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Catalog	name	Description	price
R-R-2396	HODHBt CAS No.28230-32-2	HODHBt (HOOBt)/CAS No.28230-32-2 inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer.	price>
R-C-697	Amine Functional Mesoporous silica coating NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Amino mesoporous silica coated core-shell upconversion nanoparticles (980 excitation, green light) have an emission wavelength of 540/650 nm±2 nm,a surface ligand of NH2,and a particle size of 50±10nm under electron microscope. The solvent is water.	price>
R-R-2397	Peramivir CAS No.330600-85-6	Peramivir/CAS No.330600-85-6 is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19.	price>
R-C-698	Amine Functional Mesoporous silica coating NaYF4:Yb,Tm@NaYF4(980 excited, blue light)	The up conversion nanoparticles (980 excited,blue light) with aminated mesoporous silica core-shell structure emit at 365/450/470 nm ±15 nm,the surface ligand is NH2,and the particle size under electron microscope is 50±15.The solvent is water.	price>
R-R-2398	Tetramethylcurcumin CAS No.52328-97-9	Tetramethylcurcumin (FLLL31)/CAS No.52328-97-9, derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects.	price>
R-C-699	Amine Functional Mesoporous silica coating NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excitation, green light)	Amino mesoporous silica coated core-shell upconversion nanoparticles (808 excitation, green light) have an emission wavelength of 540/650 nm±15 nm,a surface ligand of NH2,and a particle size of 50 ± 15 under electron microscope. The solvent is water.	price>
R-R-2399	(R)-Lisofylline CAS No.100324-81-0	(R)-Lisofylline ((R)-Lisophylline)/CAS No.100324-81-0 is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research.	price>
R-C-700	Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light)	Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),The emission wavelength is 365/450/470nm15 nm,the surface ligand is NH2,the particle size under electron microscope is 50±15,and the solvent is water.	price>
R-R-2400	STAT3-IN-15	STAT3-IN-15 is a potent and orally active STAT3 inhibitor against idiopathic pulmonary fibrosis (IPF). STAT3-IN-15 inhibits STAT3 phosphorylation. STAT3-IN-15 also inhibits the migration and deformation of epithelial cells induced by TGF-β1 and inhibit epithelial-mesenchymal transition (EMT).	price>
R-C-701	Streptavidin modified NaYF4:Yb,Er(980 excitation, green light)	Streptavidin modified upconversion nanoparticles (980 excitation, green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2401	W1131 CAS No.2740522-79-4	W1131/CAS No.2740522-79-4 is a potent STAT3 inhibitor, triggering ferroptosis. W1131 suppresses cancer progression in gastric cancer cell subcutaneous xenograft model, organoids model, and PDX model. W1131 effectively alleviates chemical resistance of cancer cells to 5-FU (HY-90006). W1131 regulates cell cycle, DNA damage response, and oxidative phosphorylation, including IL6-JAK-STAT3 pathway and ferroptosis pathway.	price>
R-C-702	Streptavidin modified NaYF4:Yb,Tm (980 excitation, blue light)	Streptavidin modified upconversion nanoparticles(980 excitation,blue light), The emission wavelength is 365/450/470nm±15 nm,the surface ligand is streptavidin,and the particle size is 20-30nm under electron microscope.The solvent is water.	price>
R-R-2402	ENMD-1198 CAS No.864668-87-1	ENMD-1198 (IRC-110160)/CAS No.864668-87-1, an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization.	price>
R-C-703	Streptavidin modified NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2403	C188 CAS No.823828-18-8	C188/CAS No.823828-18-8 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM).	price>
R-C-704	Streptavidin modified NaYF4:Yb,Tm@NaYF4(980 excitation, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm ±15 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>
R-R-2404	CMD178 TFA	CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.	price>
R-C-705	Streptavidin modified NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light),core-shell	Streptavidin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2405	Stafib-2 CAS No.2097938-74-2	Stafib-2/CAS No.2097938-74-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability.	price>
R-C-706	Streptavidin modified NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(808 excited,blue light). The emission wavelength is 365/450/470 nm±2 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>

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