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Catalog	name	Description	price
R-R-2340	SJ1008030 formic	SJ1008030 (compound 8) formic is a JAK2 PROTAC which selectively degrades JAK2. SJ1008030 formic inhibits MHH–CALL-4 cell growth with an IC50 of 5.4 nM. SJ1008030 formic can be used for the research of leukemia.	price>
R-C-641	PD169316 cas:152121-53-4	PD 169316 is a potent,cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM.PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71.PD169316 shows antiviral activity against Enterovirus71.	price>
R-R-2341	Itacnosertib (hydrocholide) CAS No.2409543-84-4	Itacnosertib hydrocholide/CAS No.2409543-84-4 is an inhibitor of JAK2, ACVR1 (ALK2) and ALK5.	price>
R-C-642	PD153035HCl CAS No. 183322-45-4	PD153035 HCl(SU-5271 HCl,AG1517 HCl,ZM 252868 HCl) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR,FGFR,CSF-1,InsR and Src.	price>
R-R-2342	(R,R)-VVD-118313 CAS No.2875046-31-2	(R,R)-VVD-118313/CAS No.2875046-31-2 is the isomer of VVD-118313 (HY-151385). VVD-118313 is a selective JAK1 inhibitor and blocks JAK1-dependent trans-phosphorylation and cytokine signaling. VVD-118313 can be used for research of cancer. (R,R)-VVD-118313 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-643	BIX02188 CAS:1094614-84-2	BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM.BIX02188 inhibits ERK5 catalytic activity,with an IC50 of 810 nM.	price>
R-R-2343	GDC-4379 CAS No.2252277-73-7	GDC-4379/CAS No.2252277-73-7 is a JAK1 inhibitor that can be used for the research of asthma.	price>
R-C-644	BIX02189 CAS:1094614-85-3	BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM,also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays,and does not inhibit closely related kinases MEK1,MEK2,ERK2,and JNK2.	price>
R-R-2344	Tubulin/JAK2-IN-1 CAS No.2933938-46-4	Tubulin/JAK2-IN-1 (compound 7g)/CAS No.2933938-46-4 is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. Tubulin/JAK2-IN-1 has potent antiproliferative activity against the cancer cells.	price>
R-C-645	CP945598（Otenabant ） cas:686344-29-6	Otenabant is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM,exhibits 10,000-fold greater selectivity against human CB2 receptor.	price>
R-R-2345	Tyk2-IN-8 CAS No.2704587-24-4	Tyk2-IN-8/CAS No.2704587-24-4 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease.	price>
R-C-646	GW9508 cas:885101-89-3	GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor(GPCR)GRP40/FFA1 receptor (EC50 ?50 nM)with reduced activity towards family members GRP120 (EC50?3.5 μM), GRP41/GRP43 (EC50>50 μM),as well as a panel of eight other free fatty acid (FFA) and prostaglandin receptors.	price>
R-R-2346	Filgotinib-d4 CAS No.2041095-50-3	Filgotinib-d4/CAS No.2041095-50-3 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.	price>
R-C-647	CI994 cas:112522-64-2	Tacedinaline(N-acetyldinaline)is an inhibitor of the histone deacetylase(HDAC) with IC50s of 0.9,0.9,1.2μM for recombinant HDAC 1,2 and 3 respectively.	price>
R-R-2347	LFM-A13 CAS No.62004-35-7	LFM-A13/CAS No.62004-35-7 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research.	price>
R-C-648	AT7519HCL cas:902135-91-5	AT7519 Hydrochloride is a potent inhibitor of CDKs,with IC50s of 210,47,100,13, 170,and <10 nM for CDK1,CDK2,CDK4 to CDK6,and CDK9,respectively.	price>
R-R-2348	(3R,4S)-Tofacitinib CAS No.1092578-46-5	(3R,4S)-Tofacitinib/CAS No.1092578-46-5 is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.	price>
R-C-649	StemRegenin 1 (SR1) CAS No. 1227633-49-9	StemRegenin 1(SR1)is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).	price>
R-R-2349	Fosifidancitinib CAS No.1237168-58-9	Fosifidancitinib/CAS No.1237168-58-9 is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases.	price>
R-C-650	KI8751 cas:228559-41-9	Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays.	price>

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