-7174 dihydrochloride shows antitumor activities, it can be used for the research of cancer.	price>
R-ZTPM-301	Paclitaxel-TK-PEG-3-Methyladenine（MA）	Paclitaxel-TK-PEG-3-Methyladenine（MA），Paclitaxel-thioketal- polyethylene glycol-3-Methyladenine，Paclitaxel-TK-PEG-3-MA from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, Paclitaxel-TK-PEG-3-Methyladenine（MA） has ROS response characteristics, so as to realize the drug delivery system.	price>
R-C-327	TPE-NCS	Aggregation induced emission (AIE) is a kind of phenomenon that molecules in solution which do not emit light or have weak luminescence enhance their luminescence after aggregation.Single TPE molecules are arranged orderly in TPE NCS,which limits the intramolecular free rotation of benzene ring,reduces the non radiative relaxation and further enhances ECL.Compared with the blue fluorescence emitted by the band gap transition of TPE NCS,the ECL spectrum of TPE NCS is red shifted to the near infrared region (678 nm),Compared with the traditional near-infrared ECL luminescent materials,tetrastyrene nanocrystals (TPE NCS) improve the electron hole recombination efficiency by aggregating TPE molecules,inhibit the non radiative transition,and realize the aggregation induced enhanced ECL emission.	price>
R-R-2027	Famitinib CAS No.1044040-56-3	Famitinib (SHR1020)/CAS No.1044040-56-3, an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit, VEGFR-2 and PDGFRβ with IC50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis.	price>
R-DZ021	PLA-PCL-PEG-WKVRKSFFKLQGK（Biotin）	PLA-PCL-PEG-WKVRKSFFKLQGK（Biotin），Poly(D,L-lactide)-polyethylene glycol-WKVRKSFFKLQGK（Biotin）from ruixi.Ruixi is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click chemistry and macrocyclic ligands.	price>
R-C-328	TPE-TPP	Based on the aggregation induced luminescence material tpe-tpp,the characteristics of photon fluorescence were studied.Using tpe-tpp as a fluorescence probe,the advantages and disadvantages of three photon and two-photon fluorescence imaging technology under 1020nm and 810nm femtosecond laser excitation were compared.Several advantages of three photon fluorescence imaging technology based on tpe-tpp were proposed,including high photobleaching resistance,low light damage, high spatial resolution and high signal to background ratio.Three photon fluorescence imaging of tpe-tpp was also used to observe the change trend of mitochondrial membrane potential in real time and with high sensitivity.In addition,tpe-tpp can be used to label neurons and microglia in mouse brain.Through microinjection,the real-time and long-time two-photon fluorescence imaging of microglia in mouse brain excited by 740nm femtosecond laser was realized.Three photon fluorescence imaging of brain tissue sections is performed to obtain high-quality imaging, which has great significance and application prospects for the study of deep nervous system activity in vivo.	price>
R-R-2028	JNJ-1013 CAS No.2597343-08-1	JNJ-1013/CAS No.2597343-08-1 is a potent and selective IRAK1 degrader with an IC50s of 72, 443, 1071 nM for IRAK1, IRAK4, VHL FP respectively. JNJ-1013 induces Apoptosis and increases the expression of cleavaged PARP. JNJ-1013 decreases the expression IRAK1, p-IKBα, pSTAT3(Tyr705).	price>

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